Article
Agriculture, Dairy & Animal Science
K. Kaseja, S. Mucha, J. Yates, E. Smith, G. Banos, J. Conington
Summary: This study investigated the genetic background of health and production traits in the UK Texel sheep population using phenotypic and SNP data. Results identified significant SNPs associated with birth weight, weaning weight, and scan weight. The study also found other SNPs related to animal health and production traits. The results suggest that these traits have a complex genetic architecture.
Article
Agriculture, Dairy & Animal Science
M. Serrano, M. Ramon, J. H. Calvo, M. A. Jimenez, F. Freire, J. M. Vazquez, J. J. Arranz
Summary: Sperm quality traits play a crucial role in the efficiency of artificial insemination centers and the fertility of rams, with traditional genetic selection being inefficient in improving these traits. A genome-wide association study identified candidate genes associated with sperm traits, which could be used in marker-assisted selection to enhance the sperm characteristics of Assaf rams and AI center efficiency.
Article
Agriculture, Dairy & Animal Science
Anna Maria Sutera, Rosalia Di Gerlando, Salvatore Mastrangelo, Maria Teresa Sardina, Enrico D'Alessandro, Baldassare Portolano, Marco Tolone
Summary: This study conducted a GWAS for milk production traits in Valle del Belice sheep and identified 23 significant SNPs associated with milk yield, fat and protein percentage and yield. These SNPs provide useful information for understanding the genetic mechanisms underlying milk production and quality traits in dairy sheep.
ITALIAN JOURNAL OF ANIMAL SCIENCE
(2021)
Article
Agriculture, Dairy & Animal Science
Md Azizul Haque, Mohammad Zahangir Alam, Asif Iqbal, Yun-Mi Lee, Chang-Gwon Dang, Jong-Joo Kim
Summary: Holstein has been the most widely used dairy cattle breed in the Korean Peninsula since its introduction in 1885. A genome-wide association study (GWAS) was conducted to identify the genes associated with body conformation traits in the Korean Holstein population, and 24 significant SNPs were identified. The study provides insights into the genetic basis of body conformation traits and paves the way for future breeding strategies in dairy cattle.
Review
Veterinary Sciences
Muhammad Zahoor Khan, Yulin Ma, Jiaying Ma, Jianxin Xiao, Yue Liu, Shuai Liu, Adnan Khan, Ibrar Muhammad Khan, Zhijun Cao
Summary: This article highlights the role of DGAT1 in milk and meat production traits in cattle, buffalo, sheep, and goats, as well as the potential future contributions of DGAT1 in these species. The study also emphasizes the existing gap in research on the association of DGAT1 with meat production traits in cattle and the absence of studies on buffalo, calling for further research to address this significant gap.
FRONTIERS IN VETERINARY SCIENCE
(2021)
Article
Genetics & Heredity
Wenwu Xu, Zhenzhen Wang, Yuanqi Qu, Qingyi Li, Yong Tian, Li Chen, Jianhong Tang, Chengfeng Li, Guoqin Li, Junda Shen, Zhengrong Tao, Yongqing Cao, Tao Zeng, Lizhi Lu
Summary: The study identified genomic regions and candidate genes associated with age at first egg and egg production in a Shaoxing duck population using GWAS and haplotype-sharing analysis. Multiple genes were found to be associated with age at first egg and egg production at different time points, providing potential candidate genes and haplotypes to improve egg production performance in laying ducks.
FRONTIERS IN GENETICS
(2022)
Article
Agriculture, Dairy & Animal Science
Onur Yilmaz, Mehmet Kizilaslan, Yunus Arzik, Sedat Behrem, Nezih Ata, Orhan Karaca, Cengiz Elmaci, Ibrahim Cemal
Summary: Sheep play a crucial role in global food security, with their growth traits and carcass composition traits being essential indicators of meat yield. GWAS analysis in Esme sheep identified several candidate genes associated with these traits, offering insights into the molecular mechanisms underlying growth and carcass composition traits. These findings have implications for faster genetic improvement and targeted SNP designs.
JOURNAL OF ANIMAL BREEDING AND GENETICS
(2022)
Article
Agriculture, Dairy & Animal Science
Ruonan Li, Yuhetian Zhao, Benmeng Liang, Yabin Pu, Lin Jiang, Yuehui Ma
Summary: In this study, whole-genome sequences were analyzed to investigate the genetic signatures of milk production in dairy sheep, and 553 genes were found to be related to milk production. The validation experiment showed that the FCGR3A gene has a significant negative relationship with milk production. This study provides a basis for further research on the genetic mechanism underlying milk production traits in sheep.
