Comparative Analysis of TGF-β/Smad Signaling Dependent Cytostasis in Human Hepatocellular Carcinoma Cell Lines

Overexpression of Smad proteins, especially Smad7, in oral epithelial dysplasias

(2012) Yuk-Kwan Chen et al.   Clinical Oral Investigations

Hepatic stem cells and transforming growth factor β in hepatocellular carcinoma

(2012) Avijit Majumdar et al.   Nature Reviews Gastroenterology & Hepatology

Transforming Growth Factor Beta 1 Overexpression Is Closely Related to Invasiveness of Hepatocellular Carcinoma

(2012) Danbi Lee et al.   ONCOLOGY

Smad phosphoisoform signaling specificity: the right place at the right time

(2011) Koichi Matsuzaki   CARCINOGENESIS

Molecular Pathogenesis of Hepatocellular Carcinoma: Altering Transforming Growth Factor-β Signaling in Hepatocarcinogenesis

(2011) Ken Yamazaki et al.   DIGESTIVE DISEASES

Alterations in the Smad pathway in human cancers

(2011) Debangshu Samanta   Frontiers in Bioscience-Landmark

Mature hepatocytes exhibit unexpected plasticity by direct dedifferentiation into liver progenitor cells in culture

(2011) Yixin Chen et al.   HEPATOLOGY

Epithelial and mesenchymal phenotypic switchings modulate cell motility in metastasis

(2010) Alan Wells   Frontiers in Bioscience-Landmark

Transcription factors ETF, E2F, and SP-1 are involved in cytokine-independent proliferation of murine hepatocytes

(2010) Sebastian Zellmer et al.   HEPATOLOGY

Dissecting the effect of targeting the epidermal growth factor receptor on TGF-β-induced-apoptosis in human hepatocellular carcinoma cells

(2010) Laia Caja et al.   JOURNAL OF HEPATOLOGY

Distinct role of endocytosis for Smad and non-Smad TGF-β signaling regulation in hepatocytes

(2010) Christoph Meyer et al.   JOURNAL OF HEPATOLOGY

Reduced transforming growth factor-β receptor II expression in hepatocellular carcinoma correlates with intrahepatic metastasis

(2010) Takao Mamiya et al.   LABORATORY INVESTIGATION

Overactivation of the MEK/ERK Pathway in Liver Tumor Cells Confers Resistance to TGF- -Induced Cell Death through Impairing Up-regulation of the NADPH Oxidase NOX4

(2009) L. Caja et al.   CANCER RESEARCH

Hepatitis B virus X protein shifts human hepatic transforming growth factor (TGF)-β signaling from tumor suppression to oncogenesis in early chronic hepatitis B

(2009) Miki Murata et al.   HEPATOLOGY

Extracellular matrix modulates sensitivity of hepatocytes to fibroblastoid dedifferentiation and transforming growth factor β-induced apoptosis

(2009) Patricio Godoy et al.   HEPATOLOGY

Inhibition of c-Jun NH2-terminal kinase switches Smad3 signaling from oncogenesis to tumor- suppression in rat hepatocellular carcinoma

(2009) Hiromitsu Nagata et al.   HEPATOLOGY

Down-regulation of connective tissue growth factor by inhibition of transforming growth factor β blocks the tumor-stroma cross-talk and tumor progression in hepatocellular carcinoma

(2009) Antonio Mazzocca et al.   HEPATOLOGY

Targeting heat shock protein 90 with non-quinone inhibitors: A novel chemotherapeutic approach in human hepatocellular carcinoma

(2009) Marco Breinig et al.   HEPATOLOGY

TGFβ in Cancer

(2008) Joan Massagué   CELL

Hepatocyte-Specific Smad7 Expression Attenuates TGF-β–Mediated Fibrogenesis and Protects Against Liver Damage

(2008) Steven Dooley et al.   GASTROENTEROLOGY

Diagnosis and Treatment of Hepatocellular Carcinoma

(2008) Hashem B. El-Serag et al.   GASTROENTEROLOGY

Liver stem cells and hepatocellular carcinoma

(2008) Lopa Mishra et al.   HEPATOLOGY

Transforming growth factor-β gene expression signature in mouse hepatocytes predicts clinical outcome in human cancer

(2008) Cédric Coulouarn et al.   HEPATOLOGY