Inflammation-Driven Reprogramming of CD4+Foxp3+ Regulatory T Cells into Pathogenic Th1/Th17 T Effectors Is Abrogated by mTOR Inhibition in vivo

Impact of Protective IL-2 Allelic Variants on CD4+Foxp3+ Regulatory T Cell Function In Situ and Resistance to Autoimmune Diabetes in NOD Mice

(2014) E. Sgouroudis et al.   JOURNAL OF IMMUNOLOGY

Control of TH17 cells occurs in the small intestine

(2011) Enric Esplugues et al.   NATURE

Stability of the Regulatory T Cell Lineage in Vivo

(2010) Y. P. Rubtsov et al.   SCIENCE

Keratinocytes Determine Th1 Immunity during Early Experimental Leishmaniasis

(2010) Jan M. Ehrchen et al.   PLoS Pathogens

Leishmania-Induced Inactivation of the Macrophage Transcription Factor AP-1 Is Mediated by the Parasite Metalloprotease GP63

(2010) Irazú Contreras et al.   PLoS Pathogens

IL-17-producing human peripheral regulatory T cells retain suppressive function

(2009) G. Beriou et al.   BLOOD

The IL-6-deficient mouse exhibits impaired lymphocytic responses to a vaccine combining live Leishmania major and CpG oligodeoxynucleotides

(2009) Wenhui Wu et al.   CANADIAN JOURNAL OF MICROBIOLOGY

Natural Treg cells spontaneously differentiate into pathogenic helper cells in lymphopenic conditions

(2009) João H. Duarte et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

The mTOR Kinase Differentially Regulates Effector and Regulatory T Cell Lineage Commitment

(2009) Greg M. Delgoffe et al.   IMMUNITY

Instability of the transcription factor Foxp3 leads to the generation of pathogenic memory T cells in vivo

(2009) Xuyu Zhou et al.   NATURE IMMUNOLOGY

Foxp3+ regulatory T cells: differentiation, specification, subphenotypes

(2009) Markus Feuerer et al.   NATURE IMMUNOLOGY

Interleukin 10 acts on regulatory T cells to maintain expression of the transcription factor Foxp3 and suppressive function in mice with colitis

(2009) Masako Murai et al.   NATURE IMMUNOLOGY

FOXP3 Forkhead Domain Mutation and Regulatory T Cells in the IPEX Syndrome

(2009) Eva d'Hennezel et al.   NEW ENGLAND JOURNAL OF MEDICINE

Differential Responses of Human Regulatory T Cells (Treg) and Effector T Cells to Rapamycin

(2009) Laura Strauss et al.   PLoS One

Heterogeneity of natural Foxp3+T cells: A committed regulatory T-cell lineage and an uncommitted minor population retaining plasticity

(2009) Noriko Komatsu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Preferential Generation of Follicular B Helper T Cells from Foxp3+ T Cells in Gut Peyer's Patches

(2009) M. Tsuji et al.   SCIENCE

CD4+Foxp3+ regulatory T cells in the control of autoimmunity: in vivo veritas

(2008) Ciriaco A Piccirillo et al.   CURRENT OPINION IN IMMUNOLOGY

DNA methylation controls Foxp3 gene expression

(2008) Julia K. Polansky et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Central Role of Defective Interleukin-2 Production in the Triggering of Islet Autoimmune Destruction

(2008) Qizhi Tang et al.   IMMUNITY

Molecular Antagonism and Plasticity of Regulatory and Inflammatory T Cell Programs

(2008) Xuexian O. Yang et al.   IMMUNITY

The AKT–mTOR axis regulates de novo differentiation of CD4+Foxp3+cells

(2008) Sokol Haxhinasto et al.   JOURNAL OF EXPERIMENTAL MEDICINE

TGF-β-induced Foxp3 inhibits TH17 cell differentiation by antagonizing RORγt function

(2008) Liang Zhou et al.   NATURE

T cell receptor signaling controls Foxp3 expression via PI3K, Akt, and mTOR

(2008) S. Sauer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Natural and TGF-β–induced Foxp3+CD4+ CD25+ regulatory T cells are not mirror images of each other

(2008) David A. Horwitz et al.   TRENDS IN IMMUNOLOGY

The Biology of Interleukin-2

(2007) Thomas R. Malek   Annual Review of Immunology

Generation of Potent and Stable Human CD4+ T Regulatory Cells by Activation-independent Expression of FOXP3

(2007) Sarah E Allan et al.   MOLECULAR THERAPY