Randomized Phase I: Safety, Immunogenicity and Mucosal Antiviral Activity in Young Healthy Women Vaccinated with HIV-1 Gp41 P1 Peptide on Virosomes

Cervicovaginal HIV-1-neutralizing immunoglobulin A detected among HIV-1-exposed seronegative female partners in HIV-1-discordant couples

(2012) Robert Y. Choi et al.   AIDS

Antiviral Antibodies and T Cells Are Present in the Foreskin of Simian Immunodeficiency Virus-Infected Rhesus Macaques

(2012) K. Rothaeusler et al.   JOURNAL OF VIROLOGY

Broad and potent neutralization of HIV-1 by a gp41-specific human antibody

(2012) Jinghe Huang et al.   NATURE

Immune-Correlates Analysis of an HIV-1 Vaccine Efficacy Trial

(2012) Barton F. Haynes et al.   NEW ENGLAND JOURNAL OF MEDICINE

Protection against High-Dose Highly Pathogenic Mucosal SIV Challenge at Very Low Serum Neutralizing Titers of the Antibody-Like Molecule CD4-IgG2

(2012) Pascal Poignard et al.   PLoS One

Structure-guided Alterations of the gp41-directed HIV-1 Broadly Neutralizing Antibody 2F5 Reveal New Properties Regarding its Neutralizing Function

(2012) Javier Guenaga et al.   PLoS Pathogens

HIV-Specific Antibodies Capable of ADCC Are Common in Breastmilk and Are Associated with Reduced Risk of Transmission in Women with High Viral Loads

(2012) Jennifer Mabuka et al.   PLoS Pathogens

HIV Infection and Immune Defense of the Penis

(2011) Deborah Anderson et al.   AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY

Immunoglobulin Responses at the Mucosal Interface

(2011) Andrea Cerutti et al.   Annual Review of Immunology

Influenza virosomes as a vaccine adjuvant and carrier system

(2011) Christian Moser et al.   Expert Review of Vaccines

Immunization with HIV-1 gp41 Subunit Virosomes Induces Mucosal Antibodies Protecting Nonhuman Primates against Vaginal SHIV Challenges

(2011) Morgane Bomsel et al.   IMMUNITY

Innate and acquired immunity in the human penile urethra

(2011) Jeffrey Pudney et al.   JOURNAL OF REPRODUCTIVE IMMUNOLOGY

The human immunoglobulin A Fc receptor FcαRI: a multifaceted regulator of mucosal immunity

(2011) J E Bakema et al.   Mucosal Immunology

Phase I Randomised Clinical Trial of an HIV-1CN54, Clade C, Trimeric Envelope Vaccine Candidate Delivered Vaginally

(2011) David J. Lewis et al.   PLoS One

New insights in mucosal vaccine development

(2011) Vincent Pavot et al.   VACCINE

Decreased Fc receptor expression on innate immune cells is associated with impaired antibody-mediated cellular phagocytic activity in chronically HIV-1 infected individuals

(2011) Anne-Sophie Dugast et al.   VIROLOGY

The Role of Antibodies in HIV Vaccines

(2010) John R. Mascola et al.   Annual Review of Immunology

The good and evil of complement activation in HIV-1 infection

(2010) Qigui Yu et al.   Cellular & Molecular Immunology

Correlates of Protection Induced by Vaccination

(2010) S. A. Plotkin   Clinical and Vaccine Immunology

Vaccination Strategies to Promote Mucosal Antibody Responses

(2010) Kang Chen et al.   IMMUNITY

Lessons Drawn From Recent HIV Vaccine Efficacy Trials

(2010) Jonathan D Fuchs et al.   JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES

Structure and function of immunoglobulins

(2010) Harry W. Schroeder et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

A robust, high-throughput assay to determine the phagocytic activity of clinical antibody samples

(2010) Margaret E. Ackerman et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Antibody-mediated protection and the mucosal immune system of the genital tract: relevance to vaccine design

