Curcuminoid Binding to Embryonal Carcinoma Cells: Reductive Metabolism, Induction of Apoptosis, Senescence, and Inhibition of Cell Proliferation

The Targets of Curcumin

(2012) Hongyu Zhou et al.   CURRENT DRUG TARGETS

Curcumin enhanced antiproliferative effect of mitomycin C in human breast cancer MCF-7 cells in vitro and in vivo

(2011) Qian-mei Zhou et al.   ACTA PHARMACOLOGICA SINICA

STAT3 signaling pathway is necessary for cell survival and tumorsphere forming capacity in ALDH+/CD133+ stem cell-like human colon cancer cells

(2011) Li Lin et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Curcumin induces stress response and hormetically modulates wound healing ability of human skin fibroblasts undergoing ageing in vitro

(2011) Dino Demirovic et al.   BIOGERONTOLOGY

Curcumin induces a nuclear factor-erythroid 2-related factor 2-driven response against oxidative and nitrative stress after praziquantel treatment in liver fluke-infected hamsters

(2011) Lakhanawan Charoensuk et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY

The short-time treatment with curcumin sufficiently decreases cell viability, induces apoptosis and copper enhances these effects in multidrug-resistant K562/A02 cells

(2011) Jin-Jian Lu et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Curcumin: A review of anti-cancer properties and therapeutic activity in head and neck squamous cell carcinoma

(2011) Reason Wilken et al.   Molecular Cancer

Anticancer Activity of a Combination of Cisplatin and Fisetin in Embryonal Carcinoma Cells and Xenograft Tumors

(2011) R. Tripathi et al.   MOLECULAR CANCER THERAPEUTICS

Role of membrane dynamics processes and exogenous molecules in cellular resveratrol uptake: Consequences in bioavailability and activities

(2011) Dominique Delmas et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Failure of SOX9 Regulation in 46XY Disorders of Sex Development with SRY, SOX9 and SF1 Mutations

(2011) Kevin C. Knower et al.   PLoS One

Membrane Organization and Lipid Rafts

(2011) K. Simons et al.   Cold Spring Harbor Perspectives in Biology

Targeting Inflammation-Induced Obesity and Metabolic Diseases by Curcumin and Other Nutraceuticals

(2010) Bharat B. Aggarwal   Annual Review of Nutrition

Curcumin analogues exhibit enhanced growth suppressive activity in human pancreatic cancer cells

(2010) Lauren Friedman et al.   ANTI-CANCER DRUGS

Systematic analysis of the antiproliferative effects of novel and standard anticancer agents in rhabdoid tumor cell lines

(2010) Henning Lünenbürger et al.   ANTI-CANCER DRUGS

Curcumin as a therapeutic agent: the evidence from in vitro, animal and human studies

(2010) Jenny Epstein et al.   BRITISH JOURNAL OF NUTRITION

Curcumin disrupts meiotic and mitotic divisions via spindle impairment and inhibition of CDK1 activity

(2010) A. Bielak-Zmijewska et al.   CELL PROLIFERATION

Regulation of NF-κB signaling by caspases and MALT1 paracaspase

(2010) Jens Staal et al.   CELL RESEARCH

Curcumin Induces Cell Death in Human Uveal Melanoma Cells through Mitochondrial Pathway

(2010) Chengwei Lu et al.   CURRENT EYE RESEARCH

Regulation of DNA fragmentation: the role of caspases and phosphorylation

(2010) Ikuko Kitazumi et al.   FEBS Journal

Evaluation of in vitro anti-proliferative and immunomodulatory activities of compounds isolated from Curcuma longa

(2010) Grace G.L. Yue et al.   FOOD AND CHEMICAL TOXICOLOGY

Up-regulation of heme oxygenase-1 expression through CaMKII-ERK1/2-Nrf2 signaling mediates the anti-inflammatory effect of bisdemethoxycurcumin in LPS-stimulated macrophages

(2010) An Na Kim et al.   FREE RADICAL BIOLOGY AND MEDICINE

The essence of senescence

(2010) T. Kuilman et al.   GENES & DEVELOPMENT

Curcumin targeted signaling pathways: basis for anti-photoaging and anti-carcinogenic therapy

(2010) Madalene C.Y. Heng   INTERNATIONAL JOURNAL OF DERMATOLOGY

Hazardous Effects of Curcumin on Mouse Embryonic Development through a Mitochondria-Dependent Apoptotic Signaling Pathway

(2010) Chia-Chi Chen et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Curcuminoids Suppress the Growth and Induce Apoptosis through Caspase-3-Dependent Pathways in Glioblastoma Multiforme (GBM) 8401 Cells

(2010) Tzuu-Yuan Huang et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Transcriptional Upregulation of Nrf2-Dependent Phase II Detoxification Genes in the Involved Epidermis of Vitiligo Vulgaris

(2010) Vivek T. Natarajan et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Curcumin: a novel nutritionally derived ligand of the vitamin D receptor with implications for colon cancer chemoprevention

