HIV Protease Inhibitors Do Not Cause the Accumulation of Prelamin A in PBMCs from Patients Receiving First Line Therapy: The ANRS EP45 “Aging” Study

HIV-1 Infection and First Line ART Induced Differential Responses in Mitochondria from Blood Lymphocytes and Monocytes: The ANRS EP45 “Aging” Study

(2012) Sophie Perrin et al.   PLoS One

LMNA Mutations Induce a Non-Inflammatory Fibrosis and a Brown Fat-Like Dystrophy of Enlarged Cervical Adipose Tissue

(2011) Véronique Béréziat et al.   AMERICAN JOURNAL OF PATHOLOGY

Premature Age-Related Comorbidities Among HIV-Infected Persons Compared With the General Population

(2011) G. Guaraldi et al.   CLINICAL INFECTIOUS DISEASES

Antiretroviral drug toxicity in relation to pharmacokinetics, metabolic profile and pharmacogenetics

(2011) Mona Arab-Alameddine et al.   Expert Opinion on Drug Metabolism & Toxicology

High prevalence of laminopathies among patients with metabolic syndrome

(2011) Anne Dutour et al.   HUMAN MOLECULAR GENETICS

Lipodystrophies: Genetic and Acquired Body Fat Disorders

(2011) Abhimanyu Garg   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Tissue Says Blood Is Misleading, Confusing HIV Cure Efforts

(2011) J. Cohen   SCIENCE

Penetration of Tenofovir and Emtricitabine in Mucosal Tissues: Implications for Prevention of HIV-1 Transmission

(2011) K. B. Patterson et al.   Science Translational Medicine

HIV Infection, Inflammation, Immunosenescence, and Aging

(2010) Steven G. Deeks   Annual Review of Medicine

Premature Senescence of Vascular Cells Is Induced by HIV Protease Inhibitors

(2010) Chloé Lefèvre et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Prelamin A Acts to Accelerate Smooth Muscle Cell Senescence and Is a Novel Biomarker of Human Vascular Aging

(2010) Cassandra D. Ragnauth et al.   CIRCULATION

HIV protease inhibitors are substrates for OATP1A2, OATP1B1 and OATP1B3 and lopinavir plasma concentrations are influenced by SLCO1B1 polymorphisms

(2010) Ruben C. Hartkoorn et al.   Pharmacogenetics and Genomics

Dynamics of Lamin-A Processing Following Precursor Accumulation

(2010) Qian Liu et al.   PLoS One

Antiretroviral Tissue Kinetics: In Vivo Imaging Using Positron Emission Tomography

(2009) M. Di Mascio et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Intracellular Pharmacokinetics of Antiretroviral Drugs in HIV-Infected Patients, and their Correlation with Drug Action

(2009) Caroline Bazzoli et al.   CLINICAL PHARMACOKINETICS

Role of A-type lamins in signaling, transcription, and chromatin organization

(2009) Vicente Andrés et al.   JOURNAL OF CELL BIOLOGY

Nuclear lamins: key regulators of nuclear structure and activities

(2009) Miron Prokocimer et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

HIV-protease inhibitors block the enzymatic activity of purified Ste24p

(2008) Sarah E. Hudon et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Cultured CD4T cells and primary human lymphocytes express hOATPs: intracellular accumulation of saquinavir and lopinavir

(2008) O Janneh et al.   BRITISH JOURNAL OF PHARMACOLOGY

Nuclear lamins: major factors in the structural organization and function of the nucleus and chromatin

(2008) T. Dechat et al.   GENES & DEVELOPMENT

A Potent HIV Protease Inhibitor, Darunavir, Does Not Inhibit ZMPSTE24 or Lead to an Accumulation of Farnesyl-prelamin A in Cells

(2008) Catherine Coffinier et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Expression levels of MDR1, MRP1, MRP4, and MRP5 in peripheral blood mononuclear cells from HIV infected patients failing antiretroviral therapy

(2008) Ombretta Turriziani et al.   JOURNAL OF MEDICAL VIROLOGY

Combined treatment with statins and aminobisphosphonates extends longevity in a mouse model of human premature aging

(2008) Ignacio Varela et al.   NATURE MEDICINE

Design of HIV Protease Inhibitors Targeting Protein Backbone: An Effective Strategy for Combating Drug Resistance

(2007) Arun K. Ghosh et al.   ACCOUNTS OF CHEMICAL RESEARCH