(2010) Jiri Mestecky et al.   JOURNAL OF REPRODUCTIVE IMMUNOLOGY

Targeting early infection to prevent HIV-1 mucosal transmission

(2010) Ashley T. Haase   NATURE

Setting of Methods for Analysis of Mucosal Antibodies in Seminal and Vaginal Fluids of HIV Seropositive Subjects from Cambodian and Italian Cohorts

(2010) Carla Donadoni et al.   PLoS One

Targeting Trojan Horse leukocytes for HIV prevention

(2009) Deborah J Anderson et al.   AIDS

Broadly Neutralizing Monoclonal Antibodies 2F5 and 4E10 Directed against the Human Immunodeficiency Virus Type 1 gp41 Membrane-Proximal External Region Protect against Mucosal Challenge by Simian-Human Immunodeficiency Virus SHIVBa-L

(2009) A. J. Hessell et al.   JOURNAL OF VIROLOGY

HIV-1 gp41-specific monoclonal mucosal IgAs derived from highly exposed but IgG-seronegative individuals block HIV-1 epithelial transcytosis and neutralize CD4+ cell infection: an IgA gene and functional analysis

(2009) D Tudor et al.   Mucosal Immunology

Vaccination with ALVAC and AIDSVAX to Prevent HIV-1 Infection in Thailand

(2009) Supachai Rerks-Ngarm et al.   NEW ENGLAND JOURNAL OF MEDICINE

Eleven years of Inflexal® V—a virosomal adjuvanted influenza vaccine

(2009) Christian Herzog et al.   VACCINE

Broadly Neutralizing Human Anti-HIV Antibody 2G12 Is Effective in Protection against Mucosal SHIV Challenge Even at Low Serum Neutralizing Titers

(2009) Ann J. Hessell et al.   PLoS Pathogens

The ‘immunologic advantage’ of HIV-exposed seronegative individuals

(2008) Masaaki Miyazawa et al.   AIDS

Cervical HIV-Specific IgA in a Population of Commercial Sex Workers Correlates with Repeated Exposure But Not Resistance to HIV

(2008) Rachel E. Horton et al.   AIDS RESEARCH AND HUMAN RETROVIRUSES

Sensitivity by combination: immuno-PCR and related technologies

(2008) Michael Adler et al.   ANALYST

Contribution of influenza immunity and virosomal-formulated synthetic peptide to cellular immune responses in a phase I subunit malaria vaccine trial

(2008) Elisabetta Peduzzi et al.   CLINICAL IMMUNOLOGY

Both lipid environment and pH are critical for determining physiological solution structure of 3-D-conserved epitopes of the HIV-1 gp41-MPER peptide P1

(2008) Jérôme Coutant et al.   FASEB JOURNAL

Influenza vaccines: The virosome concept

(2008) Jan Wilschut   IMMUNOLOGY LETTERS

The failed HIV Merck vaccine study: a step back or a launching point for future vaccine development?

(2008) Rafick-Pierre Sekaly   JOURNAL OF EXPERIMENTAL MEDICINE

A Bispecific Antibody Composed of a Nonneutralizing Antibody to the gp41 Immunodominant Region and an Anti-CD89 Antibody Directs Broad Human Immunodeficiency Virus Destruction by Neutrophils

(2008) M. Duval et al.   JOURNAL OF VIROLOGY

The Membrane-Proximal External Region of the Human Immunodeficiency Virus Type 1 Envelope: Dominant Site of Antibody Neutralization and Target for Vaccine Design

(2008) M. Montero et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

Differential immunogenicity of vaccinia and HIV-1 components of a human recombinant vaccine in mucosal and blood compartments

(2008) Peter A. Anton et al.   VACCINE

Phase I study of a candidate vaccine based on recombinant HIV-1 gp160 (MN/LAI) administered by the mucosal route to HIV-seronegative volunteers: The ANRS VAC14 study

(2007) Gilles Pialoux et al.   VACCINE