Disturbed Subjective Sleep in Chinese Females with Type 2 Diabetes on Insulin Therapy

Objective:The aim of this study is to investigate the prevalence and determine the possible risk factors of poor sleep quality in Chinese type 2 diabetes patients with insulin treatment. Methods: 140 type 2 diabetes patients with insulin treatments were enrolled in our study. General characteristics and laboratory testing such glycosylated hemoglobin A1c (HbA1c), fasting plasma glucose (FPG), post-prandial plasma glucose (PPG) were measured. Every patient completed Chinese version of Pittsburgh Sleep Quality Index (PSQI) questionnaire. PSQI global score>5 was defined as poor sleep quality. Results: Global PSQI score was significantly higher in female type 2 diabetes patients with insulin treatment than male (7.52 vs 6.08, P<0.05). After adjusting for age, BMI, FPG, PPG, HbA1c and duration of diabetes, female is still an independent risk factor for poor sleep quality [OR = 2.55, 95% confidence interval (CI) = 1.24-5.27, P = 0.01]. Conclusion: The results suggest that we found poor sleep quality in female Chinese type 2 diabetes patients with insulin treatment and these findings may contribute to sleep disorder control in female type 2 diabetes.