Article
Nutrition & Dietetics
Tyler Maher, Martina Deleuse, Sangeetha Thondre, Amir Shafat, Miriam E. Clegg
Summary: There is inconsistent evidence for greater satiety after consuming medium-chain triglycerides (MCT) compared to long-chain triglycerides (LCT). This study compared appetite responses in individuals with healthy weight and overweight/obesity after consuming MCT or conjugated linoleic acid (CLA). The results showed that MCT reduced energy intake over a 48-hour period, possibly due to delayed gastric emptying and increased beta-hydroxybutyrate concentrations.
EUROPEAN JOURNAL OF NUTRITION
(2021)
Article
Endocrinology & Metabolism
Matthew M. Hurley, Kimberly R. Smith, Civonnia Harris, Ethan J. Goodman, Susan Carnell, Vidyulata Kamath, Timothy H. Moran, Kimberley E. Steele
Summary: This study investigates the relationship between gut hormone secretion and taste preferences following bariatric surgery. The study finds significant changes in gut hormone secretion after surgery, and the liking ratings for taste mixtures are mainly related to mixtures containing both fat and sugar. These findings contribute to a better understanding of the mechanisms underlying weight loss after bariatric surgery.
INTERNATIONAL JOURNAL OF OBESITY
(2022)
Article
Endocrinology & Metabolism
Yigit Unlu, Karyne L. Vinales, Tim Hollstein, Douglas Chang, Tomas Cabeza de Baca, Mary Walter, Jonathan Krakoff, Paolo Piaggi
Summary: This study investigated the relationship between interindividual variance in diet-induced metabolic flexibility and differences in gut hormone concentrations. The findings suggest that increased GLP-1 concentration following high-carbohydrate overfeeding is associated with a greater shift to carbohydrate oxidation.
Article
Food Science & Technology
Martin Gotteland, Alejandra Zazueta, Jose Luis Pino, Andrea Fresard, Veronica Sambra, Juana Codoceo, Maria Jose Cires, Ximena Lopez, Juan Pablo Vivanco, Fabien Magne
Summary: Cereal beta-glucans have positive effects on cholesterolemia, glycaemia, digestive hormones, and gut microbiota. Acute intake of 5 g beta-glucan from oats slows transit time, decreases hunger sensation and postprandial glycaemia, and alters hormone levels without affecting bile-acid synthesis. However, regular daily intake of 3 g beta-glucan does not have an effect on fecal microbiota composition.
Article
Nutrition & Dietetics
Marion E. C. Buso, Radhika V. Seimon, Sally McClintock, Roslyn Muirhead, Fiona S. Atkinson, Shannon Brodie, Jarron Dodds, Jessica Zibellini, Arpita Das, Anthony L. Wild-Taylor, Jessica Burk, Mikael Fogelholm, Anne Raben, Jennie C. Brand-Miller, Amanda Sainsbury
Summary: The study found that a higher-protein, low-GI diet for weight maintenance does not attenuate changes in ghrelin or peptide YY compared with a moderate-protein, moderate-GI diet. Subjective appetite sensations were not affected by the weight-reducing diet nor the weight-maintenance diets. While participants regained an average of similar to 50% of the weight they had lost by 36 months, the changes in ghrelin and peptide YY during the weight-reducing phase did not correlate with weight regain.
FRONTIERS IN NUTRITION
(2021)
Review
Nutrition & Dietetics
Habeeb Alhabeeb, Ali AlFaiz, Emad Kutbi, Dayel AlShahrani, Abdullah Alsuhail, Saleh AlRajhi, Nemer Alotaibi, Khalid Alotaibi, Saad AlAmri, Saleh Alghamdi, Naji AlJohani
Summary: Global obesity rates have tripled since 1975, making it a major risk factor for non-communicable diseases. Urgent action is needed to develop more effective treatments and interventions for obesity.
Article
Nutrition & Dietetics
Edward G. Walker, Kim R. Lo, Malcolm C. Pahl, Hyun S. Shin, Claudia Lang, Mark W. Wohlers, Sally D. Poppitt, Kevin H. Sutton, John R. Ingram
Summary: Hop extract can regulate energy intake, appetite, and hormonal responses in healthy-weight men, providing a potential way to control appetite and improve glycemic regulation. However, it may cause mild gastrointestinal discomfort.
AMERICAN JOURNAL OF CLINICAL NUTRITION
(2022)
Review
Biochemistry & Molecular Biology
Ryogo Shobatake, Hiroyo Ota, Nobuyuki Takahashi, Satoshi Ueno, Kazuma Sugie, Shin Takasawa
Summary: Sleep apnea syndrome (SAS) is associated with intermittent hypoxia (IH) during sleep, which can affect insulin secretion and insulin resistance, potentially leading to obesity. The direct contribution of SAS to obesity is still debated. This review summarizes recent epidemiological findings on the relationship between SAS and feeding behavior, focusing on the effects of IH on the gut-brain axis.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Review
Multidisciplinary Sciences
Mingzhu Hu, Zhaowei Kong, Qingde Shi, Jinlei Nie
Summary: This systematic review and meta-analysis examined the impact of different exercise modalities on acylated ghrelin (AG), glucagon-like peptide-1 (GLP-1), and peptide YY (PYY). The results showed that high intensity interval training (HIIT)/sprint interval training (SIT) as well as moderate intensity continuous training (MICT) decreased AG concentration and increased GLP-1 and PYY concentration. Interval training, particularly SIT, had a greater effect in suppressing AG levels and increasing PYY immediately after exercise compared to MICT.
