Group II Metabotropic Glutamate Receptor Agonist LY379268 Regulates AMPA Receptor Trafficking in Prefrontal Cortical Neurons

mRNA Decay Proteins Are Targeted to poly(A)+ RNA and dsRNA-Containing Cytoplasmic Foci That Resemble P-Bodies in Entamoeba histolytica

(2012) Itzel López-Rosas et al.   PLoS One

A practical guide to evaluating colocalization in biological microscopy

(2011) Kenneth W. Dunn et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

A Multicenter, Inpatient, Phase 2, Double-Blind, Placebo-Controlled Dose-Ranging Study of LY2140023 Monohydrate in Patients With DSM-IV Schizophrenia

(2011) Bruce J. Kinon et al.   JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY

Study of Novel Selective mGlu2 Agonist in the Temporo-Ammonic Input to CA1 Neurons Reveals Reduced mGlu2 Receptor Expression in a Wistar Substrain with an Anxiety-Like Phenotype

(2011) L. Ceolin et al.   JOURNAL OF NEUROSCIENCE

mGluR2/3 agonist LY379268, by enhancing the production of GDNF, induces a time-related phosphorylation of RET receptor and intracellular signaling Erk1/2 in mouse striatum

(2011) Valentina Di Liberto et al.   NEUROPHARMACOLOGY

Group II metabotropic glutamate receptor agonists and positive allosteric modulators as novel treatments for schizophrenia

(2011) Matthew J. Fell et al.   NEUROPHARMACOLOGY

Fractionation of Spatial Memory in GRM2/3 (mGlu2/mGlu3) Double Knockout Mice Reveals a Role for Group II Metabotropic Glutamate Receptors at the Interface Between Arousal and Cognition

(2011) Louisa Lyon et al.   NEUROPSYCHOPHARMACOLOGY

Group II Metabotropic Glutamate Receptor Agonist Ameliorates MK801-Induced Dysfunction of NMDA Receptors via the Akt/GSK-3β Pathway in Adult Rat Prefrontal Cortex

(2011) Dong Xi et al.   NEUROPSYCHOPHARMACOLOGY

Translating Glutamate: From Pathophysiology to Treatment

(2011) D. C. Javitt et al.   Science Translational Medicine

Developing treatments for impaired cognition in schizophrenia

(2011) Michael J. Minzenberg et al.   TRENDS IN COGNITIVE SCIENCES

Routes, destinations and delays: recent advances in AMPA receptor trafficking

(2011) Jeremy M. Henley et al.   TRENDS IN NEUROSCIENCES

Metabotropic Glutamate Receptors: Physiology, Pharmacology, and Disease

(2010) Colleen M. Niswender et al.   Annual Review of Pharmacology and Toxicology

Effects of metabotropic glutamate receptor 2/3 agonism and antagonism on schizophrenia-like cognitive deficits induced by phencyclidine in rats

(2010) Nurith Amitai et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Regulation of AMPA Receptor Trafficking and Function by Glycogen Synthase Kinase 3

(2010) Jing Wei et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Postsynaptic and Presynaptic Group II Metabotropic Glutamate Receptor Activation Reduces Neuronal Excitability in Rat Midline Paraventricular Thalamic Nucleus

(2010) M. L. H. J. Hermes et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

A Possible Role for the Striatum in the Pathogenesis of the Cognitive Symptoms of Schizophrenia

(2010) Eleanor H. Simpson et al.   NEURON

Evidence for Abnormal Forward Trafficking of AMPA Receptors in Frontal Cortex of Elderly Patients with Schizophrenia

(2010) John C Hammond et al.   NEUROPSYCHOPHARMACOLOGY

Ras and Rap Signaling in Synaptic Plasticity and Mental Disorders

(2010) Ruth L. Stornetta et al.   NEUROSCIENTIST

The mGluR2/3 agonist LY379268 reverses post-weaning social isolation-induced recognition memory deficits in the rat

(2010) Caitlin A. Jones et al.   PSYCHOPHARMACOLOGY

Effects of a metabotropic glutamate receptor group II agonist LY354740 in animal models of positive schizophrenia symptoms and cognition

(2009) Chantal Schlumberger et al.   BEHAVIOURAL PHARMACOLOGY

Positive allosteric modulators of the metabotropic glutamate receptor 2 for the treatment of schizophrenia

(2009) Mark E Fraley   EXPERT OPINION ON THERAPEUTIC PATENTS

Activation of Glycogen Synthase Kinase-3  Is Required for Hyperdopamine and D2 Receptor-Mediated Inhibition of Synaptic NMDA Receptor Function in the Rat Prefrontal Cortex

(2009) Y.-C. Li et al.   JOURNAL OF NEUROSCIENCE

Synaptic AMPA Receptor Plasticity and Behavior

(2009) Helmut W. Kessels et al.   NEURON

The Dopamine Hypothesis of Schizophrenia: Version III--The Final Common Pathway

(2009) O. D. Howes et al.   SCHIZOPHRENIA BULLETIN

The effect of mGluR2 activation on signal transduction pathways and neuronal cell survival

(2008) Hyoung-gon Lee et al.   BRAIN RESEARCH

Evidence for the Role of Metabotropic Glutamate (mGlu)2 Not mGlu3 Receptors in the Preclinical Antipsychotic Pharmacology of the mGlu2/3 Receptor Agonist (-)-(1R,4S,5S,6S)-4-Amino-2-sulfonylbicyclo[3.1.0]hexane-4,6-dicarboxylic Acid (LY404039)

(2008) M. J. Fell et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Review: The group II metabotropic glutamate receptor 3 (mGluR3, mGlu3, GRM3): expression, function and involvement in schizophrenia

(2008) PJ Harrison et al.   JOURNAL OF PSYCHOPHARMACOLOGY

Schizophrenia: Moving Beyond Monoamine Antagonists

(2008) P. J. Conn et al.   MOLECULAR INTERVENTIONS

Formation of accumbens GluR2-lacking AMPA receptors mediates incubation of cocaine craving

(2008) Kelly L. Conrad et al.   NATURE

Allosteric modulators of GPCRs: a novel approach for the treatment of CNS disorders

(2008) P. Jeffrey Conn et al.   NATURE REVIEWS DRUG DISCOVERY

The role of NMDA receptors in regulating group II metabotropic glutamate receptor-mediated long-term depression in rat medial prefrontal cortex

(2008) Chiung-Chun Huang et al.   NEUROPHARMACOLOGY

Promise of mGluR2/3 activators in psychiatry

(2008) P Jeffrey Conn et al.   NEUROPSYCHOPHARMACOLOGY

Activation of metabotropic glutamate receptors as a novel approach for the treatment of schizophrenia

(2008) P. Jeffrey Conn et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

The possible involvement of metabotropic glutamate receptors in schizophrenia

(2007) Amir Krivoy et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY