Identification of Thioredoxin Glutathione Reductase Inhibitors That Kill Cestode and Trematode Parasites

Investigations of the Catalytic Mechanism of Thioredoxin Glutathione Reductase fromSchistosoma mansoni

(2011) Hsin-Hung Huang et al.   BIOCHEMISTRY

A recombinant thioredoxin-glutathione reductase from Fasciola hepatica induces a protective response in rabbits

(2011) Gabriela Maggioli et al.   EXPERIMENTAL PARASITOLOGY

Hysteresis in thioredoxin-glutathione reductase (TGR) from the adult stage of the liver fluke Fasciola hepatica

(2011) Alberto Guevara-Flores et al.   PARASITOLOGY INTERNATIONAL

Thioredoxin and glutathione systems differ in parasitic and free-living platyhelminths

(2010) Lucía Otero et al.   BMC GENOMICS

Clinical features and treatment of alveolar echinococcosis

(2010) Peter Kern   CURRENT OPINION IN INFECTIOUS DISEASES

In vitro killing action of auranofin on Taenia crassiceps metacestode (cysticerci) and inactivation of thioredoxin–glutathione reductase (TGR)

(2010) José J. Martínez-González et al.   PARASITOLOGY RESEARCH

Structure Mechanism Insights and the Role of Nitric Oxide Donation Guide the Development of Oxadiazole-2-Oxides as Therapeutic Agents against Schistosomiasis

(2009) Ganesha Rai et al.   JOURNAL OF MEDICINAL CHEMISTRY

Synthesis of oxadiazole-2-oxide analogues as potential antischistosomal agents

(2009) Ganesha Rai et al.   TETRAHEDRON LETTERS

Advancing Drug Innovation for Neglected Diseases—Criteria for Lead Progression

(2009) Solomon Nwaka et al.   PLoS Neglected Tropical Diseases

Platyhelminth Mitochondrial and Cytosolic Redox Homeostasis Is Controlled by a Single Thioredoxin Glutathione Reductase and Dependent on Selenium and Glutathione

(2008) Mariana Bonilla et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Helminth infections: the great neglected tropical diseases

(2008) Peter J. Hotez et al.   JOURNAL OF CLINICAL INVESTIGATION

Identification of oxadiazoles as new drug leads for the control of schistosomiasis

(2008) Ahmed A Sayed et al.   NATURE MEDICINE

Will new antischistosomal drugs finally emerge?

(2008) Donato Cioli et al.   TRENDS IN PARASITOLOGY

Quantitative High-Throughput Screen Identifies Inhibitors of the Schistosoma mansoni Redox Cascade

(2008) Anton Simeonov et al.   PLoS Neglected Tropical Diseases