Article
Infectious Diseases
Samantha R. Hewett, Stephany D. Crabtrey, Esther E. Dodson, C. Alexander Rieth, Richard M. Tarkka, Kari Naylor
Summary: Postoperative infections are a major concern in US hospitals, especially due to drug-resistant bacteria. Manuka honey from New Zealand has been approved by the FDA for wound treatment. This study aimed to find alternative types of honey that can specifically target antibiotic-resistant bacteria in wound infections. The study revealed that fresh raw Arkansas wildflower honey can comparably inhibit the growth of antibiotic-resistant bacteria, similar to manuka honey.
Article
Immunology
Jiawei Liang, Mowalolaoluwa Adeleye, Laura A. Onyango
Summary: This study demonstrates the synergistic effect of Manuka honey combined with antibiotics on Staphylococcus aureus, enhancing sensitivity to antibiotics and inhibiting the development of the SCV phenotype.
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY
(2023)
Article
Ecology
Brendan A. Daisley, Andrew P. Pitek, Christina Torres, Robin Lowery, Bethany A. Adair, Kait F. Al, Bernardo Nino, Jeremy P. Burton, Emma Allen-Vercoe, Graham J. Thompson, Gregor Reid, Elina Nino
Summary: Optimizing delivery methods can effectively apply beneficial lactobacilli consortium (LX3) to protect honey bees and promote hive health, resulting in increased brood production and colony growth.
Article
Pharmacology & Pharmacy
Jingru Shi, Chen Chen, Dejuan Wang, Ziwen Tong, Zhiqiang Wang, Yuan Liu
Summary: The study demonstrated that peptide WW307 displayed potent antibacterial activity against MDR bacteria, especially MRSA and Gram-negative pathogens carrying bla(NDM-5), mcr-1 or tet(X4). Additionally, WW307 showed great biofilm inhibition and eradication activity. Safety and stability experiments also indicated that WW307 had potential as a candidate for combating MDR pathogens.
Article
Food Science & Technology
Juraj Majtan, Marcela Bucekova, Ioannis Kafantaris, Piotr Szweda, Katherine Hammer, Dimitris Mossialos
Summary: Honey is considered a functional food with health-promoting properties, primarily due to its potent antibacterial and antibiofilm effects. Current honey quality parameters adopted in the European Union do not include biological properties, highlighting the need for revision and establishment of more effective quality control measures. The importance and efficacy of honey as an antibacterial agent is supported by in vitro and in vivo experiments, as well as human clinical studies.
TRENDS IN FOOD SCIENCE & TECHNOLOGY
(2021)
Article
Microbiology
Soeren M. M. Schuler, Gerrit Juerjens, Alexander Marker, Ulrike Hemmann, Astrid Rey, Stephane Yvon, Marjorie Lagrevol, Mohamed Hamiti, Fabian Nguyen, Rolf Hirsch, Christoph Poeverlein, Andreas Vilcinskas, Peter Hammann, Daniel N. Wilson, Michael Mourez, Sebastien Coyne, Armin Bauer
Summary: After the first total synthesis and structure revision, we thoroughly studied the tetrapeptide GE81112A, which is underexplored. Through in vitro and in vivo profiling, we identified the critical parameters and limitations of the compound, providing a basis for further optimization and development of potential antibiotics.
MICROBIOLOGY SPECTRUM
(2023)
Article
Materials Science, Paper & Wood
Lamyaa M. Kassem, Ahmed G. El-Deen, A. H. Zaki, S. I. El-Dek
Summary: The major challenge in skin tissue engineering is creating suitable extracellular matrix (ECM) scaffolds. A nanofibrous scaffold, made from a manuka honey-treated polyvinyl pyrrolidine (Mh@PVP) composite, was successfully electrospun to aid in ECM growth and drug delivery. Different characterizations were used to analyze the fabricated electrospun nanofibrous scaffolds. Increasing the concentration of manuka honey in the formula improved the mechanical properties of the polyvinyl pyrrolidine (PVP) solutions. The nanofiber scaffold showed potential for rapid and substantial wound healing.
Article
Polymer Science
Dongwei Lan, Yuqin Zhang, Haiqiang Zhang, Jiale Zhou, Xiang Chen, Zhi Li, Fangyin Dai
Summary: The novel wound dressing prepared by mixing natural Manuka honey, silk fibroin, and polycaprolactone showed excellent antimicrobial properties and cytocompatibility, offering potential for accelerating wound healing.
JOURNAL OF APPLIED POLYMER SCIENCE
(2022)
Article
Biochemistry & Molecular Biology
Isaac Rodriguez, Tricia Conti, Nina Bionda
Summary: This study compared the effects of three commercially available wound care products on inflammatory reduction and growth factor production. The results showed that the BCMH product had lower levels of inflammation and higher levels of growth factor expression, suggesting it provided a better comprehensive approach to wound progression.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Polymer Science
Karina Mitchell, Sreejith S. Panicker, Calista L. Adler, George A. O'Toole, Katherine R. Hixon
Summary: Honey has been used for centuries to reduce bacterial infection, and Manuka honey with Unique Manuka Factor (UMF) possesses additional antibacterial properties. This study investigated the incorporation of Manuka honey into chitosan-gelatin cryogels and hydrogels, finding that lower concentrations showed improved bacterial clearance while higher concentrations resulted in cell death.
