Time-Dependent Stabilization of Hypoxia Inducible Factor-1α by Different Intracellular Sources of Reactive Oxygen Species

Bevacizumab in metastatic colorectal cancer and carcino-embryonic antigen kinetics

(2011) Diocésio Pinto de Andrade et al.   ANTI-CANCER DRUGS

EMT and Oxidative Stress: A Bidirectional Interplay Affecting Tumor Malignancy

(2011) Elisa Giannoni et al.   ANTIOXIDANTS & REDOX SIGNALING

HIF Induces Human Embryonic Stem Cell Markers in Cancer Cells

(2011) J. Mathieu et al.   CANCER RESEARCH

Src activates HIF-1α not through direct phosphorylation of HIF-1α-specific prolyl-4 hydroxylase 2 but through activation of the NADPH oxidase/Rac pathway

(2011) Ho-Youl Lee et al.   CARCINOGENESIS

Interruption of mitochondrial complex IV activity and cytochrome c expression activated O2∙−-mediated cell survival in silibinin-treated human melanoma A375-S2 cells via IGF-1R–PI3K–Akt and IGF-1R–PLC γ–PKC pathways

(2011) Yuan-yuan Jiang et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

HIF-1α stabilization by mitochondrial ROS promotes Met-dependent invasive growth and vasculogenic mimicry in melanoma cells

(2011) Giuseppina Comito et al.   FREE RADICAL BIOLOGY AND MEDICINE

A vascular niche and a VEGF–Nrp1 loop regulate the initiation and stemness of skin tumours

(2011) Benjamin Beck et al.   NATURE

NADPH Oxidase Subunit 4-Mediated Reactive Oxygen Species Contribute to Cycling Hypoxia-Promoted Tumor Progression in Glioblastoma Multiforme

(2011) Chia-Hung Hsieh et al.   PLoS One

From Chemotherapy to Targeted Therapy in Adjuvant Treatment for Stage III Colon Cancer

(2011) Aimery de Gramont et al.   SEMINARS IN ONCOLOGY

Metastasis: cancer cell’s escape from oxidative stress

(2010) Giovambattista Pani et al.   CANCER AND METASTASIS REVIEWS

Cell Responses to Oxidative Stressors

(2010) Amelia Cataldi   CURRENT PHARMACEUTICAL DESIGN

Constitutive HIF-1 activity in malignant melanoma

(2010) Silke Kuphal et al.   EUROPEAN JOURNAL OF CANCER

Hypoxia-inducible Factor-1 Activation in Nonhypoxic Conditions: The Essential Role of Mitochondrial-derived Reactive Oxygen Species

(2010) David A. Patten et al.   MOLECULAR BIOLOGY OF THE CELL

NADPH oxidase-mediated reactive oxygen species production activates hypoxia-inducible factor-1 (HIF-1) via the ERK pathway after hyperthermia treatment

(2010) E. J. Moon et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mitochondrial Regulation of Cell Survival and Death During Low-Oxygen Conditions

(2009) Colleen M. Snyder et al.   ANTIOXIDANTS & REDOX SIGNALING

Oxygen Sensors at the Crossroad of Metabolism

(2009) Julián Aragonés et al.   Cell Metabolism

Regulation of Oxygen Homeostasis by Hypoxia-Inducible Factor 1

(2009) Gregg L. Semenza   PHYSIOLOGY

LPS Induces Hypoxia-Inducible Factor 1 Activation in Macrophage-Differentiated Cells in a Reactive Oxygen Species–Dependent Manner

(2008) Kenichiro Nishi et al.   ANTIOXIDANTS & REDOX SIGNALING

Redox Regulation of Cell Survival

(2008) Dunyaporn Trachootham et al.   ANTIOXIDANTS & REDOX SIGNALING

Differential Involvement of Vascular Endothelial Growth Factor in the Survival of Hypoxic Colon Cancer Cells

(2008) M. Calvani et al.   CANCER RESEARCH

Mitochondrial complex III regulates hypoxic activation of HIF

(2008) T Klimova et al.   CELL DEATH AND DIFFERENTIATION