Article
Immunology
Marco Fonzo, Annamaria Nicolli, Stefano Maso, Lorenzo Carrer, Andrea Trevisan, Chiara Bertoncello
Summary: This study investigated the relationship between overweight/obesity and antibody persistence after vaccination against measles, mumps, rubella (MMR), and hepatitis B virus (HBV). The results showed that there was no significant association between lack of serologic protection and BMI for both HBV vaccine and each component of the MMR vaccine.
Review
Infectious Diseases
Julie Schenk, Steven Abrams, Heidi Theeten, Pierre Van Damme, Philippe Beutels, Niel Hens
Summary: This study conducted a systematic review and meta-analysis to estimate the seroconversion and waning rates of the measles, mumps, and rubella components of MMR vaccines. The results provide essential insights for improving the accuracy of mathematical and statistical modeling to predict and understand future outbreaks of measles, mumps, and rubella in countries with high vaccine uptake.
LANCET INFECTIOUS DISEASES
(2021)
Review
Medicine, General & Internal
Carlo Di Pietrantonj, Alessandro Rivetti, Pasquale Marchione, Maria Grazia Debalini, Vittorio Demicheli
Summary: The MMR vaccine is effective and safe in preventing measles, mumps, and rubella, with high efficacy rates. However, public debate over vaccine safety continues, highlighting the need for more evidence to support its use.
COCHRANE DATABASE OF SYSTEMATIC REVIEWS
(2021)
Article
Oncology
Zumama Khalid, Simona Coco, Nadir Ullah, Alessandra Pulliero, Katia Cortese, Serena Varesano, Andrea Orsi, Alberto Izzotti
Summary: This study evaluates the therapeutic effect of the MMR vaccine on cancer, specifically Glioblastoma (GBM). The results show significant reduction in viability of GBM cells after MMR treatment, suggesting the potential use of MMR vaccine in GBM therapy.
Article
Immunology
Maddalena Casale, Nicoletta Di Maio, Valentina Verde, Saverio Scianguetta, Maria Grazia Di Girolamo, Rita Tomeo, Domenico Roberti, Saverio Misso, Silverio Perrotta
Summary: This study investigated the impact of blood transfusions on the immunogenicity of the MMR vaccine, finding no significant difference in immune responses to measles, mumps, and rubella between transfusion-dependent and non-transfusion-dependent patients. Further larger studies are needed to assess the impact of chronic transfusions on vaccine response.
Article
Immunology
Mona Marin, Amy Parker Fiebelkorn, Daoling Bi, Laura A. Coleman, Janell Routh, Aaron T. Curns, Huong Q. McLean
Summary: The research found that the reported adverse events in young adults receiving a third measles-mumps-rubella (MMR) vaccine (MMR3) in a non-outbreak setting were mild and transient, indicating that MMR3 is safe and tolerable in this population.
CLINICAL INFECTIOUS DISEASES
(2021)
Review
Immunology
Florence Kauffmann, Catherine Heffernan, Francois Meurice, Martin O. C. Ota, Volker Vetter, Giacomo Casabona
Summary: The article reviews the challenges in controlling measles, mumps and rubella infections, mainly related to low immunization coverage and vaccine characteristics. Strategies to address these challenges include raising awareness of disease severity and vaccines impact, targeting high-risk population, improving vaccination access, setting up outbreak preparedness plans, and strengthening surveillance systems.
EXPERT REVIEW OF VACCINES
(2021)
Article
Immunology
Kyoko Mukasa, Tamie Sugawara, Yoichi Okutomi
Summary: This study investigated the vaccine and infection histories of nursery teachers and found higher susceptibility for measles, rubella, varicella, and mumps. Age was found to influence disease susceptibility, with different age groups showing different proportions of susceptibility.
Article
Public, Environmental & Occupational Health
Neuberger Ami, Nadir Eyal, Biber Asaf, Avni Chen, Brom Adi, Attias Drorit, Petersiel Neta, Dallashi Hajar, Rakedzon Stav, Schwartz Eli
Summary: A prospective cohort study on 785 adult travellers who were incompletely vaccinated during a measles outbreak in Europe found that 25.2% reported adverse events post-vaccination. Females had higher rates of reported adverse events compared to males, while there were no significant differences in adverse event rates between the MMR and MMRV vaccines.
