Article
Multidisciplinary Sciences
Bruce Anderson, John Pannell, Sylvain Billiard, Concetta Burgarella, Hugo de Boer, Mathilde Dufay, Andrew J. Helmstetter, Marcos Mendez, Sarah P. Otto, Denis Roze, Herve Sauquet, Daniel Schoen, Jurg Schonenberger, Mario Vallejo-Marin, Rosana Zenil-Ferguson, Jos Kafer, Sylvain Glemin
Summary: Species diversity can vary greatly due to differences in speciation and extinction rates. This study examines the effects of various plant traits on diversification and finds that most traits have conflicting impacts. The complexities of trait-diversification relationships and context dependence highlight the need for controlled approaches in correlational studies.
Article
Clinical Neurology
Elzbieta A. Bajcar, Wojciech Swedziol, Krzysztof Wrzesniewski, Jan Blecharz, Przemyslaw Babel
Summary: The cognitive factors, such as expectancy of pain intensity and desire for pain relief, can influence the memory of pain induced by running, but do not affect the memory of pain unpleasantness.
JOURNAL OF PAIN RESEARCH
(2022)
Article
Multidisciplinary Sciences
Bruce Anderson, John Pannell, Sylvain Billiard, Concetta Burgarella, Hugo de Boer, Mathilde Dufay, Andrew J. Helmstetter, Marcos Mendez, Sarah P. Otto, Denis Roze, Herve Sauquet, Daniel Scheon, Jurg Schoenenbereger, Mario Vallejo-Marin, Rosana Zenil-Fergusion, Jos Kafer, Sylvain Glemin
Summary: Species diversity can vary greatly across lineages due to differences in speciation and extinction rates. This study examines the effects of various plant traits on diversification and finds that most traits have contrasting effects. The complexity of pathways linking traits to diversification suggests that interpreting their correlations may be challenging, and the context dependence means that the effects of specific traits on diversification may differ across lineages and timescales. This calls for taxonomically and context-controlled approaches in studying trait-diversification relationships.
Article
Microbiology
Daniel Poston, Yiska Weisblum, Alvaro Hobbs, Paul D. Bieniasz
Summary: These data identify a host pathway by which VPS29 and associated factors control the endosomal environment and influence susceptibility to viral infection. This pathway could serve as a pharmaceutical target for intervention in zoonotic viral diseases, including those caused by coronaviruses, influenza viruses, and filoviruses, all of which are pandemic threats.
Article
Computer Science, Information Systems
Ulrich Gnewuch, Stefan Morana, Marc T. P. Adam, Alexander Maedche
Summary: Research has shown that using social cues in chatbot design enhances users' social presence and usage intentions. However, the effect of chatbot response time on social cues is still unclear. This study examines the role of users' prior experience with chatbots and finds that delayed response time has opposing effects on social presence and usage intentions, highlighting the differences between experienced and novice users.
BUSINESS & INFORMATION SYSTEMS ENGINEERING
(2022)
Article
Anesthesiology
Jonathan N. Davies, Louise Sharpe, Melissa A. Day, Ben Colagiuri
Summary: Recent studies suggest that placebo effects contribute to acute pain relief after mindfulness interventions. However, the specific effects of mindfulness processes and their interaction with placebo effects are still unclear. This study aimed to examine the role of mindfulness and placebo processes in mindfulness-based pain attenuation.
Article
Biochemistry & Molecular Biology
Lisa U. Teufel, Mihai G. Netea, Frank L. Van de Veerdonk, Charles A. Dinarello, Leo A. B. Joosten, Rob J. W. Arts
Summary: Trained immunity is the long-term functional reprogramming of innate immune cells after exposure to pathogens, vaccines, or their ligands. It is mediated through epigenetic and metabolic mechanisms and can also be induced by endogenous compounds and cytokines.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Biology
Lauren Y. Atlas, Troy C. Dildine, Esther E. Palacios-Barrios, Qingbao Yu, Richard C. Reynolds, Lauren A. Banker, Shara S. Grant, Daniel S. Pine
Summary: Recent data suggest that interactions between systems involved in higher order knowledge and associative learning drive responses during value-based learning. These systems dynamically modulate pain perception and influence pain and heat-evoked brain responses. Imaging data also identify three types of neural networks involved in pain generation and value-based learning.
Article
Behavioral Sciences
Julian C. Motzkin, Jaryd Hiser, Ian Carroll, Richard Wolf, Mustafa K. Baskaya, Michael Koenigs, Lauren Y. Atlas
Summary: Pain is strongly influenced by expectations and beliefs. The ventromedial prefrontal cortex (VMPFC) plays a role in pain processing, predictions, and learning. Damage to the VMPFC enhances the effect of expectations on pain processing, specifically impairing the integration of new sensory feedback to update expectations about pain.
Article
Business
Xingyuan Wang, Yun Liu, Shuyang Wang, Haipeng (Allan) Chen
Summary: This study explores the interaction between firm's new product preannouncement (NPP) strategies and consumers' regulatory foci on their WOM intention, and identifies the underlying mechanisms and moderating variables. The findings provide valuable insights for firms to develop effective NPP strategies.
JOURNAL OF RETAILING AND CONSUMER SERVICES
(2022)
Article
Multidisciplinary Sciences
Corey M. Ziemba, Eero P. Simoncelli
Summary: The study demonstrates the opposing perceptual implications of the tradeoff between selectivity and invariance in sensory processing through specialized stimuli and two complementary discrimination tasks. The results show that ideal observers improve discrimination performance with stimulus size, while humans show improved family discrimination but worsened sample discrimination.
NATURE COMMUNICATIONS
(2021)
Article
Environmental Studies
Jesse L. Preston, Faith Shin
Summary: This study investigates the opposing influences of religion on environmentalism through individual differences in Religious Fundamentalism and Spirituality. The findings show that Spirituality has a positive effect on environmental attitudes, while Religious Fundamentalism has a negative effect. The positive effects of Spirituality on environmental attitudes are partly mediated by trait compassion and moral foundations, while the negative effects of Fundamentalism are partly explained by Right-Wing Authoritarianism. Overall, the combined effects of Spirituality and Fundamentalism are better predictors of environmental concerns, even when controlling for political attitudes.
JOURNAL OF ENVIRONMENTAL PSYCHOLOGY
(2022)
Article
Biochemistry & Molecular Biology
Giada Amodeo, Benedetta Verduci, Patrizia Sartori, Patrizia Procacci, Vincenzo Conte, Gianfranco Balboni, Paola Sacerdote, Silvia Franchi
Summary: The study indicates that mice treated with the proteasome inhibitor bortezomib may develop anxiety and depression, which are related to neuroinflammation and prokineticin system activation. Treatment with the prokineticin system antagonist PC1, which has anti-pain and anti-neuroinflammation effects, can prevent mood alterations.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Neurosciences
Jakub Mlost, Przemyslaw Kac, Marta Kedziora, Katarzyna Starowicz
Summary: This study demonstrates the anti-nociceptive and chondroprotective potential of beta-Caryophyllene (BCP) in an animal model of osteoarthritis (OA). BCP acts as a natural agonist of CB2 and does not produce tolerance for analgesic effects. These findings suggest that BCP could be a novel therapeutic strategy for treating OA.
Review
Neurosciences
Rabia Bouali-Benazzouz, Marc Landry, Abdelhamid Benazzouz, Pascal Fossat
Summary: Animal models play a crucial role in studying neuropathic pain, but objective assessment of pain and validating pain phenotypes present challenges. Utilizing various behavioral approaches to investigate and validate pain phenotypes can help uncover novel pain mechanisms.
