Article
Medicine, General & Internal
Yeo Jin Kim, Ingyu Park, Hui-Chul Choi, Moo-Eob Ahn, Ohk-Hyun Ryu, Daehun Jang, Unjoo Lee, Sang-Kyu Lee
Summary: This study found an association between gait disturbances and cognitive function in patients with mild cognitive impairment. Gait characteristics such as velocity, step count, step length, and duration of swing and stance phase were correlated with cognitive impairment. Additionally, changes in gray matter volume and curvature in specific brain areas were also associated with gait characteristics related to cognitive dysfunction. Therefore, evaluating gait and cognitive functions is important in patients with mild cognitive impairment.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Computer Science, Artificial Intelligence
Mark Crook-Rumsey, Christina J. Howard, Zohreh Doborjeh, Maryam Doborjeh, Josafath Israel Espinosa Ramos, Nikola Kasabov, Alexander Sumich
Summary: Prospective memory (PM) is one of the first complaints in individuals with dementia-related diseases. The neurophysiology of PM in aging and mild cognitive impairment (MCI) is still not well understood. In this study, a novel artificial neural network (ANN) was used to investigate the spatial and temporal features of PM related brain activity and showed promising results in classifying brain activity between different age groups and individuals with MCI. The findings suggest that using PM related brain activity in combination with ANN can be a sensitive biomarker for detecting cognitive decline.
COGNITIVE COMPUTATION
(2023)
Review
Medicine, General & Internal
Giulia Marselli, Francesca Favieri, Maria Casagrande
Summary: Mild cognitive impairment (MCI) is a syndrome characterized by a decline in cognitive performance that exceeds what is expected for an individual based on their age and education level, but does not significantly interfere with daily activities. Previous studies have mainly focused on memory in the analysis of MCI and more severe cases of dementia. Autobiographical memory (AM), a specific memory system, has been extensively studied in Alzheimer's disease, but its impairment in MCI is still controversial.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Neuroimaging
Yu-Ling Chang, Ruei-Yi Chao, Yung-Chin Hsu, Ta-Fu Chen, Wen-Yih Isaac Tseng
Summary: This study investigated white matter microstructural integrity and cognitive correlates of memory awareness in older adults with or without mild cognitive impairment (MCI). While patients with MCI and poor awareness of memory deficits showed lower integrity in certain white matter fibers, the memory awareness deficits in MCI patients could not be solely explained by mnemonic anosognosia.
NEUROIMAGE-CLINICAL
(2021)
Article
Clinical Neurology
Egle Audronyte, Vaiva Sutnikiene, Gyte Pakulaite-Kazliene, Gintaras Kaubrys
Summary: This study investigated olfactory memory and its relationship with verbal memory and other clinical features in patients with early-stage Alzheimer's disease (AD). The results showed that olfactory memory was significantly impaired in patients with AD compared to individuals with mild cognitive impairment due to AD and cognitively normal older participants. Furthermore, the duration of AD symptoms was a strong predictor of olfactory recognition memory scores.
FRONTIERS IN NEUROLOGY
(2023)
Article
Neurosciences
Marco Calabria, Francesco Ciongoli, Nicholas Grunden, Celia Ordas, Carmen Garcia-Sanchez
Summary: Recent research has explored the effects of background music on memory performance in individuals with amnestic mild cognitive impairment (MCI). The findings suggest that while background music does not improve or worsen memory performance overall, individual preferences towards music and mood regulation play a role in the relationship between music and memory performance.
JOURNAL OF ALZHEIMERS DISEASE
(2023)
Article
Clinical Neurology
Christopher Malone, Katherine W. Turk, Rocco Palumbo, Andrew E. Budson
Summary: The study found that using deep encoding strategies alone or combining deep encoding with conservative strategies can improve gist memory and item-specific recollection in individuals with mild Alzheimer's disease, amnestic single-domain mild cognitive impairment, and healthy older adults. However, using conservative strategies alone may reduce performance in the MCI and OC groups. Patients with Alzheimer's disease were less able to benefit from these strategies, but could still use them to reduce unrelated memory errors and increase gist memory.
JOURNAL OF THE INTERNATIONAL NEUROPSYCHOLOGICAL SOCIETY
(2021)
Article
Behavioral Sciences
Giulia Giacomucci, Giulia Galdo, Cristina Polito, Valentina Berti, Sonia Padiglioni, Salvatore Mazzeo, Eleonora Chiaro, Maria Teresa De Cristofaro, Silvia Bagnoli, Benedetta Nacmias, Sandro Sorbi, Valentina Bessi
Summary: This study aims to assess empathy deficits and their neural correlates in patients with subjective cognitive decline (SCD), mild cognitive impairment (MCI), and Alzheimer's disease (AD) dementia. The study found that impairment of cognitive empathy starts at the MCI stage and extends to dementia. Increased emotional contagion may be related to dysfunction in specific brain regions.
