Urocortin 3 Marks Mature Human Primary and Embryonic Stem Cell-Derived Pancreatic Alpha and Beta Cells

Functional beta-cell maturation is marked by an increased glucose threshold and by expression of urocortin 3

(2012) Barak Blum et al.   NATURE BIOTECHNOLOGY

A Scalable System for Production of Functional Pancreatic Progenitors from Human Embryonic Stem Cells

(2012) Thomas C. Schulz et al.   PLoS One

Stage-specific signaling through TGF  family members and WNT regulates patterning and pancreatic specification of human pluripotent stem cells

(2011) M. C. Nostro et al.   DEVELOPMENT

Multipotent stem/progenitor cells in human biliary tree give rise to hepatocytes, cholangiocytes, and pancreatic islets

(2011) Vincenzo Cardinale et al.   HEPATOLOGY

Cell-surface markers for the isolation of pancreatic cell types derived from human embryonic stem cells

(2011) Olivia G Kelly et al.   NATURE BIOTECHNOLOGY

Alpha cells secrete acetylcholine as a non-neuronal paracrine signal priming beta cell function in humans

(2011) Rayner Rodriguez-Diaz et al.   NATURE MEDICINE

Stem cell approaches for diabetes: towards beta cell replacement

(2011) Gordon C Weir et al.   Genome Medicine

Production of Functional Glucagon-Secreting  -Cells From Human Embryonic Stem Cells

(2010) A. Rezania et al.   DIABETES

Glucocorticoids Differentially Regulate the Expression of CRFR1 and CRFR2α in MIN6 Insulinoma Cells and Rodent Islets

(2010) M. O. Huising et al.   ENDOCRINOLOGY

Current Status of Islet Cell Replacement and Regeneration Therapy

(2010) Philippe A. Halban et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Conversion of adult pancreatic α-cells to β-cells after extreme β-cell loss

(2010) Fabrizio Thorel et al.   NATURE

Pancreatic β-Cell Neogenesis by Direct Conversion from Mature α-Cells

(2010) Cheng-Ho Chung et al.   STEM CELLS

Pancreatic islet plasticity: Interspecies comparison of islet architecture and composition

(2010) Donald J. Steiner et al.   Islets

The Ectopic Expression of Pax4 in the Mouse Pancreas Converts Progenitor Cells into α and Subsequently β Cells

(2009) Patrick Collombat et al.   CELL

Highly efficient differentiation of human ES cells and iPS cells into mature pancreatic insulin-producing cells

(2009) Donghui Zhang et al.   CELL RESEARCH

Neurogenin3 Is Sufficient for Transdetermination of Hepatic Progenitor Cells into Neo-Islets In Vivo but Not Transdifferentiation of Hepatocytes

(2009) Vijay Yechoor et al.   DEVELOPMENTAL CELL

Adult mouse intrahepatic biliary epithelial cells induced in vitro to become insulin-producing cells

(2009) Masaki Nagaya et al.   JOURNAL OF ENDOCRINOLOGY

The Transcriptional Response of the Islet to Pregnancy in Mice

(2009) Sebastian Rieck et al.   MOLECULAR ENDOCRINOLOGY

CRFR1 is expressed on pancreatic   cells, promotes   cell proliferation, and potentiates insulin secretion in a glucose-dependent manner

(2009) M. O. Huising et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

In vivo reprogramming of adult pancreatic exocrine cells to β-cells

(2008) Qiao Zhou et al.   NATURE

Pancreatic endoderm derived from human embryonic stem cells generates glucose-responsive insulin-secreting cells in vivo

(2008) Evert Kroon et al.   NATURE BIOTECHNOLOGY

Isolation of major pancreatic cell types and long-term culture-initiating cells using novel human surface markers

(2008) Craig Dorrell et al.   Stem Cell Research

Urocortins: emerging metabolic and energy homeostasis perspectives

(2008) Yael Kuperman et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM