Interleukin-1β Regulates Fat-Liver Crosstalk in Obesity by Auto-Paracrine Modulation of Adipose Tissue Inflammation and Expandability

The Inflammasome Puts Obesity in the Danger Zone

(2012) Rinke Stienstra et al.   Cell Metabolism

Lack of Interleukin-1 Receptor I (IL-1RI) Protects Mice From High-Fat Diet-Induced Adipose Tissue Inflammation Coincident With Improved Glucose Homeostasis

(2011) F. C. McGillicuddy et al.   DIABETES

Pathology of the liver in obese and diabetic ob/ob and db/db mice fed a standard or high-calorie diet

(2011) Viviane Trak-Smayra et al.   INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY

Increased AdipocyteS-Nitrosylation Targets Anti-lipolytic Action of Insulin

(2011) Hilla Ovadia et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Lack of interleukin-1α or interleukin-1β inhibits transformation of steatosis to steatohepatitis and liver fibrosis in hypercholesterolemic mice

(2011) Yehuda Kamari et al.   JOURNAL OF HEPATOLOGY

Microenvironment-Derived IL-1 and IL-17 Interact in the Control of Lung Metastasis

(2011) Y. Carmi et al.   JOURNAL OF IMMUNOLOGY

IL-1  and IL-1  Recruit Different Myeloid Cells and Promote Different Stages of Sterile Inflammation

(2011) P. Rider et al.   JOURNAL OF IMMUNOLOGY

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(2011) Alexander Moschen et al.   MOLECULAR MEDICINE

Fatty acid–induced NLRP3-ASC inflammasome activation interferes with insulin signaling

(2011) Haitao Wen et al.   NATURE IMMUNOLOGY

The NLRP3 inflammasome instigates obesity-induced inflammation and insulin resistance

(2011) Bolormaa Vandanmagsar et al.   NATURE MEDICINE

Inflammasome is a central player in the induction of obesity and insulin resistance

(2011) R. Stienstra et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Inflammasome-Mediated Caspase-1 Activation Controls Adipocyte Differentiation and Insulin Sensitivity

(2010) Rinke Stienstra et al.   Cell Metabolism

Dynamic, M2-Like Remodeling Phenotypes of CD11c+ Adipose Tissue Macrophages During High-Fat Diet-Induced Obesity in Mice

(2010) M. E. Shaul et al.   DIABETES

The Portal Theory Supported by Venous Drainage-Selective Fat Transplantation

(2010) J. M. Rytka et al.   DIABETES

Interleukin-1β May Mediate Insulin Resistance in Liver-Derived Cells in Response to Adipocyte Inflammation

(2010) Ori Nov et al.   ENDOCRINOLOGY

Weight loss and lipolysis promote a dynamic immune response in murine adipose tissue

(2010) Aliki Kosteli et al.   JOURNAL OF CLINICAL INVESTIGATION

NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals

(2010) Peter Duewell et al.   NATURE

Deletion of Fas in adipocytes relieves adipose tissue inflammation and hepatic manifestations of obesity in mice

(2009) Stephan Wueest et al.   JOURNAL OF CLINICAL INVESTIGATION

Interleukin-1beta and tumour necrosis factor-alpha impede neutral lipid turnover in macrophage-derived foam cells

(2008) Jenny Persson et al.   BMC IMMUNOLOGY

Neutrophils transiently infiltrate intra-abdominal fat early in the course of high-fat feeding

(2008) Vered Elgazar-Carmon et al.   JOURNAL OF LIPID RESEARCH

Adipocyte dysfunctions linking obesity to insulin resistance and type 2 diabetes

(2008) Adilson Guilherme et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

In vitro evolution of an antibody fragment population to find high-affinity hapten binders

(2008) H. Persson et al.   PROTEIN ENGINEERING DESIGN & SELECTION

A Stress Signaling Pathway in Adipose Tissue Regulates Hepatic Insulin Resistance

(2008) G. Sabio et al.   SCIENCE