Molecular Modeling Studies of the Novel Inhibitors of DNA Methyltransferases SGI-1027 and CBC12: Implications for the Mechanism of Inhibition of DNMTs

Molecular Modeling and Virtual Screening of DNA Methyltransferase Inhibitors

(2013) Jose L. Medina-Franco et al.   CURRENT PHARMACEUTICAL DESIGN

DNA methylation inhibitors in cancer: Recent and future approaches

(2012) Christina Gros et al.   BIOCHIMIE

Towards the Chemoinformatic-Based Identification of DNA Methyltransferase Inhibitors: 2D- and 3D-Similarity Profile of Screening Libraries

(2012) Jakyung Yoo et al.   Current Computer-Aided Drug Design

Inhibitors of DNA Methyltransferases: Insights from Computational Studies

(2012) J. Yoo et al.   CURRENT MEDICINAL CHEMISTRY

Rapid Synthesis of New DNMT Inhibitors Derivatives of Procainamide

(2011) Ludovic Halby et al.   CHEMBIOCHEM

Homology modeling, docking and structure-based pharmacophore of inhibitors of DNA methyltransferase

(2011) Jakyung Yoo et al.   JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN

Synthesis and Biochemical Evaluation of Δ2-Isoxazoline Derivatives as DNA Methyltransferase 1 Inhibitors

(2011) Sabrina Castellano et al.   JOURNAL OF MEDICINAL CHEMISTRY

Trimethylaurintricarboxylic acid inhibits human DNA methyltransferase 1: insights from enzymatic and molecular modeling studies

(2011) Jakyung Yoo et al.   JOURNAL OF MOLECULAR MODELING

Epigenetic cancer therapy: rationales, targets and drugs

(2011) M Rius et al.   ONCOGENE

Preference by Exclusion

(2011) L. A. Godley et al.   SCIENCE

Small molecules DNA methyltransferases inhibitors

(2011) Nadine Martinet et al.   MedChemComm

Structure and Function of Mammalian DNA Methyltransferases

(2010) Renata Zofia Jurkowska et al.   CHEMBIOCHEM

Structure of DNMT1-DNA Complex Reveals a Role for Autoinhibition in Maintenance DNA Methylation

(2010) J. Song et al.   SCIENCE

Novel and selective DNA methyltransferase inhibitors: Docking-based virtual screening and experimental evaluation

(2009) Dirk Kuck et al.   BIOORGANIC & MEDICINAL CHEMISTRY

A New Class of Quinoline-Based DNA Hypomethylating Agents Reactivates Tumor Suppressor Genes by Blocking DNA Methyltransferase 1 Activity and Inducing Its Degradation

(2009) J. Datta et al.   CANCER RESEARCH

CXXC Domain of Human DNMT1 Is Essential for Enzymatic Activity

(2008) Mihika Pradhan et al.   BIOCHEMISTRY

Modes of action of the DNA methyltransferase inhibitors azacytidine and decitabine

(2008) Carlo Stresemann et al.   INTERNATIONAL JOURNAL OF CANCER

Mammalian DNA Methyltransferases: A Structural Perspective

(2008) Xiaodong Cheng et al.   STRUCTURE