标题
A Huntingtin Peptide Inhibits PolyQ-Huntingtin Associated Defects
作者
关键词
-
出版物
PLoS One
Volume 8, Issue 7, Pages e68775
出版商
Public Library of Science (PLoS)
发表日期
2013-07-05
DOI
10.1371/journal.pone.0068775
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Neuronal aggregates are associated with phenotypic onset in the R6/2 Huntington's disease transgenic mouse
- (2012) Randi-Michelle Cowin et al. BEHAVIOURAL BRAIN RESEARCH
- Huntingtin Aggregation Kinetics and Their Pathological Role in a Drosophila Huntington’s Disease Model
- (2011) Kurt R. Weiss et al. GENETICS
- Important neuronal toxicity of microtubule-bound Tau in vivo in Drosophila
- (2011) Yasmina Talmat-Amar et al. HUMAN MOLECULAR GENETICS
- Secondary Structures of Native and Pathogenic Huntingtin N-Terminal Fragments
- (2011) Maciej Długosz et al. JOURNAL OF PHYSICAL CHEMISTRY B
- Small Changes, Big Impact
- (2011) Dagmar E. Ehrnhoefer et al. NEUROSCIENTIST
- Perturbation with Intrabodies Reveals That Calpain Cleavage Is Required for Degradation of Huntingtin Exon 1
- (2011) Amber L. Southwell et al. PLoS One
- Engineered antibody therapies to counteract mutant huntingtin and related toxic intracellular proteins
- (2011) David C. Butler et al. PROGRESS IN NEUROBIOLOGY
- Early or Late-Stage Anti-N-Terminal Huntingtin Intrabody Gene Therapy Reduces Pathological Features in B6.HDR6/1 Mice
- (2010) Abigail Snyder-Keller et al. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
- Harnessing chaperone-mediated autophagy for the selective degradation of mutant huntingtin protein
- (2010) Peter O Bauer et al. NATURE BIOTECHNOLOGY
- Matrix Metalloproteinases Are Modifiers of Huntingtin Proteolysis and Toxicity in Huntington's Disease
- (2010) John P. Miller et al. NEURON
- Molecular Mechanisms and Potential Therapeutical Targets in Huntington's Disease
- (2010) Chiara Zuccato et al. PHYSIOLOGICAL REVIEWS
- Small molecule drug discovery for Huntington's Disease
- (2009) Wolfgang Fecke et al. DRUG DISCOVERY TODAY
- Genomic mapping and expression patterns of C380, OK6 and D42 enhancer trap lines in the larval nervous system of Drosophila
- (2009) Subhabrata Sanyal GENE EXPRESSION PATTERNS
- Intrabody Gene Therapy Ameliorates Motor, Cognitive, and Neuropathological Symptoms in Multiple Mouse Models of Huntington's Disease
- (2009) A. L. Southwell et al. JOURNAL OF NEUROSCIENCE
- Pathogenic huntingtin inhibits fast axonal transport by activating JNK3 and phosphorylating kinesin
- (2009) Gerardo A Morfini et al. NATURE NEUROSCIENCE
- The chaperonin TRiC blocks a huntingtin sequence element that promotes the conformational switch to aggregation
- (2009) Stephen Tam et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Polyglutamine disruption of the huntingtin exon 1 N terminus triggers a complex aggregation mechanism
- (2009) Ashwani K Thakur et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Live axonal transport disruption by mutant huntingtin fragments in Drosophila motor neuron axons
- (2009) C. Sinadinos et al. NEUROBIOLOGY OF DISEASE
- Combinational approach of intrabody with enhanced Hsp70 expression addresses multiple pathologies in a fly model of Huntington’s disease
- (2008) J. A. McLear et al. FASEB JOURNAL
- Phosphorylation of mutant huntingtin at S421 restores anterograde and retrograde transport in neurons
- (2008) Diana Zala et al. HUMAN MOLECULAR GENETICS
- Protective role of Engrailed in a Drosophila model of Huntington's disease
- (2008) Bruno Mugat et al. HUMAN MOLECULAR GENETICS
- Intrabodies Binding the Proline-Rich Domains of Mutant Huntingtin Increase Its Turnover and Reduce Neurotoxicity
- (2008) A. L. Southwell et al. JOURNAL OF NEUROSCIENCE
- Phosphorylation of huntingtin reduces the accumulation of its nuclear fragments
- (2008) Simon C. Warby et al. MOLECULAR AND CELLULAR NEUROSCIENCE
- Suppression of Neurodegeneration and Increased Neurotransmission Caused by Expanded Full-Length Huntingtin Accumulating in the Cytoplasm
- (2008) Eliana Romero et al. NEURON
Create your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create NowBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started