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Immunology
Shunichi Oka, Xiaoyan Li, Fuyuki Sato, Fengzhu Zhang, Nitesh Tewari, Chongchong Chen, Liangjun Zhong, Makoto Makishima, Yi Liu, Ujjal K. Bhawal
Summary: This study investigated the impact of Dec2 deficiency on autophagy in PDLFs using experimental models and in vitro methods. Results showed that Dec2 deficiency can regulate autophagy to alleviate LPS-induced inflammation in PDLFs.
IMMUNITY INFLAMMATION AND DISEASE
(2021)
Review
Immunology
Noor Bala, Alexander I. McGurk, Tiago Zilch, Anastasia N. Rup, Evan M. Carter, Scott A. Leddon, Deborah J. Fowell
Summary: Successful immunity relies on the coordinated recruitment of diverse immune cell subsets to target tissues, with effector T cells navigating through tissues based on chemotactic and structural cues. Spatial preference in T cell activation has been uncovered by tissue-wide visualization, with activation niches regulated by site-specific chemokines for optimized effector function.
IMMUNOLOGICAL REVIEWS
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Medicine, Research & Experimental
Spiros Georgakis, Katerina Gkirtzimanaki, Garyfalia Papadaki, Hariklia Gakiopoulou, Elias Drakos, Maija-Leena Eloranta, Manousos Makridakis, Georgia Kontostathi, Jerome Zoidakis, Eirini Baira, Lars Ronnblom, Dimitrios T. Boumpas, Prodromos Sidiropoulos, Panayotis Verginis, George Bertsias
Summary: IL-33, released during cell death, interacts with NETs in SLE patients, stimulating IFN-alpha production, and linking neutrophil activation, type I IFN production, and end-organ inflammation.
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Pharmacology & Pharmacy
Qiuhua Cao, Yanting Lin, Chongxiu Yue, Yue Wang, Fei Quan, Xinmeng Cui, Ran Bi, Xinying Tang, Yong Yang, Chen Wang, Xianjing Li, Xinghua Gao
Summary: Deficiency of IL-6 can promote the development of ulcerative colitis and cause adverse immune reactions, mainly by regulating chemokines, cell migration, and inflammatory responses to affect disease progression.
EUROPEAN JOURNAL OF PHARMACOLOGY
(2021)
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Surgery
Ravi Dhital, Shashi Anand, Brianna Graber, Qiang Zeng, Victoria M. Velazquez, Srinivasa R. Boddeda, James R. Fitch, Ranjana W. Minz, Mukut Minz, Ashish Sharma, Rachel Cianciolo, Masako Shimamura
Summary: Human cytomegalovirus (HCMV) infection is associated with renal allograft failure. CMV promotes allograft damage via cytokine-mediated Th1/17 cell recruitment. Pharmacologic inhibition of the Th17 cell signature cytokine, IL-17A, ameliorates CMV-associated allograft damage.
AMERICAN JOURNAL OF TRANSPLANTATION
(2022)
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Cell Biology
Shachi Pranjal Vyas, Rajeshwar Nath Srivastava, Ritobrata Goswami
Summary: This study investigated the TLR2 signaling pathway in Th9 cells and its regulation by calcitriol. The findings suggest that TLR2 signals via IL-33/ST2 in Th9 cells, and calcitriol can attenuate TLR2 signaling. Low serum vitamin D3 levels are associated with increased IL-9 and TLR2 expression as well as disease severity in rheumatoid arthritis patients.
MOLECULAR AND CELLULAR BIOCHEMISTRY
(2021)
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Hematology
Vanessa Morales-Tirado, Dorothy K. Sojka, Shoshana D. Katzman, Christopher A. Lazarski, Fred D. Finkelman, Joseph F. Urban, Deborah J. Fowell
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Biochemistry & Molecular Biology
Shoshana D. Katzman, Katrina K. Hoyer, Hans Dooms, Iris K. Gratz, Michael D. Rosenblum, Jonathan S. Paw, Sara H. Isakson, Abul K. Abbas
Article
Immunology
Eugenio Gallo, Shoshana Katzman, Alejandro V. Villarino
EUROPEAN JOURNAL OF IMMUNOLOGY
(2012)
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Immunology
Alejandro V. Villarino, Shoshana D. Katzman, Eugenio Gallo, Omer Miller, Shuwei Jiang, Michael T. McManus, Abul K. Abbas
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Medicine, Research & Experimental
Shoshana D. Katzman, Deborah J. Fowell
JOURNAL OF CLINICAL INVESTIGATION
(2008)
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Immunology
Justin J. Taylor, Ryan J. Martinez, Philip J. Titcombe, Laura O. Barsness, Stephanie R. Thomas, Na Zhang, Shoshana D. Katzman, Marc K. Jenkins, Daniel L. Mueller
JOURNAL OF EXPERIMENTAL MEDICINE
(2012)
Article
Immunology
Shoshana D. Katzman, Eugenio Gallo, Katrina K. Hoyer, Abul K. Abbas
JOURNAL OF IMMUNOLOGY
(2011)
Article
Immunology
Sara H. Isakson, Shoshana D. Katzman, Katrina K. Hoyer
JOURNAL OF IMMUNOLOGY
(2012)
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Multidisciplinary Sciences
Shoshana D. Katzman, William E. O'Gorman, Alejandro V. Villarino, Eugenio Gallo, Rachel S. Friedman, Matthew F. Krummel, Garry P. Nolan, Abul K. Abbas
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2010)
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Education, Scientific Disciplines
Shoshana D. Katzman, Jennifer Hurst-Kennedy, Alessandra Barrera, Jennell Talley, Elisabeth Javazon, Mary Diaz, Mary E. Anzovino
Summary: Specifications (specs) grading is a grading system based on mastery of specific educational outcomes, which has been shown to benefit student learning and motivation. In a Cell Biology course, the implementation of specs grading led to improved performance and more-positive attitudes among students.
JOURNAL OF MICROBIOLOGY & BIOLOGY EDUCATION
(2021)
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Education, Scientific Disciplines
Jennifer Hurst-Kennedy, Michael Saum, Cindy Achat-Mendes, Allison D'Costa, Elisabeth Javazon, Shoshana Katzman, Ernest Ricks, Alessandra Barrera
JOURNAL OF MICROBIOLOGY & BIOLOGY EDUCATION
(2020)
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Immunology
Xinyan Zhao, Bo Zheng, Yanfang Huang, Dan Yang, Shoshana Katzman, Chawnshang Chang, Deborah Fowell, Wei-ping Zeng
JOURNAL OF IMMUNOLOGY
(2007)
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Immunology
Byron B. Au-Yeung, Shoshana D. Katzman, Deborah J. Fowell
JOURNAL OF IMMUNOLOGY
(2006)