Withanolides-Induced Breast Cancer Cell Death Is Correlated with Their Ability to Inhibit Heat Protein 90

Natural withanolides: an overview

(2011) Li-Xia Chen et al.   NATURAL PRODUCT REPORTS

17-DMAG targets the nuclear factor- B family of proteins to induce apoptosis in chronic lymphocytic leukemia: clinical implications of HSP90 inhibition

(2010) E. Hertlein et al.   BLOOD

4β-Hydroxywithanolide E from Physalis peruviana (golden berry) inhibits growth of human lung cancer cells through DNA damage, apoptosis and G2/M arrest

(2010) Ching-Yu Yen et al.   BMC CANCER

Protoapigenone, a natural derivative of apigenin, induces mitogen-activated protein kinase-dependent apoptosis in human breast cancer cells associated with induction of oxidative stress and inhibition of glutathione S-transferase π

(2010) Wen-Ying Chen et al.   INVESTIGATIONAL NEW DRUGS

Withaferin A targets heat shock protein 90 in pancreatic cancer cells

(2009) Yanke Yu et al.   BIOCHEMICAL PHARMACOLOGY

NF-κB and cancer: how intimate is this relationship

(2009) Sahdeo Prasad et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Steroidal Lactones from Withania somnifera, an Ancient Plant for Novel Medicine

(2009) Mohammad Mirjalili et al.   MOLECULES

Cell proliferation regulated by estradiol receptor: Therapeutic implications

(2009) Gabriella Castoria et al.   STEROIDS

Dual Targeting of HSC70 and HSP72 Inhibits HSP90 Function and Induces Tumor-Specific Apoptosis

(2008) Marissa V. Powers et al.   CANCER CELL

Tubocapsanolide A Inhibits Transforming Growth Factor-β-activating Kinase 1 to Suppress NF-κB-induced CCR7

(2008) Mei-Ren Pan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Tubocapsenolide A, a Novel Withanolide, Inhibits Proliferation and Induces Apoptosis in MDA-MB-231 Cells by Thiol Oxidation of Heat Shock Proteins

(2008) Wen-Ying Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Dicoumarol down-regulates human PTTG1/Securin mRNA expression through inhibition of Hsp90

(2008) A. Hernandez et al.   MOLECULAR CANCER THERAPEUTICS