Identification of Enriched Driver Gene Alterations in Subgroups of Non-Small Cell Lung Cancer Patients Based on Histology and Smoking Status

The role of LKB1 in lung cancer

(2011) Montse Sanchez-Cespedes   Familial Cancer

Molecular Selection Trumps Clinical Selection

(2011) Frances A. Shepherd   JOURNAL OF CLINICAL ONCOLOGY

Clinical Characteristics of Patients With Lung Adenocarcinomas HarboringBRAFMutations

(2011) Paul K. Paik et al.   JOURNAL OF CLINICAL ONCOLOGY

Relative Abundance of EGFR Mutations Predicts Benefit From Gefitinib Treatment for Advanced Non–Small-Cell Lung Cancer

(2011) Qing Zhou et al.   JOURNAL OF CLINICAL ONCOLOGY

Molecular biomarkers in non-small-cell lung cancer: a retrospective analysis of data from the phase 3 FLEX study

(2011) Kenneth J O'Byrne et al.   LANCET ONCOLOGY

New driver mutations in non-small-cell lung cancer

(2011) William Pao et al.   LANCET ONCOLOGY

Smoking history and lung carcinoma: KRAS mutation is an early hit in lung adenocarcinoma development

(2011) F.B. Thunnissen et al.   LUNG CANCER

Mutations in the DDR2 Kinase Gene Identify a Novel Therapeutic Target in Squamous Cell Lung Cancer

(2011) Peter S. Hammerman et al.   Cancer Discovery

LKB1 in lung cancerigenesis: a serine/threonine kinase as tumor suppressor

(2011) Yijun Gao et al.   Protein & Cell

East meets West: ethnic differences in epidemiology and clinical behaviors of lung cancer between East Asians and Caucasians

(2011) Wei Zhou et al.   Chinese Journal of Cancer

Identifying cancer driver genes in tumor genome sequencing studies

(2010) Ahrim Youn et al.   BIOINFORMATICS

Driver mutations and differential sensitivity to targeted therapies: a new approach to the treatment of lung adenocarcinoma

(2010) Giuseppe Bronte et al.   CANCER TREATMENT REVIEWS

Genetic profiling and epidermal growth factor receptor-directed therapy in nonsmall cell lung cancer

(2010) J. Cadranel et al.   EUROPEAN RESPIRATORY JOURNAL

Lung Adenocarcinoma From East Asian Never-Smokers Is a Disease Largely Defined by Targetable Oncogenic Mutant Kinases

(2010) Yihua Sun et al.   JOURNAL OF CLINICAL ONCOLOGY

KRAS and BRAF: drug targets and predictive biomarkers

(2010) Efsevia Vakiani et al.   JOURNAL OF PATHOLOGY

Frequency of EGFR and KRAS Mutations in Japanese Patients with Lung Adenocarcinoma with Features of the Mucinous Subtype of Bronchioloalveolar Carcinoma

(2010) Akito Hata et al.   Journal of Thoracic Oncology

Fusion of EML4 and ALK is associated with development of lung adenocarcinomas lacking EGFR and KRAS mutations and is correlated with ALK expression

(2010) Xuchao Zhang et al.   Molecular Cancer

Rapidly Acquired Resistance to EGFR Tyrosine Kinase Inhibitors in NSCLC Cell Lines through De-Repression of FGFR2 and FGFR3 Expression

(2010) Kathryn E. Ware et al.   PLoS One

Clinicopathologic Features of Non-Small-Cell Lung Cancer with EML4–ALK Fusion Gene

(2009) Tsuyoshi Takahashi et al.   ANNALS OF SURGICAL ONCOLOGY

Histologic Considerations for Individualized Systemic Therapy Approaches for the Management of Non-small Cell Lung Cancer

(2009) Howard West et al.   CHEST

Nonsmall cell lung cancer in never smokers

(2009) Giorgio V Scagliotti et al.   CURRENT OPINION IN ONCOLOGY

Advances in Target Therapy for Lung Cancer

(2009) T. Mitsudomi   JAPANESE JOURNAL OF CLINICAL ONCOLOGY

Clinical outcome of patients with non-small cell lung cancer receiving front-line chemotherapy according to EGFR and K-RAS mutation status

(2009) Aristea Kalikaki et al.   LUNG CANCER

KRAS mutations and resistance to EGFR-TKIs treatment in patients with non-small cell lung cancer: A meta-analysis of 22 studies

(2009) Chen Mao et al.   LUNG CANCER

Are RAS mutations predictive markers of resistance to standard chemotherapy?

(2009) Yohann Loriot et al.   Nature Reviews Clinical Oncology

Gefitinib or Carboplatin–Paclitaxel in Pulmonary Adenocarcinoma

(2009) Tony S. Mok et al.   NEW ENGLAND JOURNAL OF MEDICINE

Clinicopathologic and Molecular Features of Epidermal Growth Factor Receptor T790M Mutation and c-MET Amplification in Tyrosine Kinase Inhibitor-resistant Chinese Non-small Cell Lung Cancer

(2009) Hua-Jun Chen et al.   PATHOLOGY & ONCOLOGY RESEARCH

High-Resolution Melting Analysis for Rapid Detection ofKRAS, BRAF,andPIK3CAGene Mutations in Colorectal Cancer

(2008) Lisa Simi et al.   AMERICAN JOURNAL OF CLINICAL PATHOLOGY

EML4-ALK Fusion Is Linked to Histological Characteristics in a Subset of Lung Cancers

(2008) Kentaro Inamura et al.   Journal of Thoracic Oncology