Effect of Spermidine on Misfolding and Interactions of Alpha-Synuclein

Phosphorylation of α-Synuclein at Y125 and S129 Alters Its Metal Binding Properties: Implications for Understanding the Role of α-Synuclein in the Pathogenesis of Parkinson’s Disease and Related Disorders

(2011) Yu Lu et al.   ACS Chemical Neuroscience

Structural Role of Compensatory Amino Acid Replacements in the α-Synuclein Protein

(2011) Valeria Losasso et al.   BIOCHEMISTRY

Single-Molecule Atomic Force Microscopy Force Spectroscopy Study of Aβ-40 Interactions

(2011) Bo-Hyun Kim et al.   BIOCHEMISTRY

Single Molecule Characterization of α-Synuclein in Aggregation-Prone States

(2010) Adam J. Trexler et al.   BIOPHYSICAL JOURNAL

Polyamine pathway contributes to the pathogenesis of Parkinson disease

(2010) N. M. Lewandowski et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nanoimaging for protein misfolding diseases

(2010) Yuri L. Lyubchenko et al.   Wiley Interdisciplinary Reviews-Nanomedicine and Nanobiotechnology

Brain α-synuclein accumulation in multiple system atrophy, Parkinson's disease and progressive supranuclear palsy: a comparative investigation

(2009) Junchao Tong et al.   BRAIN

E46K Parkinson’s-Linked Mutation Enhances C-Terminal-to-N-Terminal Contacts in α-Synuclein

(2009) Carla C. Rospigliosi et al.   JOURNAL OF MOLECULAR BIOLOGY

Pathogenic Mutations Shift the Equilibria of α-Synuclein Single Molecules towards Structured Conformers

(2008) Marco Brucale et al.   CHEMBIOCHEM

Structural insights on physiological functions and pathological effects of α-synuclein

(2008) Marco Bisaglia et al.   FASEB JOURNAL

α-Synuclein Misfolding: Single Molecule AFM Force Spectroscopy Study

(2008) Junping Yu et al.   JOURNAL OF MOLECULAR BIOLOGY

Characterization of Conformational and Dynamic Properties of Natively Unfolded Human and Mouse α-Synuclein Ensembles by NMR: Implication for Aggregation

(2008) Kuen-Phon Wu et al.   JOURNAL OF MOLECULAR BIOLOGY

Solid-State NMR Reveals Structural Differences between Fibrils of Wild-Type and Disease-Related A53T Mutant α-Synuclein

(2008) Henrike Heise et al.   JOURNAL OF MOLECULAR BIOLOGY

Early Stages for Parkinson’s Development: α-Synuclein Misfolding and Aggregation

(2008) Junping Yu et al.   Journal of Neuroimmune Pharmacology

Spermine Binding to Parkinson’s Protein α-Synuclein and Its Disease-Related A30P and A53T Mutants

(2008) Megan Grabenauer et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Conformational Equilibria in Monomeric α-Synuclein at the Single-Molecule Level

(2008) Massimo Sandal et al.   PLOS BIOLOGY