Does Changing Androgen Receptor Status during Prostate Cancer Development Impact upon Cholesterol Homeostasis?

A key regulator of cholesterol homoeostasis, SREBP-2, can be targeted in prostate cancer cells with natural products

(2012) James R. Krycer et al.   BIOCHEMICAL JOURNAL

Akt acutely activates the cholesterogenic transcription factor SREBP-2

(2011) Winnie Luu et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Cross-talk between the Androgen Receptor and the Liver X Receptor

(2011) James Robert Krycer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Combined androgen blockade for prostate cancer: Review of efficacy, safety and cost-effectiveness

(2010) Hideyuki Akaza   CANCER SCIENCE

An update on androgen deprivation therapy for prostate cancer

(2010) Nima Sharifi et al.   ENDOCRINE-RELATED CANCER

Cholesterol as a Potential Target for Castration-Resistant Prostate Cancer

(2010) Alexis L. Twiddy et al.   PHARMACEUTICAL RESEARCH

Prolonged treatment with bicalutamide induces androgen receptor overexpression and androgen hypersensitivity

(2010) Hiromitsu Kawata et al.   PROSTATE

Correlation between circulatory, local prostatic, and intra-prostatic androgen levels

(2010) Mats Olsson et al.   PROSTATE

The Akt–SREBP nexus: cell signaling meets lipid metabolism

(2010) James R. Krycer et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Hypoxia drives prostate tumour progression and impairs the effectiveness of therapy, but can also promote cell death and serve as a therapeutic target

(2009) Stina Häggström Rudolfsson et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Special relationship between sterols and oxygen: Were sterols an adaptation to aerobic life?

(2009) Anne M. Galea et al.   FREE RADICAL BIOLOGY AND MEDICINE

Cholesterol Homeostasis in Two Commonly Used Human Prostate Cancer Cell-Lines, LNCaP and PC-3

(2009) James Robert Krycer et al.   PLoS One

Tissue culture media supplemented with 10% fetal calf serum contains a castrate level of testosterone

(2009) J.P. Michiel Sedelaar et al.   PROSTATE

Do the cholesterol-lowering properties of statins affect cancer risk?

(2008) Keith R. Solomon et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Expression of androgen receptor through androgen-converting enzymes is associated with biological aggressiveness in prostate cancer

(2007) K Wako et al.   JOURNAL OF CLINICAL PATHOLOGY