BEHAVIOURAL BRAIN RESEARCH
(2022)
Article
Psychiatry
Claudia Frankenberg, Johannes Pantel, Uwe Haberkorn, Christina Degen, Monte S. Buchsbaum, Christina J. Herold, Johannes Schroeder
Summary: This study investigated changes in glucose metabolic rates in different cerebral sites in patients with Alzheimer's disease and mild cognitive impairment, and identified factors associated with autobiographical memory performance. The findings suggest that these changes may reflect both neurodegenerative processes and compensatory mechanisms in memory deficits.
FRONTIERS IN PSYCHIATRY
(2021)
Article
Psychology, Multidisciplinary
Ramon Lopez-Higes, Susana Rubio-Valdehita, Maria Luisa Delgado-Losada, David Lopez-Sanz
Summary: The study aimed to explore the relationships between cognitive reserve and different cognitive domains in older adults with subjective cognitive decline and mild cognitive impairment. The results showed that cognitive reserve strongly influences working memory, moderately influences sentence comprehension, but has little effect on episodic memory. In the patients' group, there is an inverse association between cognitive reserve and episodic memory.
CURRENT PSYCHOLOGY
(2023)
Article
Psychology, Clinical
Natascia De Lucia, Giovanni Carbone, Benedetta Muzii, Nicola Ferrara, Giuseppe Rengo, Nelson Mauro Maldonato, Grazia Daniela Femminella
Summary: This study aimed to evaluate the association between neuropsychiatric symptoms, cognitive function, regional tau deposition, and brain volumes in MCI subjects. The results showed that 61.4% of MCI subjects had at least one neuropsychiatric symptom, with depression, irritability, and sleep disturbances being the most prevalent. MCI subjects with neuropsychiatric symptoms showed significant differences in cognitive tests of frontal and executive functions and reduced brain volumes in the orbitofrontal and posterior cingulate cortices.
INTERNATIONAL PSYCHOGERIATRICS
(2023)
Article
Neurosciences
Taehyun Kim, Inho Shin, Sue-Hyun Lee
Summary: The study found that the confidence of false memories is related to shared representations with learned objects in the prefrontal cortex, while posterior regions are involved in processing perceptual gist.
Article
Psychology, Multidisciplinary
Yupaporn Rattanavichit, Nithinun Chaikeeree, Rumpa Boonsinsukh, Kasima Kitiyanant
Summary: Through a study of four groups of participants (early adults, middle adults, older adults, and older adults with probable MCI), it was found that cognitive inhibition declined earlier in middle adults, while executive function and perceptual-motor function started to decline in older adults. Cognitive flexibility was the only cognitive function that was sensitive to MCI.
FRONTIERS IN PSYCHOLOGY
(2022)
Article
Geriatrics & Gerontology
Yotam Lavy, Tzvi Dwolatzky, Zeev Kaplan, Jonathan Guez, Doron Todder
Summary: The study found that using an EEG-based neurofeedback system can significantly improve memory performance in patients with mild cognitive impairment (MCI), with this improvement lasting for at least one month.
FRONTIERS IN AGING NEUROSCIENCE
(2021)
Article
Neurosciences
Loris Naspi, Paul Hoffman, Barry Devereux, Alexa M. Morcom
Summary: The study found that both visual and semantic processing are crucial for accurate memory encoding, with neural patterns corresponding to low-level visual representations and fine-grained semantic feature representations predicting true recognition. Different representations in the brain contribute to successful memory encoding and avoiding false recognition errors.
