Visualization and Quantification of APP Intracellular Domain-Mediated Nuclear Signaling by Bimolecular Fluorescence Complementation

Turnover of Amyloid Precursor Protein Family Members Determines Their Nuclear Signaling Capability

(2013) Manuel T. Gersbacher et al.   PLoS One

Bimolecular fluorescence complementation (BiFC): A 5-year update and future perspectives

(2012) Yutaka Kodama et al.   BIOTECHNIQUES

Alzheimer Mechanisms and Therapeutic Strategies

(2012) Yadong Huang et al.   CELL

AICD Nuclear Signaling and Its Possible Contribution to Alzheimers Disease

(2012) Uwe Konietzko   Current Alzheimer Research

Bimolecular Fluorescence Complementation: Illuminating Cellular Protein Interactions

(2012) S. Ventura   CURRENT MOLECULAR MEDICINE

The toxic Aβ oligomer and Alzheimer's disease: an emperor in need of clothes

(2012) Iryna Benilova et al.   NATURE NEUROSCIENCE

Alzheimer's Disease-Linked Mutations in Presenilin-1 Result in a Drastic Loss of Activity in Purified γ-Secretase Complexes

(2012) Matthias Cacquevel et al.   PLoS One

APP dimer formation is initiated in the endoplasmic reticulum and differs between APP isoforms

(2011) Simone Isbert et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Structural features of the KPI domain control APP dimerization, trafficking, and processing

(2011) Naouel Ben Khalifa et al.   FASEB JOURNAL

The physiology of the β-amyloid precursor protein intracellular domain AICD

(2011) Raphaëlle Pardossi-Piquard et al.   JOURNAL OF NEUROCHEMISTRY

APP is Phosphorylated by TrkA and Regulates NGF/TrkA Signaling

(2011) C. Matrone et al.   JOURNAL OF NEUROSCIENCE

The Transcriptionally Active Amyloid Precursor Protein (APP) Intracellular Domain Is Preferentially Produced from the 695 Isoform of APP in a β-Secretase-dependent Pathway

(2010) Nikolai D. Belyaev et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cell-type dependent modulation of Notch signaling by the amyloid precursor protein

(2010) Sun Young Oh et al.   JOURNAL OF NEUROCHEMISTRY

A Flow Cytometry-Based FRET Assay to Identify and Analyse Protein-Protein Interactions in Living Cells

(2010) Carina Banning et al.   PLoS One

Zooming into protein oligomerization in neurodegeneration using BiFC

(2010) Susana A. Gonçalves et al.   TRENDS IN BIOCHEMICAL SCIENCES

Nuclear signaling by the APP intracellular domain occurs predominantly through the amyloidogenic processing pathway

(2009) Z. V. Goodger et al.   JOURNAL OF CELL SCIENCE

The interactome of the amyloid β precursor protein family members is shaped by phosphorylation of their intracellular domains

(2009) Robert Tamayev et al.   Molecular Neurodegeneration

CHIP Targets Toxic α-Synuclein Oligomers for Degradation

(2008) Julie E. Tetzlaff et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Co-localization of the amyloid precursor protein and Notch intracellular domains in nuclear transcription factories

(2008) Uwe Konietzko et al.   NEUROBIOLOGY OF AGING

LRP1 modulates APP trafficking along early compartments of the secretory pathway

(2008) Elaine Waldron et al.   NEUROBIOLOGY OF DISEASE

Formation of Toxic Oligomeric α-Synuclein Species in Living Cells

(2008) Tiago Fleming Outeiro et al.   PLoS One

Study and selection of in vivo protein interactions by coupling bimolecular fluorescence complementation and flow cytometry

(2007) Montse Morell et al.   Nature Protocols