Proteomics Analysis of Human Obesity Reveals the Epigenetic Factor HDAC4 as a Potential Target for Obesity

Upregulation of thrombospondin-1 expression by leptin in vascular smooth muscle cells via JAK2- and MAPK-dependent pathways

(2012) Ronaldo J. Chavez et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Class II Histone Deacetylases Downregulate GLUT4 Transcription in Response to Increased cAMP Signaling in Cultured Adipocytes and Fasting Mice

(2012) J. C. Weems et al.   DIABETES

Why exercise is an important component of risk reduction in obesity management

(2012) Rosemary A McGinnes et al.   MEDICAL JOURNAL OF AUSTRALIA

Uncovering Suitable Reference Proteins for Expression Studies in Human Adipose Tissue with Relevance to Obesity

(2012) Rafael Pérez-Pérez et al.   PLoS One

A Hormone-Dependent Module Regulating Energy Balance

(2011) Biao Wang et al.   CELL

Endoplasmic Reticulum Stress Inhibits STAT3-Dependent Suppression of Hepatic Gluconeogenesis via Dephosphorylation and Deacetylation

(2011) K. Kimura et al.   DIABETES

Specific Control of Pancreatic Endocrine β- and δ-Cell Mass by Class IIa Histone Deacetylases HDAC4, HDAC5, and HDAC9

(2011) Olivia Lenoir et al.   DIABETES

Lysine acetylation in obesity, diabetes and metabolic disease

(2011) Abishek Iyer et al.   IMMUNOLOGY AND CELL BIOLOGY

Histone Deacetylase 9 Is a Negative Regulator of Adipogenic Differentiation

(2011) Tapan K. Chatterjee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Quantitative Proteomic Analysis of the Adipocyte Plasma Membrane

(2011) Matthew J. Prior et al.   JOURNAL OF PROTEOME RESEARCH

Attenuated metabolism is a hallmark of obesity as revealed by comparative proteomic analysis of human omental adipose tissue

(2011) Rafael Pérez-Pérez et al.   Journal of Proteomics

Improved Recovery and Identification of Membrane Proteins from Rat Hepatic Cells using a Centrifugal Proteomic Reactor

(2011) Hu Zhou et al.   MOLECULAR & CELLULAR PROTEOMICS

HDAC-mediated deacetylation of NF-κB is critical for Schwann cell myelination

(2011) Ying Chen et al.   NATURE NEUROSCIENCE

A Genome-Wide Association Study on Obesity and Obesity-Related Traits

(2011) Kai Wang et al.   PLoS One

Thrombospondin1 Deficiency Reduces Obesity-Associated Inflammation and Improves Insulin Sensitivity in a Diet-Induced Obese Mouse Model

(2011) Yanzhang Li et al.   PLoS One

Histone deacetylases as regulators of inflammation and immunity

(2011) Melanie R. Shakespear et al.   TRENDS IN IMMUNOLOGY

Haploinsufficiency of HDAC4 Causes Brachydactyly Mental Retardation Syndrome, with Brachydactyly Type E, Developmental Delays, and Behavioral Problems

(2010) Stephen R. Williams et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Endoplasmic Reticulum Stress and the Inflammatory Basis of Metabolic Disease

(2010) Gökhan S. Hotamisligil   CELL

HDAC6 controls autophagosome maturation essential for ubiquitin-selective quality-control autophagy

(2010) Joo-Yong Lee et al.   EMBO JOURNAL

Genome-wide linkage and peak-wide association study of obesity-related quantitative traits in Caribbean Hispanics

(2010) Chuanhui Dong et al.   HUMAN GENETICS

Rai1 haploinsufficiency causes reduced Bdnf expression resulting in hyperphagia, obesity and altered fat distribution in mice and humans with no evidence of metabolic syndrome

(2010) Brooke Burns et al.   HUMAN MOLECULAR GENETICS

A DNAJB Chaperone Subfamily with HDAC-Dependent Activities Suppresses Toxic Protein Aggregation