(2010) Leonid Bartik et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Coffee, broccoli and spices are strong inducers of electrophile response element-dependent transcription in vitro and in vivo - Studies in electrophile response element transgenic mice

(2010) Trude Rakel Balstad et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Curcumin Inhibits the Growth, Induces Apoptosis and Modulates the Function of Pituitary Folliculostellate Cells

(2010) Christian Schaaf et al.   NEUROENDOCRINOLOGY

Growth Suppression of Mouse Pituitary Corticotroph Tumor AtT20 Cells by Curcumin: A Model for Treating Cushing's Disease

(2010) Madhavi Latha Yadav Bangaru et al.   PLoS One

A Senescence-Like Cell-Cycle Arrest Occurs During Megakaryocytic Maturation: Implications for Physiological and Pathological Megakaryocytic Proliferation

(2010) Rodolphe Besancenot et al.   PLOS BIOLOGY

Curcumin and Cancer Cells: How Many Ways Can Curry Kill Tumor Cells Selectively?

(2009) Jayaraj Ravindran et al.   AAPS Journal

RETRACTED: Design of curcumin-loaded PLGA nanoparticles formulation with enhanced cellular uptake, and increased bioactivity in vitro and superior bioavailability in vivo

(2009) Preetha Anand et al.   BIOCHEMICAL PHARMACOLOGY

New structural analogues of curcumin exhibit potent growth suppressive activity in human colorectal carcinoma cells

(2009) Ling Cen et al.   BMC CANCER

Curcumin blocks brain tumor formation

(2009) Sudarshana Purkayastha et al.   BRAIN RESEARCH

Effect of curcumin on the proliferation and apoptosis of hepatic stellate cells

(2009) J.C. Shu et al.   BRAZILIAN JOURNAL OF MEDICAL AND BIOLOGICAL RESEARCH

Curcumin induces apoptosis-independent death in oesophageal cancer cells

(2009) G O'Sullivan-Coyne et al.   BRITISH JOURNAL OF CANCER

Cellular signaling perturbation by natural products

(2009) Fazlul H. Sarkar et al.   CELLULAR SIGNALLING

The Human Carnitine Transporter SLC22A16 Mediates High Affinity Uptake of the Anticancer Polyamine Analogue Bleomycin-A5

(2009) Mustapha Aouida et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Effective Stabilization of Curcumin by Association to Plasma Proteins: Human Serum Albumin and Fibrinogen

(2009) Mandy H. M. Leung et al.   LANGMUIR

Cell cycle inhibition and apoptosis induced by curcumin in Ewing sarcoma cell line SK-NEP-1

(2009) Mansher Singh et al.   MEDICAL ONCOLOGY

Curcumin inhibits cell proliferation of MDA-MB-231 and BT-483 breast cancer cells mediated by down-regulation of NFκB, cyclinD and MMP-1 transcription

(2009) Q. Liu et al.   PHYTOMEDICINE

Synthesis of novel biodegradable and self-assembling methoxy poly(ethylene glycol)–palmitate nanocarrier for curcumin delivery to cancer cells

(2008) Abhishek Sahu et al.   Acta Biomaterialia

Biological activities of curcumin and its analogues (Congeners) made by man and Mother Nature

(2008) Preetha Anand et al.   BIOCHEMICAL PHARMACOLOGY

Quantitative cellular uptake, localization and cytotoxicity of curcumin in normal and tumor cells

(2008) A. Kunwar et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Differential solubility of curcuminoids in serum and albumin solutions: implications for analytical and therapeutic applications

(2008) Wolfgang W Quitschke   BMC BIOTECHNOLOGY

Curcumin: From ancient medicine to current clinical trials

(2008) H. Hatcher et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Curcumin, a nutritional supplement with antineoplastic activity, enhances leiomyoma cell apoptosis and decreases fibronectin expression

(2008) Minnie Malik et al.   FERTILITY AND STERILITY

Plasma Membrane Proteomics of Human Embryonic Stem Cells and Human Embryonal Carcinoma Cells

(2008) Wilma Dormeyer et al.   JOURNAL OF PROTEOME RESEARCH

New mechanisms and therapeutic potential of curcumin for colorectal cancer

(2008) Isabel Villegas et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Metabolism of curcumin and induction of mitotic catastrophe in human cancer cells

(2008) Julia S. Dempe et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Isolation and Identification of an Anti-tumor Component from Leaves of Impatiens balsamina

(2008) Zhi-Shan Ding et al.   MOLECULES

Different Curcuminoids Inhibit T-Lymphocyte Proliferation Independently of Their Radical Scavenging Activities

(2008) Michael Deters et al.   PHARMACEUTICAL RESEARCH

Pharmacological basis for the role of curcumin in chronic diseases: an age-old spice with modern targets

(2008) Bharat B. Aggarwal et al.   TRENDS IN PHARMACOLOGICAL SCIENCES