JOURNAL OF TRAVEL MEDICINE
(2021)
Article
Infectious Diseases
Nadhikala Muthiah, Geethani Galagoda, Shiroma Handunnetti, Sudath Peiris, Sisira Pathirana
Summary: The study found that maternal transfer of antibodies provides protection to infants, especially until they reach 6-7 months old. Mothers with natural infections had higher antibody levels compared to vaccinated mothers, resulting in a higher level of maternal transfer.
INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES
(2021)
Article
Immunology
Nicola Frau, Federico Meloni, Jacopo Fostinelli, Laura Portas, Igor Portoghese, Emma Sala, Ilaria Pilia, Luigi Isaia Lecca, Giuseppe De Palma, Marcello Campagna
Summary: This study assessed the immunity against measles, mumps, rubella, and varicella viruses in a cohort of female school workers, revealing a significant proportion of workers susceptible to the diseases, especially showing decreased immunity against mumps and rubella. The findings underscore the importance of proper health surveillance and immunological controls in school workers, particularly for females, to contain the risk of vaccine-preventable diseases effectively.
Article
Immunology
Epiphane Kolla, Alain Weill, David Desplas, Laura Semenzato, Mahmoud Zureik, Lamiae Grimaldi
Summary: This study aimed to evaluate the effect of live attenuated MMR vaccines on the risk of being hospitalized for COVID-19 in children. The results showed that children exposed to MMR vaccines did not have a decreased risk of COVID-19 hospitalization compared to those not exposed.
Article
Immunology
Wiebke Schaefer, Tammo Reinders, Tania Schink
Summary: Studies have shown that there is an increased risk of febrile convulsions after the first immunization with the quadrivalent measles-mumps-rubella-varicella vaccine compared to other vaccination options. However, this increased risk is not observed after the second dose of the vaccine, regardless of factors such as age, sex, history of febrile convulsions, or type of the first dose vaccine.
Article
Public, Environmental & Occupational Health
Haley Comfort, Riyadh K. Lafta, Abraham D. Flaxman, Amy Hagopian, Herbert C. Duber
Summary: This analysis explores the incidence of measles, mumps, and rubella at the governorate-level in Iraq between 2001 and 2016, and investigates the relationship between incidence and the number of persons of concern. The study reveals significant variability in disease incidence among different governorates, with vaccination coverage and migration of persons of concern playing a role in measles incidence. However, these factors do not show a significant influence on mumps and rubella incidence.
FRONTIERS IN PUBLIC HEALTH
(2022)
Article
Environmental Sciences
Chunghyeon Oh, Eric Rafai, Yinseo Cho, Damin Jun, Seungman Cha
Summary: This study estimated the benefits and costs of introducing a mumps vaccination program in Fiji, and found that it is cost-effective from both the taxpayer and societal perspectives. Urgent introduction of MMR vaccination is recommended.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2022)
Article
Public, Environmental & Occupational Health
Yusuke Kamata, Kageaki Tojinbara, Katie Hampson, Kohei Makita
Summary: This study evaluated the effectiveness of rabies control policies in Japan by analyzing historical data from the Kanto region. The results demonstrate that coordinated control policies involving dog vaccination and management of free-roaming dogs were highly effective in eliminating rabies.
ZOONOSES AND PUBLIC HEALTH
(2023)
Article
Immunology
C. Edson Utazi, Justice M. K. Aheto, Adelle Wigley, Natalia Tejedor-Garavito, Amy Bonnie, Christopher C. Nnanatu, John Wagai, Cheryl Williams, Hamidreza Setayesh, Andrew J. Tatem, Felicity T. Cutts
Summary: Geographically precise identification and targeting of populations at risk of vaccine-preventable diseases has gained renewed attention. District level estimates of vaccination coverage and zero-dose prevalence provide valuable evidence for evaluating vaccination strategies and identifying missed communities.