Article
Microbiology
Diletta Collalto, Alessandra Fortuna, Paolo Visca, Francesco Imperi, Giordano Rampioni, Livia Leoni
Summary: Co-administration of colistin and clofoctol enhances the bactericidal effect of colistin and reduces the minimum inhibitory concentration (MIC) of colistin in resistant strains. This study suggests the potential development of inhaled clofoctol-colistin formulations for the treatment of difficult-to-treat airway infections caused by drug-resistant Gram-negative pathogens.
MICROBIOLOGY SPECTRUM
(2023)
Article
Biotechnology & Applied Microbiology
Glaucia Morgana de Melo Guedes, Alyne Soares Freitas, Rodrigo Machado Pinheiro, Vinicius Carvalho Pereira, Carliane Melo Alves Melgarejo, Emanuela Silva de Araujo, Kesia Veras Costa Ribeiro, Silviane Praciano Bandeira, Rossana de Aguiar Cordeiro, Marcos Fabio Gadelha Rocha, Jose Julio Costa Sidrim, Debora de Souza Collares Maia Castelo-Branco
Summary: This study evaluated the antibiofilm activity of promethazine, deferiprone, and Manuka honey against Staphylococcus aureus and Pseudomonas aeruginosa. The compounds were found to have inhibitory and eradication effects on biofilms. Furthermore, they significantly reduced bacterial counts and altered the structure of biofilms in ex vivo experiments.
LETTERS IN APPLIED MICROBIOLOGY
(2023)
Article
Nutrition & Dietetics
Juliana Garcia, Francisca Rodrigues, Flavia Castro, Alfredo Aires, Guilhermina Marques, Maria Jose Saavedra
Summary: The aqueous and methanolic extracts of Boletus edulis and Neoboletus luridiformis have antimicrobial and antibiofilm properties against multidrug-resistant bacteria, possibly due to the presence of phenolic compounds.
FRONTIERS IN NUTRITION
(2022)
Article
Infectious Diseases
Sarah V. Harding, Kay B. Barnes, Stephen Hawser, Christine E. Bentley, Andreas Vente
Summary: This study examined the effectiveness of finafloxacin against bacterial strains associated with infections in cystic fibrosis patients, with a focus on respiratory diseases. Many of the strains tested were resistant to common antimicrobial drugs. However, finafloxacin showed superior activity at lower pH, emphasizing the importance of testing antimicrobials in conditions relevant to the host.
Article
Veterinary Sciences
Muhammad Fakhar-e-Alam Kulyar, Khurram Ashfaq, Amjad Islam Aqib, Kun Duan, Muhammad Asif, Zeeshan Ahmad Bhutta, Muhammad Shoaib, Samina Shabbir, Shah Nawaz, Muhammad Aamir Naseer, Iqra Sarwar, Muhammad Akhtar, Ayesha Safdar Chaudhry, Riaz Hussain, Hafiz Iftikhar Hussain, Yi Wu, Kun Li
Summary: The study found that the combination of Manuka honey and Nitrofurazone ointments had better therapeutic effects on full-thickness burn wounds in rabbits, leading to faster healing and improved recovery. Additionally, changes in blood cell count and quality were observed during the treatment process.
FRONTIERS IN VETERINARY SCIENCE
(2022)
Article
Microbiology
Rowena Jenkins, Mandy Wootton, Robin Howe, Rose Cooper
ARCHIVES OF MICROBIOLOGY
(2015)
Article
Biotechnology & Applied Microbiology
K. L. Hillitt, R. E. Jenkins, O. B. Spiller, M. L. Beeton
LETTERS IN APPLIED MICROBIOLOGY
(2017)
Article
Infectious Diseases
A. F. Henriques, R. E. Jenkins, N. F. Burton, R. A. Cooper
EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES
(2010)
Article
Infectious Diseases
A. F. Henriques, R. E. Jenkins, N. F. Burton, R. A. Cooper
EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES
(2011)
Editorial Material
Infectious Diseases
Rose Cooper, Rowena Jenkins
EXPERT REVIEW OF ANTI-INFECTIVE THERAPY
(2012)
Article
Microbiology
Sarah Elizabeth Maddocks, Rowena Eleri Jenkins, Richard Samuel Rowlands, Kevin John Purdy, Rose Agnes Cooper
FUTURE MICROBIOLOGY
(2013)
Review
Microbiology
Sarah E. Maddocks, Rowena E. Jenkins
FUTURE MICROBIOLOGY
(2013)
Article
Infectious Diseases
Rowena Jenkins, Neil Burton, Rose Cooper
INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS
(2011)
Letter
Infectious Diseases
Rowena Jenkins, Mandy Wootton, Robin Howe, Rose Cooper
INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS
(2012)
Article
Infectious Diseases
Rowena Jenkins, Neil Burton, Rose Cooper
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
(2011)
Article
Infectious Diseases
Rowena E. Jenkins, Rose Cooper
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
(2012)
Article
Infectious Diseases
Rowena Jenkins, Neil Burton, Rose Cooper
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
(2014)
Article
Microbiology
Aled E. L. Roberts, Lydia C. Powell, Manon F. Pritchard, David W. Thomas, Rowena E. Jenkins
FRONTIERS IN MICROBIOLOGY
(2019)
Article
Immunology
Abdullah A. Alangari, Keith Morris, Bashir A. Lwaleed, Laurie Lau, Ken Jones, Rose Cooper, Rowena Jenkins
IMMUNITY INFLAMMATION AND DISEASE
(2017)