The Developmental Regulator Pax6 Is Essential for Maintenance of Islet Cell Function in the Adult Mouse Pancreas

Pax6 Is Crucial for β-Cell Function, Insulin Biosynthesis, and Glucose-Induced Insulin Secretion

(2012) Yvan Gosmain et al.   MOLECULAR ENDOCRINOLOGY

Sox2+ Adult Stem and Progenitor Cells Are Important for Tissue Regeneration and Survival of Mice

(2011) Katrin Arnold et al.   Cell Stem Cell

Pancreas organogenesis: From bud to plexus to gland

(2011) Fong Cheng Pan et al.   DEVELOPMENTAL DYNAMICS

A common variant upstream of the PAX6 gene influences islet function in man

(2011) E. Ahlqvist et al.   DIABETOLOGIA

Discovery and assessment of conserved Pax6 target genes and enhancers

(2011) Pedro Coutinho et al.   GENOME RESEARCH

Relative roles of the different Pax6 domains for pancreatic alpha cell development

(2010) Petra Dames et al.   BMC DEVELOPMENTAL BIOLOGY

Pax6 Controls the Expression of Critical Genes Involved in Pancreatic α Cell Differentiation and Function

(2010) Yvan Gosmain et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Emerging properties of animal gene regulatory networks

(2010) Eric H. Davidson   NATURE

Mice With Hyperghrelinemia Are Hyperphagic and Glucose Intolerant and Have Reduced Leptin Sensitivity

(2009) G. A. Bewick et al.   DIABETES

Kinetics of Blood Glucose in Mice Carrying Hemizygous Pax6

(2009) Yumiko NITTA et al.   EXPERIMENTAL ANIMALS

Pax6 Regulates the Proglucagon Processing Enzyme PC2 and Its Chaperone 7B2

(2009) L. S. Katz et al.   MOLECULAR AND CELLULAR BIOLOGY

Normal ventral telencephalic expression of Pax6 is required for normal development of thalamocortical axons in embryonic mice

(2009) T Ian Simpson et al.   Neural Development

Expression of zebrafish pax6b in pancreas is regulated by two enhancers containing highly conserved cis-elements bound by PDX1, PBX and PREP factors

(2008) François M Delporte et al.   BMC DEVELOPMENTAL BIOLOGY

Paired box 6 (PAX6) regulates glucose metabolism via proinsulin processing mediated by prohormone convertase 1/3 (PC1/3)

(2008) J. H. Wen et al.   DIABETOLOGIA

Pax6Haploinsufficiency Causes Abnormal Metabolic Homeostasis by Down-Regulating Glucagon-Like Peptide 1 in Mice

(2008) Jun Ding et al.   ENDOCRINOLOGY

Genes controlling pancreas ontogeny

(2008) Claire Bonal et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY

A Dlx2- and Pax6-Dependent Transcriptional Code for Periglomerular Neuron Specification in the Adult Olfactory Bulb

(2008) M. S. Brill et al.   JOURNAL OF NEUROSCIENCE

Subfunctionalization of Duplicated Zebrafish pax6 Genes by cis-Regulatory Divergence

(2008) Dirk A. Kleinjan et al.   PLoS Genetics

Concise Review: Pax6 Transcription Factor Contributes to both Embryonic and Adult Neurogenesis as a Multifunctional Regulator

(2008) Noriko Osumi et al.   STEM CELLS

Characterization of Adult Ghrelin and Ghrelin Receptor Knockout Mice under Positive and Negative Energy Balance

(2007) Yuxiang Sun et al.   ENDOCRINOLOGY