Review
Endocrinology & Metabolism
Jacco J. A. J. Bastings, Koen Venema, Ellen E. Blaak, Tanja C. Adam
Summary: Recent studies have found that there is a connection between the gut microbiota and the regulation of satiety and energy intake, which are important processes in the development and pathophysiology of metabolic diseases. However, most of this connection has been established through animal and in vitro studies, with human intervention studies being limited. In this review, the focus is on recent evidence linking satiety and the gut microbiome, particularly the role of short-chain fatty acids (SCFAs) produced by gut microbes. The review provides an overview of human studies that link the intake of prebiotics with changes in gut microbial composition and satiety signaling, emphasizing the need for further research in this field.
TRENDS IN ENDOCRINOLOGY AND METABOLISM
(2023)
Review
Neurosciences
Gordon B. Feld, Jan Born
NEUROPSYCHOPHARMACOLOGY
(2020)
Article
Neurosciences
Marjan Alizadeh Asfestani, Valentin Brechtmann, Joao Santiago, Andreas Peter, Jan Born, Gordon Benedikt Feld
JOURNAL OF COGNITIVE NEUROSCIENCE
(2020)
Editorial Material
Neurosciences
Niels Niethard, Jan Born
Article
Multidisciplinary Sciences
Luciana Besedovsky, Mona Benischke, Joerg Fischer, Amir S. Yazdi, Jan Born
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2020)
Article
Multidisciplinary Sciences
Manuela Friedrich, Matthias Moelle, Angela D. Friederici, Jan Born
NATURE COMMUNICATIONS
(2020)
Article
Clinical Neurology
Jules Schneider, Penelope A. Lewis, Dominik Koester, Jan Born, Hong-Viet V. Ngo
Article
Neurosciences
Carlos N. Oyanedel, Ernesto Duran, Niels Niethard, Marion Inostroza, Jan Born
EUROPEAN JOURNAL OF NEUROSCIENCE
(2020)
Article
Behavioral Sciences
Anuck Sawangjit, Carlos N. Oyanedel, Niels Niethard, Jan Born, Marion Inostroza
NEUROBIOLOGY OF LEARNING AND MEMORY
(2020)
Article
Biology
Cecilia Forcato, Jens G. Klinzing, Julia Carbone, Michael Radloff, Frederik D. Weber, Jan Born, Susanne Diekelmann
COMMUNICATIONS BIOLOGY
(2020)
Article
Neurosciences
Niels Niethard, Svenja Brodt, Jan Born
Summary: The study revealed that during slow-wave sleep, excitatory pyramidal cells showed decreased calcium activity, but the variance in activity increased, indicating a heterogeneous regulation of network activity. Some pyramidal cells exhibited increased calcium activity during slow-wave sleep, potentially involved in memory processing.
JOURNAL OF NEUROSCIENCE
(2021)
Article
Biology
Kathrin Thiede, Jan Born, Albrecht P. A. Vorster
Summary: Sleep is crucial for memory consolidation after learning, but may not be necessary for simple reflex conditioning. Extinction training did not reverse the enhanced response to the conditioned stimulus, and responses were further increased at the 48-hour test, suggesting a contribution of sensitization processes to the withdrawal response.
JOURNAL OF EXPERIMENTAL BIOLOGY
(2021)
Article
Biology
Luciana Besedovsky, Maren Cordi, Laura Wisslicen, Estefania Martinez-Albert, Jan Born, Bjoern Rasch
Summary: The use of hypnotic suggestions to enhance slow wave sleep (SWS) has been found to significantly affect the endocrine and autonomic nervous systems. Hypnotic suggestions can increase the release of growth hormone and shift the sympathovagal balance, leading to a whole-body pattern characteristic of natural SWS.
COMMUNICATIONS BIOLOGY
(2022)
Article
Multidisciplinary Sciences
Manuela Friedrich, Matthias Moelle, Jan Born, Angela D. Friederici
Summary: This study investigated the memory of nonadjacent dependencies in 6-8 month old infants and examined whether sleep after learning affects this memory. The results showed that infants were able to retain memory of nonadjacent dependencies regardless of whether they napped or stayed awake. However, napping did affect a specific processing stage, suggesting that memory evolves during sleep.
NATURE COMMUNICATIONS
(2022)
Article
Neurosciences
Maria P. Contreras, Julia Fechner, Jan Born, Marion Inostroza
Summary: Research shows that discrete spatial experience can accelerate the maturation of spatial memory systems in the brain. This maturation is driven by specific sleep oscillations, which contribute to the formation of long-term memory and knowledge. The findings suggest that experience plays a positive role in the development of memory systems.
JOURNAL OF NEUROSCIENCE
(2023)
Article
Multidisciplinary Sciences
Janna D. Lendner, Niels Niethard, Bryce A. Mander, Frank J. van Schalkwijk, Sigrid Schuh-Hofer, Hannah Schmidt, Robert T. Knight, Jan Born, Matthew P. Walker, Jack J. Lin, Randolph F. Helfrich
Summary: The study shows that non-oscillatory brain activity during REM sleep plays a key role in the sleep-dependent recalibration of neural population dynamics. The extent of REM sleep recalibration predicts the success of overnight memory consolidation by favoring remembering over forgetting. This non-oscillatory mechanism explains how REM sleep enhances long-term memory in humans.