GMP-Compliant, Large-Scale Expanded Allogeneic Natural Killer Cells Have Potent Cytolytic Activity against Cancer Cells In Vitro and In Vivo

Large-scale ex vivo expansion and characterization of natural killer cells for clinical applications

(2012) Natalia Lapteva et al.   CYTOTHERAPY

Clinical Cancer Therapy by NK Cells via Antibody-Dependent Cell-Mediated Cytotoxicity

(2011) Kory L. Alderson et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Helper Activity of Natural Killer Cells During the Dendritic Cell-mediated Induction of Melanoma-specific Cytotoxic T Cells

(2011) Jeffrey L. Wong et al.   JOURNAL OF IMMUNOTHERAPY

Clinical-Grade Generation of Active NK Cells from Cord Blood Hematopoietic Progenitor Cells for Immunotherapy Using a Closed-System Culture Process

(2011) Jan Spanholtz et al.   PLoS One

Rituximab (Rituxan)

(2010) D.T. Selewski et al.   AMERICAN JOURNAL OF NEURORADIOLOGY

Good manufacturing practice-compliant cell sorting and large-scale expansion of single KIR-positive alloreactive human natural killer cells for multiple infusions to leukemia patients

(2010) Uwe Siegler et al.   CYTOTHERAPY

Clinical-grade, large-scale, feeder-free expansion of highly active human natural killer cells for adoptive immunotherapy using an automated bioreactor

(2010) Tolga Sutlu et al.   CYTOTHERAPY

Intravital Imaging Reveals Distinct Dynamics for Natural Killer and CD8+ T Cells during Tumor Regression

(2010) Jacques Deguine et al.   IMMUNITY

Clinical-grade ex vivo-expanded human natural killer cells up-regulate activating receptors and death receptor ligands and have enhanced cytolytic activity against tumor cells

(2009) Maria Berg et al.   CYTOTHERAPY

Natural killer cell-based immunotherapy in cancer: current insights and future prospects

(2009) T. Sutlu et al.   JOURNAL OF INTERNAL MEDICINE

Infusion of the allogeneic cell line NK-92 in patients with advanced renal cell cancer or melanoma: a phase I trial

(2008) S. Arai et al.   CYTOTHERAPY

Human NK cells: from HLA class I-specific killer Ig-like receptors to the therapy of acute leukemias

(2008) Alessandro Moretta et al.   IMMUNOLOGICAL REVIEWS

Natural killer cell–directed therapies: moving from unexpected results to successful strategies

(2008) Magali Terme et al.   NATURE IMMUNOLOGY