Endoglin Haploinsufficiency Promotes Fibroblast Accumulation during Wound Healing through Akt Activation

β-catenin signaling

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Loss of Akt activity increases circulating soluble endoglin release in preeclampsia: identification of inter-dependency between Akt-1 and heme oxygenase-1

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Endoglin promotes TGF-β/Smad1 signaling in scleroderma fibroblasts

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Transforming Growth Factor-? and Endoglin Signaling Orchestrate Wound Healing

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Tranilast inhibits cell proliferation and migration and promotes apoptosis in murine breast cancer

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Endoglin negatively regulates transforming growth factor β1-induced profibrotic responses in intestinal fibroblasts

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Expression and functional analysis of endoglin in isolated liver cells and its involvement in fibrogenic Smad signalling

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Mechanism of the inhibitory effect of atorvastatin on endoglin expression induced by transforming growth factor-β1 in cultured cardiac fibroblasts

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Role of extracellular signal-regulated kinase and AKT cascades in regulating hypoxia-induced angiogenic factors produced by a trophoblast-derived cell line

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Organ-specific lymphangiectasia, arrested lymphatic sprouting, and maturation defects resulting from gene-targeting of the PI3K regulatory isoforms p85α, p55α, and p50α

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Endoglin haploinsufficiency reduces radiation-induced fibrosis and telangiectasia formation in mouse kidneys

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Endoglin in angiogenesis and vascular diseases

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Mechanisms of Fibrogenesis

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L- and S-endoglin differentially modulate TGF 1 signaling mediated by ALK1 and ALK5 in L6E9 myoblasts

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Control of thrombin signaling through PI3K is a mechanism underlying plasticity between hair follicle dermal sheath and papilla cells

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GSK-3β in mouse fibroblasts controls wound healing and fibrosis through an endothelin-1–dependent mechanism

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Wound repair and regeneration

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