PROGRESS IN NEUROBIOLOGY
(2021)
Letter
Anesthesiology
Siri Leknes, Lauren Y. Atlas
BRITISH JOURNAL OF ANAESTHESIA
(2020)
Article
Neurosciences
Weihao Zheng, Choong-Wan Woo, Zhijun Yao, Pavel Goldstein, Lauren Y. Atlas, Mathieu Roy, Liane Schmidt, Anjali Krishnan, Marieke Jepma, Bin Hu, Tor D. Wager
Article
Neurosciences
In-Seon Lee, Elizabeth A. Necka, Lauren Y. Atlas
Article
Psychology, Biological
Dobromir Rahnev, Kobe Desender, Alan L. F. Lee, William T. Adler, David Aguilar-Lleyda, Basak Akdogan, Polina Arbuzova, Lauren Y. Atlas, Fuat Balci, Ji Won Bang, Indrit Begue, Damian P. Birney, Timothy F. Brady, Joshua Calder-Travis, Andrey Chetverikov, Torin K. Clark, Karen Davranche, Rachel N. Denison, Troy C. Dildine, Kit S. Double, Yalcin A. Duyan, Nathan Faivre, Kaitlyn Fallow, Elisa Filevich, Thibault Gajdos, Regan M. Gallagher, Vincent de Gardelle, Sabina Gherman, Nadia Haddara, Marine Hainguerlot, Tzu-Yu Hsu, Xiao Hu, Inaki Iturrate, Matt Jaquiery, Justin Kantner, Marcin Koculak, Mahiko Konishi, Christina Koss, Peter D. Kvam, Sze Chai Kwok, Mael Lebreton, Karolina M. Lempert, Chien Ming Lo, Liang Luo, Brian Maniscalco, Antonio Martin, Sebastien Massoni, Julian Matthews, Audrey Mazancieux, Daniel M. Merfeld, Denis O'Hora, Eleanor R. Palser, Boryslaw Paulewicz, Michael Pereira, Caroline Peters, Marios G. Philiastides, Gerit Pfuhl, Fernanda Prieto, Manuel Rausch, Samuel Recht, Gabriel Reyes, Marion Rouault, Jerome Sackur, Saeedeh Sadeghi, Jason Samaha, Tricia X. F. Seow, Medha Shekhar, Maxine T. Sherman, Marta Siedlecka, Zuzanna Skora, Chen Song, David Soto, Sai Sun, Jeroen J. A. van Boxtel, Shuo Wang, Christoph T. Weidemann, Gabriel Weindel, Michal Wierzchon, Xinming Xu, Qun Ye, Jiwon Yeon, Futing Zou, Ariel Zylberberg
NATURE HUMAN BEHAVIOUR
(2020)
Article
Neurosciences
Stephan Geuter, Elizabeth A. Reynolds Losin, Mathieu Roy, Lauren Y. Atlas, Liane Schmidt, Anjali Krishnan, Leonie Koban, Tor D. Wager, Martin A. Lindquist
Article
Multidisciplinary Sciences
Troy C. Dildine, Elizabeth A. Necka, Lauren Y. Atlas
SCIENTIFIC REPORTS
(2020)
Article
Neurosciences
Rany Abend, Mira A. Bajaj, Anita Harrewijn, Chika Matsumoto, Kalina J. Michalska, Elizabeth Necka, Esther E. Palacios-Barrios, Ellen Leibenluft, Lauren Y. Atlas, Daniel S. Pine
Summary: The study investigates pain-anticipatory psychophysiological response in youth with anxiety and healthy youth using thermal stimulation. The results show that youth with anxiety exhibit enhanced psychophysiological response during the anticipation of painful stimulation, and this response is correlated with specific brain structures. Specifically, thinner dorsolateral prefrontal cortex thickness is associated with stronger anticipatory response, while thicker posterior insula thickness is associated with stronger response to thermal stimulation.
JOURNAL OF PSYCHIATRY & NEUROSCIENCE
(2021)
Review
Behavioral Sciences
Lauren Y. Atlas
Summary: Pain is a fundamental experience that promotes survival, standing at the intersection of multiple health crises for humans. The study of placebo analgesia reveals how social, cognitive, and affective processes directly shape pain, offering potential paths for mitigating these crises. Collaborations between clinicians and social and affective scientists can address outstanding questions and leverage the placebo effect to reduce pain and improve human health.
