G-Protein Coupled Receptor 30 (GPR30): A Novel Regulator of Endothelial Inflammation

Minireview: G Protein-Coupled Estrogen Receptor-1, GPER-1: Its Mechanism of Action and Role in Female Reproductive Cancer, Renal and Vascular Physiology

(2012) Edward J. Filardo et al.   ENDOCRINOLOGY

Neuronal nitric oxide synthase regulates endothelial inflammation

(2012) Subhadeep Chakrabarti et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Estradiol Modulates Tumor Necrosis Factor-Induced Endothelial Inflammation: Role of Tumor Necrosis Factor Receptor 2

(2012) Subhadeep Chakrabarti et al.   JOURNAL OF VASCULAR RESEARCH

Improvement of Vascular Function by Acute and Chronic Treatment with the GPR30 Agonist G1 in Experimental Diabetes Mellitus

(2012) Zi-lin Li et al.   PLoS One

Position paper: The membrane estrogen receptor GPER – Clues and questions

(2012) Matthias Barton   STEROIDS

G protein-coupled oestrogen receptor 1 (GPER1)/GPR30: a new player in cardiovascular and metabolic oestrogenic signalling

(2011) Bengt-Olof Nilsson et al.   BRITISH JOURNAL OF PHARMACOLOGY

GPR30 Activation Opposes Estrogen-Dependent Uterine Growth via Inhibition of Stromal ERK1/2 and Estrogen Receptor Alpha (ERα) Phosphorylation Signals

(2011) Fei Gao et al.   ENDOCRINOLOGY

Equol-Stimulated Mitochondrial Reactive Oxygen Species Activate Endothelial Nitric Oxide Synthase and Redox Signaling in Endothelial Cells

(2011) David J. Rowlands et al.   HYPERTENSION

The GPER1 Agonist G-1 Attenuates Endothelial Cell Proliferation by Inhibiting DNA Synthesis and Accumulating Cells in the S and G2 Phases of the Cell Cycle

(2011) Anders Holm et al.   JOURNAL OF VASCULAR RESEARCH

Endothelium-dependent relaxation by G protein-coupled receptor 30 agonists in rat carotid arteries

(2010) Brad R. S. Broughton et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

GPR30, but not estrogen receptor-α, is crucial in the treatment of experimental autoimmune encephalomyelitis by oral ethinyl estradiol

(2010) Melissa A Yates et al.   BMC IMMUNOLOGY

Nuclear Alternate Estrogen Receptor GPR30 Mediates 17 -Estradiol-Induced Gene Expression and Migration in Breast Cancer-Associated Fibroblasts

(2010) A. Madeo et al.   CANCER RESEARCH

Estradiol and G1 Reduce Infarct Size and Improve Immunosuppression after Experimental Stroke

(2010) B. Zhang et al.   JOURNAL OF IMMUNOLOGY

Activation of G protein-coupled receptor 30 modulates hormone secretion and counteracts cytokine-induced apoptosis in pancreatic islets of female mice

(2010) Alexander Balhuizen et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Estrogen receptor-  promotes endothelial cell motility through focal adhesion kinase

(2010) A. M. Sanchez et al.   MOLECULAR HUMAN REPRODUCTION

Signaling via GPR30 protects the myocardium from ischemia/reperfusion injury

(2010) Brent R. Weil et al.   SURGERY

Estradiol-mediated ERK phosphorylation and apoptosis in vascular smooth muscle cells requires GPR 30

(2009) Qingming Ding et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

17 -Estradiol induces protein S-nitrosylation in the endothelium

(2009) S. Chakrabarti et al.   CARDIOVASCULAR RESEARCH

Beneficial role of the GPR30 agonist G-1 in an animal model of multiple sclerosis

(2009) Eric Blasko et al.   JOURNAL OF NEUROIMMUNOLOGY

High glucose-induced oxidative stress alters estrogen effects on ERα and ERβ in human endothelial cells: Reversal by AMPK activator

(2009) Subhadeep Chakrabarti et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Role of estrogen receptor subtypes in estrogen-induced organ-specific vasorelaxation after trauma-hemorrhage

(2008) Zheng F. Ba et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Sex steroids and vascular responses in hypertension and aging

(2008) Xiaoying Qiao et al.   Gender Medicine

Increased Lectin-Like Oxidized Low-Density Lipoprotein Receptor-1 Expression in the Maternal Vasculature of Women With Preeclampsia

(2008) Sowndramalingam Sankaralingam et al.   HYPERTENSION

Metformin inhibits TNF-α-induced IκB kinase phosphorylation, IκB-α degradation and IL-6 production in endothelial cells through PI3K-dependent AMPK phosphorylation

(2008) Nan-Lan Huang et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Inhibition of TNF-α reduces transplant arteriosclerosis in a murine aortic transplant model

(2008) Martina Wollin et al.   TRANSPLANT INTERNATIONAL

Estrogen decreases TNF-α and oxidized LDL induced apoptosis in endothelial cells

(2007) M. Florian et al.   STEROIDS