Article
Medicine, General & Internal
Winfred Dotse-Gborgbortsi, Andrew J. Tatem, Zoe Matthews, Victor A. Alegana, Anthony Ofosu, Jim A. Wright
Summary: The study investigates the impact of maternal health service quality and travel times to health facilities on birthing service utilization in the Eastern Region of Ghana. The findings reveal a significant decrease in utilization rate as travel time increases. Higher quality of maternal health services has a larger positive effect on utilization rates compared to service proximity. To increase birthing service utilization in Ghana, it is crucial to establish higher quality health facilities closer to women, particularly in rural areas.
Article
Environmental Sciences
Sarchil Hama Qader, Chigozie Edson Utazi, Rhorom Priyatikanto, Peshawa Najmaddin, Emad Omer Hama-Ali, Nabaz R. Khwarahm, Andrew J. Tatem, Jadu Dash
Summary: This study demonstrates the value of using Sentinel-2 satellite sensor-derived data and environmental covariates for accurately modeling and predicting wheat crop yield in arid and semi-arid regions. The method can potentially increase the availability of agricultural statistics in conflict zones.
SCIENCE OF THE TOTAL ENVIRONMENT
(2023)
Article
Biochemical Research Methods
David J. J. Haw, Matthew Biggerstaff, Pragati Prasad, Joseph Walker, Bryan Grenfell, Nimalan Arinaminpathy
Summary: Influenza pandemics often occur in multiple waves, with an initial wave followed by a resurgence accompanied by the annual flu season. This study examines whether data from the initial wave can be used to inform the need for non-pharmaceutical measures in subsequent waves. By analyzing data from the 2009 H1N1 pandemic in 10 states in the USA, the researchers developed a mathematical model to predict hospitalizations during the fall wave based on the spring wave. The model showed reasonable agreement with the actual data, suggesting that preemptive measures such as delaying school openings can be determined using this approach.
PLOS COMPUTATIONAL BIOLOGY
(2023)
Article
Biology
Wha-Eum Lee, Sang Woo Park, Daniel M. Weinberger, Donald Olson, Lone Simonsen, Bryan T. Grenfell, Cecile Viboud
Summary: Excess mortality studies provide important information on the health burden of pandemics and other large-scale events. This study separates the direct impact of SARS-CoV-2 infection on mortality from the indirect consequences of the pandemic in the United States using time series approaches. The results indicate that the largest consequences of the COVID-19 pandemic are due to the direct impact of SARS-CoV-2 infections, but the secondary impacts dominate among younger age groups and in mortality from external causes.
Article
Multidisciplinary Sciences
Carla Pezzulo, Natalia Tejedor-Garavito, Ho Man Theophilus Chan, Ilda Dreoni, David Kerr, Samik Ghosh, Amy Bonnie, Maksym Bondarenko, Mihretab Salasibew, Andrew. J. J. Tatem
Summary: Understanding the distribution of health and development indicators at fine scale and subnational level is crucial for targeted resource allocation and efficient planning. We created an open access collection of high resolution gridded and district level datasets for India, providing spatially detailed data to support policy-making.
Article
Demography
Douglas R. Leasure, Ridhi Kashyap, Francesco Rampazzo, Claire A. Dooley, Benjamin Elbers, Maksym Bondarenko, Mark Verhagen, Arun Frey, Jiani Yan, Evelina T. Akimova, Masoomali Fatehkia, Robert Trigwell, Andrew J. Tatem, Ingmar Weber, Melinda C. Mills
Summary: In times of crisis, real-time data mapping population displacements are invaluable for targeted humanitarian response. We leveraged social media data from Facebook's advertising platform in combination with preconflict population data to build a real-time monitoring system to estimate subnational population sizes every day disaggregated by age and sex. The use of social media provided one of the only quantitative estimates of internal displacement in the conflict setting in virtual real time, revealing four distinct displacement patterns.
POPULATION AND DEVELOPMENT REVIEW
(2023)
Article
Demography
Lina Maria Sanchez-Cespedes, Douglas Ryan Leasure, Natalia Tejedor-Garavito, Glenn Harry Amaya Cruz, Gustavo Adolfo Garcia Velez, Andryu Enrique Mendoza, Yenny Andrea Marin Salazar, Thomas Esch, Andrew J. Tatem, Mariana Ospina Bohorquez
Summary: Effective government services rely on accurate population numbers, yet census enumeration can be challenging in remote and conflict-affected regions. In Colombia, community representatives estimated dwelling and population numbers through social cartography workshops. By combining this data with remote sensing and geospatial information, we developed hierarchical Bayesian models to estimate building and population sizes. Our results showed that incorporating both community knowledge and remotely sensed building data in the Combination model yielded the highest overall accuracy for population estimation.
