In Silico Assessment of Potential Druggable Pockets on the Surface of α1-Antitrypsin Conformers
出版年份 2012 全文链接
标题
In Silico Assessment of Potential Druggable Pockets on the Surface of α1-Antitrypsin Conformers
作者
关键词
-
出版物
PLoS One
Volume 7, Issue 5, Pages e36612
出版商
Public Library of Science (PLoS)
发表日期
2012-05-09
DOI
10.1371/journal.pone.0036612
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Visualisation of variable binding pockets on protein surfaces by probabilistic analysis of related structure sets
- (2012) Paul Ashford et al. BMC BIOINFORMATICS
- Analysis of surface cavity in serpin family reveals potential binding sites for chemical chaperone to reduce polymerization
- (2011) Poonam Singh et al. JOURNAL OF MOLECULAR MODELING
- Systematic Exploitation of Multiple Receptor Conformations for Virtual Ligand Screening
- (2011) Giovanni Bottegoni et al. PLoS One
- Detection of protein-protein interactions using nonimmune IgG and BirA-mediated biotinylation
- (2010) Cai Huang et al. BIOTECHNIQUES
- Druggable pockets and binding site centric chemical space: a paradigm shift in drug discovery
- (2010) Stéphanie Pérot et al. DRUG DISCOVERY TODAY
- Drug-like Density: A Method of Quantifying the “Bindability” of a Protein Target Based on a Very Large Set of Pockets and Drug-like Ligands from the Protein Data Bank
- (2010) Robert P. Sheridan et al. Journal of Chemical Information and Modeling
- Understanding and Predicting Druggability. A High-Throughput Method for Detection of Drug Binding Sites
- (2010) Peter Schmidtke et al. JOURNAL OF MEDICINAL CHEMISTRY
- fpocket: online tools for protein ensemble pocket detection and tracking
- (2010) P. Schmidtke et al. NUCLEIC ACIDS RESEARCH
- PROSESS: a protein structure evaluation suite and server
- (2010) M. Berjanskii et al. NUCLEIC ACIDS RESEARCH
- Folding and binding cascades: Dynamic landscapes and population shifts
- (2010) Sandeep Kumar et al. PROTEIN SCIENCE
- Conformational Pathology of the Serpins: Themes, Variations, and Therapeutic Strategies
- (2009) Bibek Gooptu et al. Annual Review of Biochemistry
- Identifying and Characterizing Binding Sites and Assessing Druggability
- (2009) Thomas A. Halgren Journal of Chemical Information and Modeling
- Molecular docking and ligand specificity in fragment-based inhibitor discovery
- (2009) Yu Chen et al. Nature Chemical Biology
- A Quantitative Model of Thermal Stabilization and Destabilization of Proteins by Ligands
- (2008) Piotras Cimmperman et al. BIOPHYSICAL JOURNAL
- What induces pocket openings on protein surface patches involved in protein–protein interactions?
- (2008) Susanne Eyrisch et al. JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN
- Polymers and inflammation: disease mechanisms of the serpinopathies
- (2008) Bibek Gooptu et al. JOURNAL OF EXPERIMENTAL MEDICINE
- PDBsum new things
- (2008) R. A. Laskowski NUCLEIC ACIDS RESEARCH
- Preventing serpin aggregation: The molecular mechanism of citrate action upon antitrypsin unfolding
- (2008) Mary C. Pearce et al. PROTEIN SCIENCE
- Multiple diverse ligands binding at a single protein site: A matter of pre-existing populations
- (2002) Buyong Ma et al. PROTEIN SCIENCE
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