Article
Genetics & Heredity
Robert J. Pignolo, Genevieve Baujat, Matthew A. Brown, Carmen De Cunto, Edward C. Hsiao, Richard Keen, Mona Al Mukaddam, Kim-Hanh Le Quan Sang, Amy Wilson, Rose Marino, Andrew Strahs, Frederick S. Kaplan
Summary: This study presents the first prospective, international, natural history study of fibrodysplasia ossificans progressiva (FOP), a rare genetic disorder. The results demonstrate the debilitating effects and progressive nature of FOP, with the most significant progression observed during childhood and early adulthood.
GENETICS IN MEDICINE
(2022)
Review
Behavioral Sciences
Beatrice Arosio, Franca Rosa Guerini, Richard C. Oude Voshaar, Ivan Aprahamian
Summary: This article summarizes the neurotrophin hypothesis of depression and the relationship between blood BDNF concentration and MDD. Existing research suggests that changes in BDNF levels are associated with clinical manifestations of depression, but cannot yet be used as a biomarker in clinical practice.
FRONTIERS IN BEHAVIORAL NEUROSCIENCE
(2021)
Article
Endocrinology & Metabolism
Nicola Tempest, Madeleine Boyers, Alice Carter, Steven Lane, Dharani K. Hapangama
Summary: This study found an association between symptoms relevant to restless leg syndrome and endometriosis, showing that women with a reported prior surgical diagnosis or symptoms suggestive of endometriosis have a significantly higher prevalence of a prior formal diagnosis or symptoms suggestive of restless leg syndrome.
FRONTIERS IN ENDOCRINOLOGY
(2021)
Article
Clinical Neurology
Waka Nogami, Atsuo Nakagawa, Nariko Katayama, Yuka Kudo, Mizuki Amano, Sakae Ihara, Chika Kurata, Yuki Kobayashi, Yohei Sasaki, Natsum Ishikawa, Yasunori Sato, Masaru Mimura
Summary: The present study aimed to evaluate the relationship between personality traits and sustained remission (SR) among patients with major depression. The results showed that patients with lower levels of personal reserve were more likely to achieve SR. In addition, the SR group had milder depression symptoms at baseline.
NEUROPSYCHIATRIC DISEASE AND TREATMENT
(2022)
Article
Nutrition & Dietetics
Fanny Petermann-Rocha, Carlos Celis-Morales, Jill P. Pell, Frederick K. Ho
Summary: This study compares the cardiovascular risk among vegetarian diets that meet health guidelines, those that do not, and diets that include red meat. The results show that both healthier vegetarians and meat-eaters have a lower risk of cardiovascular disease compared to less healthy meat-eaters. This suggests that future research should consider the overall dietary patterns of vegetarians, rather than solely focusing on meat consumption.
CLINICAL NUTRITION
(2023)
Article
Clinical Neurology
Solene Charriere, Jean-Yves Maigne, Emmanuel Couzi, Marie-Martine Lefevre-Colau, Francois Rannou, Christelle Nguyen
Summary: In adults with chronic coccydynia receiving conservative treatment, symptoms decrease over time, but significantly persist at 36 months in more than half of them. For patients with posterior coccyx dislocation, coccygectomy may be considered rapidly.
EUROPEAN SPINE JOURNAL
(2021)
Article
Clinical Neurology
Phoenix K. H. Mo, Huahua Hu, Mary Ip, Willa Dong, Joseph T. F. Lau, Zixin Wang
Summary: The study found a significant positive relationship between stress, avoidant coping, and depression among Chinese MSM. Age played a moderating role in this relationship, with younger MSM showing a stronger impact of stress and avoidant coping on depression.
JOURNAL OF AFFECTIVE DISORDERS
(2021)
Article
Clinical Neurology
Jong-ha Lee, SuHyuk Chi, Minsoo Ko, Minjae Song, Byung-Joo Ham, Young-Hoon Ko, Sang-il Suh, Moon-Soo Lee
Summary: The study found that compared to healthy controls, patients with MDD had significantly increased FA values, but these values decreased after 3 months of treatment. This suggests that early pharmacological treatment may help restore brain integrity.
