Global Substrate Profiling of Proteases in Human Neutrophil Extracellular Traps Reveals Consensus Motif Predominantly Contributed by Elastase

Pyocyanin-Enhanced Neutrophil Extracellular Trap Formation Requires the NADPH Oxidase

(2013) Balázs Rada et al.   PLoS One

NETs Are a Source of Citrullinated Autoantigens and Stimulate Inflammatory Responses in Rheumatoid Arthritis

(2013) R. Khandpur et al.   Science Translational Medicine

An Improved Strategy to Recover Large Fragments of Functional Human Neutrophil Extracellular Traps

(2013) Lorena Barrientos et al.   Frontiers in Immunology

Influence of DNA on the Activities and Inhibition of Neutrophil Serine Proteases in Cystic Fibrosis Sputum

(2012) Alice V. Dubois et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

The pig as a model for investigating the role of neutrophil serine proteases in human inflammatory lung diseases

(2012) Déborah Bréa et al.   BIOCHEMICAL JOURNAL

Neutrophil Extracellular Traps Mediate a Host Defense Response to Human Immunodeficiency Virus-1

(2012) Tatsuya Saitoh et al.   Cell Host & Microbe

Infection-induced NETosis is a dynamic process involving neutrophil multitasking in vivo

(2012) Bryan G Yipp et al.   NATURE MEDICINE

Global identification of peptidase specificity by multiplex substrate profiling

(2012) Anthony J O'Donoghue et al.   NATURE METHODS

NSP4, an elastase-related protease in human neutrophils with arginine specificity

(2012) N. C. Perera et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Protease-Activated Drug Development

(2012) Ki Young Choi et al.   Theranostics

PAD4 mediated histone hypercitrullination induces heterochromatin decondensation and chromatin unfolding to form neutrophil extracellular trap-like structures

(2012) Marc Leshner et al.   Frontiers in Immunology

Dying for a cause: NETosis, mechanisms behind an antimicrobial cell death modality

(2011) Q Remijsen et al.   CELL DEATH AND DIFFERENTIATION

Functional imaging of proteases: recent advances in the design and application of substrate-based and activity-based probes

(2011) Laura E Edgington et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Eosinophil and neutrophil extracellular DNA traps in human allergic asthmatic airways

(2011) Ryszard Dworski et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Restoration of anti-Aspergillus defense by neutrophil extracellular traps in human chronic granulomatous disease after gene therapy is calprotectin-dependent

(2011) Matteo Bianchi et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Increased Levels of Leukocyte-Derived MMP-9 in Patients with Stable Angina Pectoris

(2011) Simon Jönsson et al.   PLoS One

Neutrophils Activate Plasmacytoid Dendritic Cells by Releasing Self-DNA-Peptide Complexes in Systemic Lupus Erythematosus

(2011) R. Lande et al.   Science Translational Medicine

Neutrophil extracellular trap cell death requires both autophagy and superoxide generation

(2010) Quinten Remijsen et al.   CELL RESEARCH

Neutrophil elastase and myeloperoxidase regulate the formation of neutrophil extracellular traps

(2010) Venizelos Papayannopoulos et al.   JOURNAL OF CELL BIOLOGY

Activation of the Raf-MEK-ERK pathway is required for neutrophil extracellular trap formation

(2010) Abdul Hakkim et al.   Nature Chemical Biology

Production of Extracellular Traps against Aspergillus fumigatus In Vitro and in Infected Lung Tissue Is Dependent on Invading Neutrophils and Influenced by Hydrophobin RodA

(2010) Sandra Bruns et al.   PLoS Pathogens

Caspase 1–independent activation of interleukin-1β in neutrophil-predominant inflammation

(2009) Monica Guma et al.   ARTHRITIS AND RHEUMATISM

Inflammatory arthritis in caspase 1 gene–deficient mice: Contribution of proteinase 3 to caspase 1–independent production of bioactive interleukin-1β

(2009) Leo A. B. Joosten et al.   ARTHRITIS AND RHEUMATISM

Netting neutrophils in autoimmune small-vessel vasculitis

(2009) Kai Kessenbrock et al.   NATURE MEDICINE

Improved visualization of protein consensus sequences by iceLogo

(2009) Niklaas Colaert et al.   NATURE METHODS

Neutrophil Extracellular Traps Contain Calprotectin, a Cytosolic Protein Complex Involved in Host Defense against Candida albicans

(2009) Constantin F. Urban et al.   PLoS Pathogens

Inhibition of a Secreted Glutamic Peptidase Prevents Growth of the FungusTalaromyces emersonii

(2008) Anthony J. O'Donoghue et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

In-depth Analysis of Tandem Mass Spectrometry Data from Disparate Instrument Types

(2008) Robert J. Chalkley et al.   MOLECULAR & CELLULAR PROTEOMICS

Proteome-derived, database-searchable peptide libraries for identifying protease cleavage sites

(2008) Oliver Schilling et al.   NATURE BIOTECHNOLOGY

Neutrophil elastase, proteinase 3 and cathepsin G: Physicochemical properties, activity and physiopathological functions

(2007) Brice Korkmaz et al.   BIOCHIMIE