Genetic Variants in PNPLA3 and Risk of Non-Alcoholic Fatty Liver Disease in a Han Chinese Population

Two genetic variants in FABP1 and susceptibility to non-alcohol fatty liver disease in a Chinese population

(2012) Xian-E Peng et al.   GENE

Genetic variant inPNPLA3is associated with nonalcoholic fatty liver disease in China

(2011) Yiling Li et al.   HEPATOLOGY

Common polymorphism in the PNPLA3/adiponutrin gene confers higher risk of cirrhosis and liver damage in alcoholic liver disease

(2011) Eric Trépo et al.   JOURNAL OF HEPATOLOGY

Association of PNPLA3 with non-alcoholic fatty liver disease in a minority cohort: the Insulin Resistance Atherosclerosis Family Study

(2011) Lynne E. Wagenknecht et al.   LIVER INTERNATIONAL

The Association of PNPLA3 Variants with Liver Enzymes in Childhood Obesity Is Driven by the Interaction with Abdominal Fat

(2011) Emanuele Miraglia del Giudice et al.   PLoS One

Genome-Wide Association Analysis Identifies Variants Associated with Nonalcoholic Fatty Liver Disease That Have Distinct Effects on Metabolic Traits

(2011) Elizabeth K. Speliotes et al.   PLoS Genetics

Review article: epidemiology, pathogenesis and potential treatments of paediatric non-alcoholic fatty liver disease

(2010) N. J. BARSHOP et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Genome-Wide Association Study Identifies Variants Associated With Histologic Features of Nonalcoholic Fatty Liver Disease

(2010) Naga Chalasani et al.   GASTROENTEROLOGY

A common variant in the patatin-like phospholipase 3 gene (PNPLA3) is associated with fatty liver disease in obese children and adolescents

(2010) Nicola Santoro et al.   HEPATOLOGY

PNPLA3variants specifically confer increased risk for histologic nonalcoholic fatty liver disease but not metabolic disease

(2010) Elizabeth K. Speliotes et al.   HEPATOLOGY

The association of genetic variability in patatin-like phospholipase domain-containing protein 3 (PNPLA3) with histological severity of nonalcoholic fatty liver disease

(2010) Yaron Rotman et al.   HEPATOLOGY

The 148M allele of the PNPLA3 gene is associated with indices of liver damage early in life

(2010) Stefano Romeo et al.   JOURNAL OF HEPATOLOGY

A feed-forward loop amplifies nutritional regulation of PNPLA3

(2010) Yongcheng Huang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dissociation Between Fatty Liver and Insulin Resistance in Humans Carrying a Variant of the Patatin-Like Phospholipase 3 Gene

(2009) K. Kantartzis et al.   DIABETES

Heritability of Nonalcoholic Fatty Liver Disease

(2009) Jeffrey B. Schwimmer et al.   GASTROENTEROLOGY

Morbid obesity exposes the association between PNPLA3 I148M (rs738409) and indices of hepatic injury in individuals of European descent

(2009) S Romeo et al.   INTERNATIONAL JOURNAL OF OBESITY

A Sequence Variation (I148M) in PNPLA3 Associated with Nonalcoholic Fatty Liver Disease Disrupts Triglyceride Hydrolysis

(2009) Shaoqing He et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The expression level of non-alcoholic fatty liver disease-related gene PNPLA3 in hepatocytes is highly influenced by hepatic lipid status

(2009) Menno Hoekstra et al.   JOURNAL OF HEPATOLOGY

A nonsynonymous gene variant in the adiponutrin gene is associated with nonalcoholic fatty liver disease severity

(2009) Silvia Sookoian et al.   JOURNAL OF LIPID RESEARCH

Tri-iodothyronine upregulates adiponutrin mRNA expression in rat and human adipocytes

(2009) R.M. Calvo et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Population-Based Genome-wide Association Studies Reveal Six Loci Influencing Plasma Levels of Liver Enzymes

(2008) Xin Yuan et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Genetic variants in STAT3 are associated with nonalcoholic fatty liver disease

(2008) Silvia Sookoian et al.   CYTOKINE

Adipose triglyceride lipase regulates basal lipolysis and lipid droplet size in adipocytes

(2008) Hideaki Miyoshi et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Guidelines for the diagnosis and treatment of nonalcoholic fatty liver diseases

(2008) Min De ZENG et al.   Journal of Digestive Diseases

A Val227Ala substitution in the peroxisome proliferator activated receptor alpha (PPAR alpha) gene associated with non-alcoholic fatty liver disease and decreased waist circumference and waist-to-hip ratio

(2008) Shaohua Chen et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Polymorphisms of MRP2 (ABCC2) are associated with susceptibility to nonalcoholic fatty liver disease

(2008) Silvia Sookoian et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Genetic variation in PNPLA3 confers susceptibility to nonalcoholic fatty liver disease

(2008) Stefano Romeo et al.   NATURE GENETICS