(2010) Jurre Hageman et al.   MOLECULAR CELL

CPLA 1.0: an integrated database of protein lysine acetylation

(2010) Zexian Liu et al.   NUCLEIC ACIDS RESEARCH

Acetylation of Metabolic Enzymes Coordinates Carbon Source Utilization and Metabolic Flux

(2010) Q. Wang et al.   SCIENCE

The Role of JNK Proteins in Metabolism

(2010) S. N. Vallerie et al.   Science Translational Medicine

Prevalence of Overweight, Obesity, and Metabolic Syndrome Among Adult Kuwaitis: Results From Community-based National Survey

(2009) Ibrahim Al Rashdan et al.   ANGIOLOGY

Do low control response rates always affect the findings? Assessments of smoking and obesity in two Australian case-control studies of cancer

(2009) Nirmala Pandeya et al.   AUSTRALIAN AND NEW ZEALAND JOURNAL OF PUBLIC HEALTH

HDAC4 Represses Vascular Endothelial Growth Factor Expression in Chondrosarcoma by Modulating RUNX2 Activity

(2009) Xiaojuan Sun et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Exercise-induced histone modifications in human skeletal muscle

(2009) Sean L. McGee et al.   JOURNAL OF PHYSIOLOGY-LONDON

Differential Proteomics of Omental and Subcutaneous Adipose Tissue Reflects Their Unalike Biochemical and Metabolic Properties

(2009) Rafael Pérez-Pérez et al.   JOURNAL OF PROTEOME RESEARCH

NF- B Activation, Dependent on Acetylation/Deacetylation, Contributes to HIF-1 Activity and Migration of Bone Metastatic Breast Carcinoma Cells

(2009) P. Bendinelli et al.   MOLECULAR CANCER RESEARCH

Abdominal Obesity, Insulin Resistance, and the Metabolic Syndrome: Contribution of Physical Activity/Exercise

(2009) Robert Ross et al.   Obesity

HDAC4 Regulates Neuronal Survival in Normal and Diseased Retinas

(2009) B. Chen et al.   SCIENCE

Stress-Inducible Regulation of Heat Shock Factor 1 by the Deacetylase SIRT1

(2009) S. D. Westerheide et al.   SCIENCE

Lysine Acetylation Targets Protein Complexes and Co-Regulates Major Cellular Functions

(2009) C. Choudhary et al.   SCIENCE

Cellular conditioning with trichostatin A enhances the anti-stress response through up-regulation of HDAC4 and down-regulation of the IGF/Akt pathway

(2008) Fei Chu et al.   AGING CELL

Phosphorylation of IRS proteins, insulin action, and insulin resistance

(2008) Sigalit Boura-Halfon et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

A Redox-Dependent Pathway for Regulating Class II HDACs and Cardiac Hypertrophy

(2008) Tetsuro Ago et al.   CELL

Inflammation, heat shock proteins, and type 2 diabetes

(2008) Philip L. Hooper et al.   CELL STRESS & CHAPERONES

Cholestane-3β,5α,6β-triol-induced reactive oxygen species production promotes mitochondrial dysfunction in isolated mice liver mitochondria

(2008) Hongmei Liu et al.   CHEMICO-BIOLOGICAL INTERACTIONS

HDAC4 inhibits cell-cycle progression and protects neurons from cell death

(2008) Nazanin Majdzadeh et al.   Developmental Neurobiology

Emerging role of adipose tissue hypoxia in obesity and insulin resistance

(2008) J Ye   INTERNATIONAL JOURNAL OF OBESITY

Contribution of IL-6 to the Hsp72, Hsp25, and αβ-crystallin responses to inflammation and exercise training in mouse skeletal and cardiac muscle

(2008) Kimberly A. Huey et al.   JOURNAL OF APPLIED PHYSIOLOGY