JOURNAL OF NEUROSCIENCE
(2021)
Article
Engineering, Biomedical
Ian Daly, Duncan Williams, Alexis Kirke, James Weaver, Asad Malik, Faustina Hwang, Eduardo Miranda, Slawomir J. Nasuto
JOURNAL OF NEURAL ENGINEERING
(2016)
Article
Neurosciences
Catherine M. Sweeney-Reed, Tino Zaehle, Juergen Voges, Friedhelm C. Schmitt, Lars Buentjen, Viola Borchardt, Martin Walter, Hermann Hinrichs, Hans-Jochen Heinze, Michael D. Rugg, Robert T. Knight
FRONTIERS IN HUMAN NEUROSCIENCE
(2017)
Article
Neurosciences
Shijia Li, Liliana Ramona Demenescu, Catherine M. Sweeney-Reed, Anna Linda Krause, Coraline D. Metzger, Martin Walter
HUMAN BRAIN MAPPING
(2017)
Article
Clinical Neurology
Thomas Liebe, Shijia Li, Anton Lord, Lejla Colic, Anna Linda Krause, Anil Batra, Moritz A. Kretzschmar, Catherine M. Sweeney-Reed, Gusalija Behnisch, Bjoern H. Schott, Martin Walter
INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY
(2017)
Article
Behavioral Sciences
Viola Borchardt, Galina Surova, Johan van der Meer, Michal Bola, Joerg Frommer, Anna Linda Leutritz, Catherine M. Sweeney-Reed, Anna Buchheim, Bernhard Strauss, Tobias Nolte, Sebastian Olbrich, Martin Walter
BRAIN AND BEHAVIOR
(2018)
Article
Nutrition & Dietetics
Marc Pawlitzki, Julia Uebelhoer, Catherine M. Sweeney-Reed, Heike Stephanik, Juliane Hoffmann, Anke Lux, Dirk Reinhold
Article
Multidisciplinary Sciences
Henry Eberle, Slawomir J. Nasuto, Yoshikatsu Hayashi
SCIENTIFIC REPORTS
(2017)
Article
Engineering, Biomedical
Lars Buentjen, Andreas Kupsch, Imke Galazky, Roman Frantsev, Hans-Jochen Heinze, Juergen Voges, Janet Hausmann, Catherine M. Sweeney-Reed
JOURNAL OF NEUROENGINEERING AND REHABILITATION
(2019)
Article
Clinical Neurology
I Galazky, J. Kaufmann, J. Voges, H. Hinrichs, H-J Heinze, C. M. Sweeney-Reed
JOURNAL OF NEUROLOGY
(2019)
Article
Engineering, Biomedical
Amr Farahat, Christoph Reichert, Catherine M. Sweeney-Reed, Hermann Hinrichs
JOURNAL OF NEURAL ENGINEERING
(2019)
Article
Behavioral Sciences
Catherine M. Sweeney-Reed, Lars Buentjen, Jurgen Voges, Friedhelm C. Schmitt, Tino Zaehle, Julia W. Y. Kam, Jorn Kaufmann, Hans-Jochen Heinze, Hermann Hinrichs, Robert T. Knight, Michael D. Rugg
Summary: The extensive neuroanatomical connectivity between the anterior thalamic nuclei (ATN), hippocampus, and neocortex suggests a role in memory processing, which has been supported by various studies. Recent electrophysiological recordings from ATN in patients undergoing deep brain stimulation surgery have provided insights into the active role of ATN in memory encoding.
NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS
(2021)
Article
Health Care Sciences & Services
Catherine M. Sweeney-Reed, Doreen Wolff, Jakob Niggel, Michael Kabesch, Christian Apfelbacher
Summary: The study aims to evaluate the feasibility of an infection monitoring program in schools as an alternative to school closures, focusing on gargle samples and PCR pool testing procedures. The study emphasizes logistical support and family experiences for a comprehensive assessment of the approach's feasibility.
JMIR RESEARCH PROTOCOLS
(2021)
Article
Neurosciences
Angela Voegtle, Christoph Reichert, Hermann Hinrichs, Catherine M. Sweeney-Reed
Summary: Transcranial direct current stimulation (TDCS) is a technique that modulates neuronal activity by applying weak electrical currents to the scalp. Research has found that repetitive anodal TDCS can have a modulatory effect on working memory. In this study, 20 healthy participants underwent single-session and repetitive anodal TDCS, and it was found that repetitive TDCS increased the P300 amplitude, which positively correlated with task performance.
Article
Clinical Neurology
Marc Pawlitzki, Jens Neumann, Joern Kaufmann, Jan Heidel, Erhard Stadler, Catherine Sweeney-Reed, Michael Sailer, Stefanie Schreiber
NEUROLOGY-NEUROIMMUNOLOGY & NEUROINFLAMMATION
(2017)
Article
Mathematics, Interdisciplinary Applications
Catherine M. Sweeney-Reed, Slawomir J. Nasuto, Marcus F. Vieira, Adriano O. Andrade
ADVANCES IN DATA SCIENCE AND ADAPTIVE ANALYSIS
(2018)