Article
Agriculture, Dairy & Animal Science
Herman Alberto Revelo, Diana Lopez-Alvarez, Yineth Alexandra Palacios, Oscar David Vergara, Moris Bustamante Yanez, Manuel Fernando Ariza, Susan Lorena Castro Molina, Yurany Ortiz Sanchez, Luz angela Alvarez
Summary: This study conducted a genome-wide association study on meat quality traits using GWAS and identified 11 candidate genes associated with water-holding capacity. It provided a baseline for future GWAS research on meat quality traits in Colombian hair sheep.
TROPICAL ANIMAL HEALTH AND PRODUCTION
(2023)
Article
Plant Sciences
Yafang Fu, Jianchao Liu, Zhenqing Xia, Qi Wang, Shibo Zhang, Guixin Zhang, Haidong Lu
Summary: Nitrogen is an important factor affecting maize root morphological construction and growth development. In this study, root and shoot growth of 124 maize inbred lines were evaluated under normal nitrogen and low nitrogen treatments. A genome-wide association study was performed, and 185 significant SNPs were identified, along with four important candidate genes. These findings provide genetic resources for the genetic improvement of maize root traits.
Article
Multidisciplinary Sciences
Ming-Yue Zhang, Cheng Xue, Hongju Hu, Jiaming Li, Yongsong Xue, Runze Wang, Jing Fan, Cheng Zou, Shutian Tao, Mengfan Qin, Bing Bai, Xiaolong Li, Chao Gu, Shan Wu, Xu Chen, Guangyan Yang, Yueyuan Liu, Manyi Sun, Zhangjun Fei, Shaoling Zhang, Jun Wu
Summary: This study conducted genome-wide association studies to identify loci associated with fruit quality and phenological traits in pear, revealing continuous selection pressure on important traits during breeding. The candidate gene PbrSTONE was functionally verified to play a key role in regulating stone cell formation, a critical fruit quality trait in pear.
NATURE COMMUNICATIONS
(2021)
Article
Biotechnology & Applied Microbiology
Hongchang Zhao, Tingting Guo, Zengkui Lu, Jianbin Liu, Shaohua Zhu, Guoyan Qiao, Mei Han, Chao Yuan, Tianxiang Wang, Fanwen Li, Yajun Zhang, Fujun Hou, Yaojing Yue, Bohui Yang
Summary: This study conducted re-sequencing of 460 sheep from four different fine-wool sheep breeds and identified candidate genes and SNPs associated with wool traits. These findings provide a significant theoretical basis for breeding fine-wool sheep.
Article
Agriculture, Dairy & Animal Science
Guangliang Gao, Keshan Zhang, Ping Huang, Xianzhi Zhao, Qin Li, Youhui Xie, Chunhui Yin, Jing Li, Zhen Wang, Hang Zhong, Jiajia Xue, Zhuping Chen, Xianwen Wu, Qigui Wang
Summary: This study conducted a genome-wide association study to screen and identify single nucleotide polymorphisms (SNPs) associated with geese meat quality traits. The results revealed 43 potentially significant SNPs associated with these traits, as well as 28 annotated genes as potential candidate genes. Enrichment analysis showed potential pathway enrichment in protein digestion and absorption and glycolipid metabolism. This study provides novel genetic markers and candidate genes for marker-assisted selection and lays the foundation for understanding the genetic basis of goose meat quality traits.
Article
Mathematical & Computational Biology
Yang Li, Fan Wang, Mengyun Wu, Shuangge Ma
Summary: The integrative functional linear model proposed in this study effectively addresses the challenges posed by high-dimensional SNP data and correlations among multiple traits in GWAS. It demonstrates satisfactory performance in the identification of disease-associated genetic variants and provides biologically meaningful findings in the analysis of type 2 diabetes data.
Article
Multidisciplinary Sciences
Yoshinobu Uemoto, Kasumi Ichinoseki, Toshimi Matsumoto, Nozomi Oka, Hironori Takamori, Hiroshi Kadowaki, Chihiro Kojima-Shibata, Eisaku Suzuki, Toshihiro Okamura, Hisashi Aso, Haruki Kitazawa, Masahiro Satoh, Hirohide Uenishi, Keiichi Suzuki
Summary: This study identified novel quantitative trait loci (QTL) related to various production, respiratory disease, and immune-related traits in Landrace pigs through genotyping and genome-wide association studies. Most of the detected QTL regions were novel with potential candidate genes. When examining pleiotropic QTL across traits, only a few regions overlapped, indicating that many regions independently influenced traits.
SCIENTIFIC REPORTS
(2021)