POPULATION STUDIES-A JOURNAL OF DEMOGRAPHY
(2023)
Article
Infectious Diseases
Dongni Wu, Hong Zhu, Lun Wan, Juan Zhang, Wen Lin, Lingcong Sun, Huaxun Zhang, Si Liu, Eimear Cleary, Andrew J. Tatem, Jing Xia, Shengjie Lai
Summary: This study investigated the epidemiological changes in P. vivax and P. falciparum malaria in Hubei Province. It found that imported cases of P. falciparum malaria have been increasing, accounting for 78.81% of all cases in 2019.
Letter
Biochemistry & Molecular Biology
Alexander Shaw, Catherine Troman, Joyce Odeke J. Akello, Kathleen O'Reilly, Jillian Gauld, Stephanie Grow, Nicholas Grassly, Duncan Steele, David Blazes, Supriya Kumar, Environmental Surveillance Working Group
Article
Multidisciplinary Sciences
Yong Ge, Xilin Wu, Wenbin Zhang, Xiaoli Wang, Die Zhang, Jianghao Wang, Haiyan Liu, Zhoupeng Ren, Nick W. Ruktanonchai, Corrine W. Ruktanonchai, Eimear Cleary, Yongcheng Yao, Amy Wesolowski, Derek A. T. Cummings, Zhongjie Li, Andrew J. Tatem, Shengjie Lai
Summary: Targeted public health interventions are crucial in preventing pandemics. China's efforts in implementing strict zero-COVID measures have effectively contained outbreaks caused by different SARS-CoV-2 variants. Social distancing measures, face masks, and contact tracing were found to be the most effective interventions, with their effectiveness varying during different phases of the outbreaks. Our findings provide quantitative evidence on the effects of public-health measures for controlling emerging contagions in different contexts.
NATURE COMMUNICATIONS
(2023)
Article
Environmental Sciences
Grant Rogers, Patrycja Koper, Cori Ruktanonchai, Nick Ruktanonchai, Edson Utazi, Dorothea Woods, Alexander Cunningham, Andrew J. Tatem, Jessica Steele, Shengjie Lai, Alessandro Sorichetta
Summary: Mobile phone data is widely used to measure population movements, but it is not readily available due to commercial restrictions and privacy concerns. Night-time light imagery can be used as a substitute, but its reliability varies in different areas. In rural areas, there is a strong correlation between night-time light and mobile phone data, while in urban areas, the correlation is weaker.
Article
Construction & Building Technology
Haiyan Liu, Jianghao Wang, Jian Liu, Yong Ge, Xiaoli Wang, Chi Zhang, Eimear Cleary, Nick W. Ruktanonchai, Corrine W. Ruktanonchai, Yongcheng Yao, Amy Wesolowski, Xin Lu, Andrew J. Tatem, Xuemei Bai, Shengjie Lai
Summary: This study proposes a framework for data-driven analysis on mobility resilience, revealing the compound effects of COVID-19 and extreme weather events on mobility recovery in cities with different socioeconomic contexts. The study finds that high temperatures and abnormal precipitation levels increase the risk of reduced mobility below the pre-pandemic baseline during outbreaks. These compound impacts are more severe in cities with high population density and low GDP levels.
SUSTAINABLE CITIES AND SOCIETY
(2023)
Article
Public, Environmental & Occupational Health
Duah Dwomoh, Samuel Iddi, Seth Kwaku Afagbedzi, Natalia Tejedor-Garavito, Winfred Dotse-Gborgbortsi, Jim Wright, Andrew J. Tatem, Kristine Nilsen
Summary: The study assessed the disparities in maternal, neonatal, and child health service utilization between slum and non-slum districts in Ghana. The findings reveal a significant decline in vaccination coverage and antenatal care attendance in slum districts, while skilled birth delivery and postnatal care were higher in urban slum areas compared to non-urban slum areas.
JOURNAL OF URBAN HEALTH-BULLETIN OF THE NEW YORK ACADEMY OF MEDICINE
(2023)