JOURNAL OF AFFECTIVE DISORDERS
(2021)
Article
Health Care Sciences & Services
Kara Suvada, Mohammed K. Ali, Lydia Chwastiak, Subramani Poongothai, Karl M. F. Emmert-Fees, Ranjit Mohan Anjana, Rajesh Sagar, Radha Shankar, Gumpeny R. Sridhar, Madhu Kasuri, Aravind R. Sosale, Bhavana Sosale, Deepa Rao, Nikhil Tandon, K. M. Venkat Narayan, Viswanathan Mohan, Shivani A. Patel
Summary: This study investigated the effects of collaborative care on patients with depression and diabetes over a period of 36 months. The results showed that there were no differences in improvements in multiple or single risk factors at 36 months between the collaborative care and usual care groups. However, patients who had achieved improvements in depressive symptoms and glucose levels at 12 months were more likely to maintain these improvements at 36 months.
JOURNAL OF GENERAL INTERNAL MEDICINE
(2023)
Article
Clinical Neurology
Bruno Paz Mosqueiro, Marco Antonio Caldieraro, Mateus Messinger, Felipe Bauer Pinto Costa, John R. Peteet, Marcelo P. Fleck
Summary: The study examined the impact of religiosity on suicide risk and symptom remission in severely depressed patients. Results indicated that religiosity played a significant role in reducing suicide risk and promoting recovery.
JOURNAL OF AFFECTIVE DISORDERS
(2021)
Article
Endocrinology & Metabolism
Yoshimi Ouchi, Katsuhiko Nakatsukasa, Koichi Sakaguchi, Midori Morita, Hiroshi Koyama, Takayuki Matsuda, Makoto Kato, Eiichi Konishi, Hisako Ono, Tetsuya Taguchi
Summary: This study showed that twice-yearly administration of denosumab to breast cancer patients treated with adjuvant AI resulted in significant increases in bone mineral density at the lumbar spine, right femoral neck, and left femoral neck over a 36-month treatment period. There were no non-traumatic clinical fractures in patients receiving AI and denosumab treatment.
JOURNAL OF BONE AND MINERAL METABOLISM
(2021)
Article
Immunology
Jae-Min Kim, Hee-Ju Kang, Ju-Wan Kim, Min Jhon, Wonsuk Choi, Ju-Yeon Lee, Sung-Wan Kim, Il-Seon Shin, Min-Gon Kim, Robert Stewart
Summary: This study investigated the association between serum biomarkers and treatment outcomes in depression. The findings suggest that certain serum biomarkers are prospectively associated with remission at 12-week and 12-month periods. Inflammatory markers, in particular, show good predictability for remission, but the association weakens with increasing treatment steps.
BRAIN BEHAVIOR AND IMMUNITY
(2022)
Article
Clinical Neurology
Olivier D. Steen, Claudia D. van Borkulo, Hanna M. van Loo
Summary: The study found differences in symptom endorsement among individuals with major depression based on different risk factors, but no robust differences were found in symptom networks across sex, familial risk, and adversity.
JOURNAL OF AFFECTIVE DISORDERS
(2021)
Article
Medicine, General & Internal
Xin Liu, Chunmei Cheng, Zhaojun Liu, Wenjun Fan, Chunhua Liu, Yin Liu
Summary: This study found that anxiety rates increased gradually while depression rates slightly rose without statistical significance in AIS patients during the 36-month follow-up. Female gender, diabetes, hypertension, NIHSS score, and education duration independently predicted the elevated risk of poststroke anxiety or depression in AIS patients.
Article
Medicine, General & Internal
Roger C. Ho, Anna N. Chua, Syeda Fabeha Husain, Wanqiu Tan, Fengyi Hao, Giang T. Vu, Bach X. Tran, Hien Thu Nguyen, Roger S. McIntyre, Cyrus S. Ho
Summary: This study aimed to compare bone mineral density and bone metabolism markers between medicated premenopausal women with major depressive disorder and healthy controls in Singapore. The results showed no significant differences in bone density and bone metabolism markers between the two groups.
