ScFv Anti-Heparan Sulfate Antibodies Unexpectedly Activate Endothelial and Cancer Cells through p38 MAPK: Implications for Antibody-Based Targeting of Heparan Sulfate Proteoglycans in Cancer

Glycosaminoglycans: key players in cancer cell biology and treatment

(2012) Nikos Afratis et al.   FEBS Journal

Accumulating Microglia Phagocytose Injured Neurons in Hippocampal Slice Cultures: Involvement of p38 MAP Kinase

(2012) Takahiro Katayama et al.   PLoS One

Heparan Sulfate Proteoglycans Mediate the Angiogenic Activity of the Vascular Endothelial Growth Factor Receptor-2 Agonist Gremlin

(2011) Paola Chiodelli et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

SST0001, a Chemically Modified Heparin, Inhibits Myeloma Growth and Angiogenesis via Disruption of the Heparanase/Syndecan-1 Axis

(2011) Joseph P. Ritchie et al.   CLINICAL CANCER RESEARCH

A Novel Function of p38-Regulated/Activated Kinase in Endothelial Cell Migration and Tumor Angiogenesis

(2011) N. Yoshizuka et al.   MOLECULAR AND CELLULAR BIOLOGY

M402, a Novel Heparan Sulfate Mimetic, Targets Multiple Pathways Implicated in Tumor Progression and Metastasis

(2011) He Zhou et al.   PLoS One

Antibodies in Single-Chain Format Against Tumour-Associated Antigens:Present and Future Applications

(2010) L. Accardi et al.   CURRENT MEDICINAL CHEMISTRY

Proteoglycans in health and disease: novel roles for proteoglycans in malignancy and their pharmacological targeting

(2010) Achilleas D. Theocharis et al.   FEBS Journal

Establishment of heparan sulphate deficient primary endothelial cells from EXT-1flox/flox mouse lungs and sprouting aortas

(2010) Paulina Kucharzewska et al.   IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL

Antiangiogenic Activity of a Neutralizing Human Single-Chain Antibody Fragment against Fibroblast Growth Factor Receptor 1

(2010) R. Ronca et al.   MOLECULAR CANCER THERAPEUTICS

Magnetic nanoparticle-based isolation of endocytic vesicles reveals a role of the heat shock protein GRP75 in macromolecular delivery

(2010) A. Wittrup et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

ScFv Antibody-induced Translocation of Cell-surface Heparan Sulfate Proteoglycan to Endocytic Vesicles

(2009) Anders Wittrup et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Targeting of Tumor Blood Vessels: A Phage-Displayed Tumor-Homing Peptide Specifically Binds to Matrix Metalloproteinase-2-Processed Collagen IV and Blocks Angiogenesis In vivo

(2009) J. Mueller et al.   MOLECULAR CANCER RESEARCH

Tumor Angiogenesis

(2008) Robert S. Kerbel   NEW ENGLAND JOURNAL OF MEDICINE