Enterovirus RNA in Peripheral Blood May Be Associated with the Variants of rs1990760, a Common Type 1 Diabetes Associated Polymorphism in IFIH1

Type 1 Diabetes Is Associated With Enterovirus Infection in Gut Mucosa

(2012) M. Oikarinen et al.   DIABETES

MDA5 cooperatively forms dimers and ATP-sensitive filaments upon binding double-stranded RNA

(2012) Ian C Berke et al.   EMBO JOURNAL

Immunology in the clinic review series; focus on type 1 diabetes and viruses: the enterovirus link to type 1 diabetes: critical review of human studies

(2011) L. C. Stene et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Polymorphisms in the Innate Immune IFIH1 Gene, Frequency of Enterovirus in Monthly Fecal Samples during Infancy, and Islet Autoimmunity

(2011) Elisabet Witsø et al.   PLoS One

Enterovirus RNA in Blood Is Linked to the Development of Type 1 Diabetes

(2010) S. Oikarinen et al.   DIABETES

Loss-of-function mutations E6 27X and I923V of IFIH1 are associated with lower poly(I:C)–induced interferon-β production in peripheral blood mononuclear cells of type 1 diabetes patients

(2010) Dimitry A. Chistiakov et al.   HUMAN IMMUNOLOGY

Study of Transcriptional Effects in Cis at the IFIH1 Locus

(2010) Hana Zouk et al.   PLoS One

Reduced Expression of IFIH1 Is Protective for Type 1 Diabetes

(2010) Kate Downes et al.   PLoS One

Detection of Enterovirus RNA in Peripheral Blood Mononuclear Cells of Type 1 Diabetic Patients Beyond the Stage of Acute Infection

(2010) Barbara M. Schulte et al.   VIRAL IMMUNOLOGY

Interferon Induced with Helicase C Domain 1 (IFIH1) and Virus-Induced Autoimmunity: A Review

(2010) Dimitry A. Chistiakov   VIRAL IMMUNOLOGY

The interferon-induced helicase IFIH1 Ala946Thr polymorphism is associated with type 1 diabetes in both the high-incidence Finnish and the medium-incidence Hungarian populations

(2009) A. Jermendy et al.   DIABETOLOGIA

The prevalence of enteroviral capsid protein vp1 immunostaining in pancreatic islets in human type 1 diabetes

(2009) S. J. Richardson et al.   DIABETOLOGIA

IFIH1 gene polymorphisms in type 1 diabetes: Genetic association analysis and genotype–phenotype correlation in the Belgian population

(2009) Folefac Aminkeng et al.   HUMAN IMMUNOLOGY

Identification of Loss of Function Mutations in Human Genes Encoding RIG-I and MDA5

(2009) Taeko Shigemoto et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Multiple sclerosis and polymorphisms of innate pattern recognition receptors TLR1-10, NOD1-2, DDX58, and IFIH1

(2009) Christian Enevold et al.   JOURNAL OF NEUROIMMUNOLOGY

Rare Variants of IFIH1, a Gene Implicated in Antiviral Responses, Protect Against Type 1 Diabetes

(2009) S. Nejentsev et al.   SCIENCE

Analysis of pancreas tissue in a child positive for islet cell antibodies

(2008) M. Oikarinen et al.   DIABETOLOGIA

IFIH1-GCA-KCNH7 locus: influence on multiple sclerosis risk

(2008) Alfonso Martínez et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

The C-Terminal Regulatory Domain Is the RNA 5′-Triphosphate Sensor of RIG-I

(2008) Sheng Cui et al.   MOLECULAR CELL