Mutation of the Fiber Shaft Heparan Sulphate Binding Site of a 5/3 Chimeric Adenovirus Reduces Liver Tropism

Immune Response Is an Important Aspect of the Antitumor Effect Produced by a CD40L-Encoding Oncolytic Adenovirus

(2012) I. Diaconu et al.   CANCER RESEARCH

A New Human DSG2-Transgenic Mouse Model for Studying the Tropism and Pathology of Human Adenoviruses

(2012) H. Wang et al.   JOURNAL OF VIROLOGY

Advances and Future Challenges in Adenoviral Vector Pharmacology and Targeting

(2011) Reeti Khare et al.   CURRENT GENE THERAPY

Coagulation factor X mediates adenovirus type 5 liver gene transfer in non-human primates (Microcebus murinus)

(2011) R Alba et al.   GENE THERAPY

Avidity Binding of Human Adenovirus Serotypes 3 and 7 to the Membrane Cofactor CD46 Triggers Infection

(2011) H. V. Trinh et al.   JOURNAL OF VIROLOGY

Real-Time Dynamic Imaging of Virus Distribution In Vivo

(2011) Sean E. Hofherr et al.   PLoS One

Cell Entry and Trafficking of Human Adenovirus Bound to Blood Factor X Is Determined by the Fiber Serotype and Not Hexon:Heparan Sulfate Interaction

(2011) Stéphanie Corjon et al.   PLoS One

Biodistribution and retargeting of FX-binding ablated adenovirus serotype 5 vectors

(2010) R. Alba et al.   BLOOD

Desmoglein 2 is a receptor for adenovirus serotypes 3, 7, 11 and 14

(2010) Hongjie Wang et al.   NATURE MEDICINE

Increasing the Efficacy of Oncolytic Adenovirus Vectors

(2010) Karoly Toth et al.   Viruses-Basel

Identification of coagulation factor (F)X binding sites on the adenovirus serotype 5 hexon: effect of mutagenesis on FX interactions and gene transfer

(2009) R. Alba et al.   BLOOD

Replacement of Adenovirus Type 5 Fiber Shaft Heparan Sulfate Proteoglycan-Binding Domain with RGD for Improved Tumor Infectivity and Targeting

(2009) Neus Bayo-Puxan et al.   HUMAN GENE THERAPY

Oncolytic virus therapy for prostate cancer

(2009) Hiroshi Fukuhara et al.   INTERNATIONAL JOURNAL OF UROLOGY

Systemic adenoviral gene delivery to orthotopic murine breast tumors with ablation of coagulation factors, thrombocytes and Kupffer cells

(2009) Anniina Koski et al.   JOURNAL OF GENE MEDICINE

Macrophage Depletion Combined with Anticoagulant Therapy Increases Therapeutic Window of Systemic Treatment with Oncolytic Adenovirus

(2008) E. V. Shashkova et al.   CANCER RESEARCH

Adenovirus Serotype 5 Hexon Mediates Liver Gene Transfer

(2008) Simon N. Waddington et al.   CELL

Coagulation Factors Determine Tumor Transduction In Vivo

(2008) Marta Gimenez-Alejandre et al.   HUMAN GENE THERAPY

Role of Cellular Heparan Sulfate Proteoglycans in Infection of Human Adenovirus Serotype 3 and 35

(2008) Sebastian Tuve et al.   PLoS Pathogens