TRENDS IN COGNITIVE SCIENCES
(2021)
Article
Public, Environmental & Occupational Health
Elizabeth A. Necka, Carolyn Amir, Troy C. Dildine, Lauren Y. Atlas
Summary: Results from five online studies suggest that participants tend to choose healthcare providers who appear more competent based on facial visual information alone. The perceived competence of providers also predicts participants' expectations about post-procedural pain and medication use. Additionally, participants' perception of similarity to providers influences expectations about pain and treatment outcomes.
SOCIAL SCIENCE & MEDICINE
(2021)
Article
Clinical Neurology
Carolyn Amir, Margaret Rose-McCandlish, Rachel Weger, Troy C. Dildine, Dominik Mischkowski, Elizabeth A. Necka, In-seon Lee, Tor D. Wager, Daniel S. Pine, Lauren Y. Atlas
Summary: This study found that pain threshold and tolerance are moderately reliable, while the correlation between pain rating and stimulus temperature has low reliability. Female participants showed higher reliability in pain sensitivity measures compared to male participants.
Article
Neurosciences
Xiaochun Han, Yoni K. Ashar, Philip Kragel, Bogdan Petre, Victoria Schelkun, Lauren Y. Atlas, Luke J. Chang, Marieke Jepma, Leonie Koban, Elizabeth A. Reynolds Losin, Mathieu Roy, Choong-Wan Woo, Tor D. Wager
Summary: The NPS has shown large effect sizes in predicting pain reports within individuals and medium effect sizes in predicting individual differences. It exhibits excellent short-term test-retest reliability, with reliability scaling with the number of trials. The NPS is not a substitute for individual differences in pain reports but can serve as a reliable measure of pain-related physiology.
Article
Psychology, Biological
Lauren Y. Atlas, Christina A. Sandman, Elizabeth A. Phelps
Summary: The study tested the impact of rating expectations on arousal during classical conditioning, finding that participants who provided online expectancy ratings showed slower learning speed, reduced reversal of SCR, and the effects of subjective expectancy on SCR could be fully explained within the rating group.
Article
Neurosciences
Rany Abend, Sonia G. Ruiz, Mira A. Bajaj, Anita Harrewijn, Julia O. Linke, Lauren Y. Atlas, Anderson M. Winkler, Daniel S. Pine
Summary: This study explores the pathological mechanisms of anxiety disorders and finds that patients with anxiety disorders exhibit excessive physiological responses to threats, which are related to intrinsic connectivity within specific brain circuits.
NEUROBIOLOGY OF STRESS
(2022)
Article
Psychiatry
Dominik Mischkowski, Caitlin M. Stavish, Esther E. Palacios-Barrios, Lauren A. Banker, Troy C. Dildine, Lauren Y. Atlas
Summary: The study found that dispositional mindfulness only mitigated acute thermal pain when assessed using the MPQ, and was not associated with experimental thermal pain assessments. These findings may reflect differences in evaluation methods or the type of pain assessed.
PSYCHOSOMATIC MEDICINE
(2021)
Letter
Psychiatry
Andrea W. M. Evers, Luana Colloca, Charlotte Blease, Jens Gaab, Karin B. Jensen, Lauren Y. Atlas, Chris J. Beedie, Fabrizio Benedetti, Ulrike Bingel, Christian Buchel, Jet Bussemaker, Ben Colagiuri, Alia J. Crum, Damien G. Finniss, Andrew L. Geers, Jeremy Howick, Regine Klinger, Stefanie Helena Meeuwis, Karin Meissner, Vitaly Napadow, Keith J. Petrie, Winfried Rief, Ionica Smeets, Tor D. Wager, Vishvarani Wanigasekera, Lene Vase, John M. Kelley, Irving Kirsch
PSYCHOTHERAPY AND PSYCHOSOMATICS
(2021)