Vitamin E δ-Tocotrienol Induces p27Kip1-Dependent Cell-Cycle Arrest in Pancreatic Cancer Cells via an E2F-1-Dependent Mechanism

Abstract 1299: A phase I dose-escalation study of the safety, PK, and PD of vitamin E Δ-tocotrienol administered to subjects with resectable pancreatic exocrine neoplasia

(2012) Gregory M. Springett et al.   CANCER RESEARCH

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Vitamin E  -Tocotrienol Augments the Antitumor Activity of Gemcitabine and Suppresses Constitutive NF- B Activation in Pancreatic Cancer

(2011) K. Husain et al.   MOLECULAR CANCER THERAPEUTICS

Honokiol Arrests Cell Cycle, Induces Apoptosis, and Potentiates the Cytotoxic Effect of Gemcitabine in Human Pancreatic Cancer Cells

(2011) Sumit Arora et al.   PLoS One

Cancer Statistics, 2010

(2010) A. Jemal et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Gefitinib Inhibits the Proliferation of Pancreatic Cancer Cells via Cell Cycle Arrest

(2009) Xiaohua Zhou et al.   Anatomical Record-Advances in Integrative Anatomy and Evolutionary Biology

Inhibition of proliferation and induction of apoptosis by γ-tocotrienol in human colon carcinoma HT-29 cells

(2009) Wei-Li Xu et al.   NUTRITION

d-δ-Tocotrienol-Mediated Suppression of the Proliferation of Human PANC-1, MIA PaCa-2, and BxPC-3 Pancreatic Carcinoma Cells

(2009) Deema Hussein et al.   PANCREAS

Vitamin E δ-Tocotrienol Levels in Tumor and Pancreatic Tissue of Mice after Oral Administration

(2009) Kazim Husain et al.   PHARMACOLOGY

mTOR-Raptor Binds and Activates SGK1 to Regulate p27 Phosphorylation

(2008) Feng Hong et al.   MOLECULAR CELL