Th22 Cells as Well as Th17 Cells Expand Differentially in Patients with Early-Stage and Late-Stage Myelodysplastic Syndrome

Increased intratumoral IL-22-producing CD4+ T cells and Th22 cells correlate with gastric cancer progression and predict poor patient survival

(2012) Yuan Zhuang et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Differentiation and Recruitment of IL-22–Producing Helper T Cells Stimulated by Pleural Mesothelial Cells in Tuberculous Pleurisy

(2011) Zhi-Jian Ye et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Role of immune responses in the pathogenesis of low-risk MDS and high-risk MDS: implications for immunotherapy

(2011) Shikhar Aggarwal et al.   BRITISH JOURNAL OF HAEMATOLOGY

Th17 and Foxp3+ T regulatory cell dynamics and distribution in myelodysplastic syndromes

(2011) Irene Bouchliou et al.   CLINICAL IMMUNOLOGY

Elevated Th22 Cells Correlated with Th17 Cells in Patients with Rheumatoid Arthritis

(2011) Lei Zhang et al.   JOURNAL OF CLINICAL IMMUNOLOGY

Interferon-  and tumor necrosis factor-  induce an immunoinhibitory molecule, B7-H1, via nuclear factor- B activation in blasts in myelodysplastic syndromes

(2010) A. Kondo et al.   BLOOD

Elevated IL-17 produced by TH17 cells promotes myeloma cell growth and inhibits immune function in multiple myeloma

(2010) R. H. Prabhala et al.   BLOOD

Reduced SMAD7 Leads to Overactivation of TGF-  Signaling in MDS that Can Be Reversed by a Specific Inhibitor of TGF-  Receptor I Kinase

(2010) L. Zhou et al.   CANCER RESEARCH

Interleukin-22 is a negative regulator of the allergic response

(2010) Bruno Schnyder et al.   CYTOKINE

Activation of the aryl hydrocarbon receptor reveals distinct requirements for IL-22 and IL-17 production by human T helper cells

(2010) Jean-Marie Ramirez et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Decreased plasma IL22 levels, but not increased IL17 and IL23 levels, correlate with disease activity in patients with systemic lupus erythematosus

(2009) F Cheng et al.   ANNALS OF THE RHEUMATIC DISEASES

IL-17 and Th17 Cells

(2009) Thomas Korn et al.   Annual Review of Immunology

The 2008 revision of the World Health Organization (WHO) classification of myeloid neoplasms and acute leukemia: rationale and important changes

(2009) J. W. Vardiman et al.   BLOOD

IL-17-producing CD4+T cells, pro-inflammatory cytokines and apoptosis are increased in low risk myelodysplastic syndrome

(2009) Shahram Y. Kordasti et al.   BRITISH JOURNAL OF HAEMATOLOGY

Patients with myelodysplastic syndromes display several T-cell expansions, which are mostly polyclonal in the CD4+ subset and oligoclonal in the CD8+ subset

(2009) Claudio Fozza et al.   EXPERIMENTAL HEMATOLOGY

Immune mediated autologous cytotoxicity against hematopoietic precursor cells in patients with myelodysplastic syndrome

(2009) M. E.D. Chamuleau et al.   HAEMATOLOGICA

IL-22 Produced by Human NK Cells Inhibits Growth of Mycobacterium tuberculosis by Enhancing Phagolysosomal Fusion

(2009) R. Dhiman et al.   JOURNAL OF IMMUNOLOGY

Identification of a human helper T cell population that has abundant production of interleukin 22 and is distinct from TH-17, TH1 and TH2 cells

(2009) Sara Trifari et al.   NATURE IMMUNOLOGY

Production of interleukin 22 but not interleukin 17 by a subset of human skin-homing memory T cells

(2009) Thomas Duhen et al.   NATURE IMMUNOLOGY

Th17 Cell Differentiation: The Long and Winding Road

(2008) Mandy J. McGeachy et al.   IMMUNITY

Aberrant expression of IL-22 receptor 1 and autocrine IL-22 stimulation contribute to tumorigenicity in ALK+ anaplastic large cell lymphoma

(2008) J Dien Bard et al.   LEUKEMIA

Kinetics, function and bone marrow trafficking of CD4+CD25+FOXP3+ regulatory T cells in myelodysplastic syndromes (MDS)

(2008) I Kotsianidis et al.   LEUKEMIA

A critical function for transforming growth factor-β, interleukin 23 and proinflammatory cytokines in driving and modulating human TH-17 responses

(2008) Elisabetta Volpe et al.   NATURE IMMUNOLOGY