Article
Nursing
Angela Starkweather, Kathryn Ward, Bright Eze, Ahleah Gavin, Cynthia L. Renn, Susan G. Dorsey
Summary: This study aims to identify neurological and transcriptomic biomarkers predictive of chronic low back pain and will follow 340 individuals with acute low back pain and 40 healthy controls over a period of two years. The results will compare the neurophysiological and transcriptomic profiles of healthy controls and individuals with acute low back pain.
RESEARCH IN NURSING & HEALTH
(2022)
Article
Orthopedics
Flavia Cordeiro Medeiros, Luciola da Cunha Menezes Costa, Leonardo Oliveira Pena Costa, Indiara Soares Oliveira, Tatiane da Silva
Summary: In a cohort of low back pain patients presenting to emergency departments in Sao Paulo, Brazil, nearly 40% experienced a recurrence within 1 year after recovering from acute low back pain. The risk of recurrence varied depending on the classification used in the SBST. Age, perceived risk of persistent low back pain, and disability were identified as prognostic factors for recurrence.
JOURNAL OF ORTHOPAEDIC & SPORTS PHYSICAL THERAPY
(2022)
Article
Public, Environmental & Occupational Health
C. Blumenberg, F. C. Wehrmeister, F. C. Barros, B. D. Flesch, F. Guimaraes, I Valerio, L. Z. Ferreira, M. Echeverria, S. A. Karam, H. Goncalves, A. M. B. Menezes
Summary: The study found that excessive use of mobile devices is associated with neck and low back pains, while excessive use of computers is only associated with neck pain. Therefore, guidelines should be developed to recommend the appropriate length of time for using computers and mobile devices to prevent back pain.
Article
Rheumatology
John G. Hanly, Caroline Gordon, Sang-Cheol Bae, Juanita Romero-Diaz, Jorge Sanchez-Guerrero, Sasha Bernatsky, Ann E. Clarke, Daniel J. Wallace, David A. Isenberg, Anisur Rahman, Joan T. Merrill, Paul R. Fortin, Dafna D. Gladman, Murray B. Urowitz, Ian N. Bruce, Michelle Petri, Ellen M. Ginzler, M. A. Dooley, Rosalind Ramsey-Goldman, Susan Manzi, Andreas Jonsen, Graciela S. Alarcon, Ronald F. Vollenhoven, Cynthia Aranow, Meggan Mackay, Guillermo Ruiz-Irastorza, S. Sam Lim, Murat Inanc, Kenneth C. Kalunian, Soren Jacobsen, Christine A. Peschken, Diane L. Kamen, Anca Askanase, Vernon Farewell
Summary: This large and long-term study on neuropsychiatric events in systemic lupus erythematosus (SLE) identified predictors of occurrence and resolution, showing that the nature and attribution of the events greatly impact their course. Factors such as disease activity, medications, and ethnicity were found to influence the prognosis and resolution of these events in SLE patients.
ARTHRITIS & RHEUMATOLOGY
(2021)
Article
Clinical Neurology
Indiara Soares Oliveira, Tatiane da Silva, Leonardo Oliveira Pena Costa, Flavia Cordeiro Medeiros, Renan Kendy Ananias Oshima, Diego Galace de Freitas, Thiago Yukio Fukuda, Luciola da Cunha Menezes Costa
Summary: This study examined the prognosis of recent-onset low back pain in emergency department patients over a one-year follow-up. Most patients showed some level of recovery within 12 months, with factors such as higher pain levels, perceived risk of persistent pain, reduced activity days, more pain sites, and longer duration of pain associated with complete nonrecovery within 6 months.
Article
Medicine, General & Internal
Jing Tian, Graeme Jones, Xin Lin, Yuan Zhou, Anna King, James Vickers, Feng Pan
Summary: This study investigates the association between the number of chronic pain sites and the risk of dementia and its subtypes. The findings suggest that a greater number of chronic pain sites is associated with an increased risk of all-cause dementia and Alzheimer's disease, but not vascular and frontotemporal dementia.
Article
Rheumatology
Anna Eberhard, Stefan Bergman, Thomas Mandl, Tor Olofsson, Maria Rydholm, Lennart Jacobsson, Carl Turesson
Summary: Pain is a major symptom in patients with rheumatoid arthritis, and this study aimed to investigate the pain course and predictors of unacceptable pain in patients with early RA. Results showed that pain improved significantly in the first 6 months but then remained stable, and over one third of patients had unacceptable pain 5 years later. Lower swollen joint count was associated with unacceptable pain at 5 years, while non-inflammatory long-lasting pain was more common in anti-CCP negative patients.
ARTHRITIS RESEARCH & THERAPY
(2021)
Article
Medicine, General & Internal
Maaike N. Scheffers-Barnhoorn, Miriam L. Haaksma, Wilco P. Achterberg, Arthur H. P. Niggebrugge, Max P. L. van der Sijp, Jolanda C. M. van Haastregt, Monica van Eijk
Summary: This study aimed to examine the course of fear of falling (FoF) up to 1 year after hip fracture and the effect of prefracture FoF on its development. The results showed that the mean score of FES-I was close to the cut-off value of 11 at 6 weeks after fracture, and levels only slightly decreased over time. One year after fracture, almost one-third of the population still had FoF. The study suggests conducting structural assessment of FoF in the first 12 weeks after fracture.
Article
Obstetrics & Gynecology
Teresa Algard, Paul Kalliokoski, Kerstin Ahlqvist, Angela Schlager, Per Kristiansson
Summary: Depressive symptoms in early pregnancy are associated with the development and intensity of pelvic girdle pain in late pregnancy. Screening and treating depressive symptoms in early pregnancy may help reduce and prevent the occurrence of disabling pelvic girdle pain in late pregnancy.
ACTA OBSTETRICIA ET GYNECOLOGICA SCANDINAVICA
(2023)
Article
Clinical Neurology
Richard Kasch, Julia Truthmann, Mark J. Hancock, Christopher G. Maher, Markus Otto, Christopher Nell, Niklas Reichwein, Robin Bulow, Jean-Francois Chenot, Andre Hofer, Georgi Wassilew, Carsten Oliver Schmidt
Summary: This population-based cohort study examined the associations between common lumbar degenerative changes observed on magnetic resonance imaging (MRI) and low back pain (LBP). The study found that there is no clinically important association between these degenerative findings and LBP, with most effects less than one unit on a 0 to 10 pain scale. Longitudinal studies on this topic are limited.
Article
Medicine, General & Internal
David R. Axon, Darlena Le
Summary: This study identified that factors such as age, gender, race, marital status, income level, employment status, number of chronic conditions, physical activity, smoking status, perceived physical health, and geographical region could predict the severity of pain reported by older adults in the US.
Article
Obstetrics & Gynecology
Samantha Benlolo, John G. Hanlon, Lindsay Shirreff, Guylaine Lefebvre, Heinrich Husslein, Eliane M. Shore
Summary: Preoperative use of validated questionnaires can identify patients at risk for PPSP after hysterectomy, allowing for targeted perioperative interventions to mitigate their risk.
JOURNAL OF MINIMALLY INVASIVE GYNECOLOGY
(2021)
Article
Psychiatry
Calvin Diep, Norma Rosenek, Yuelee Khoo, Wiebke Gandhi, Carien M. van Reekum, Arun V. Ravindran, Karim S. Ladha, Benicio N. Frey, Roumen V. Milev, Susan Rotzinger, Raymond W. Lam, Sidney H. Kennedy, Wendy Lou, Tim Salomons, Venkat Bhat
Summary: This study investigated the pain-alleviating effects of escitalopram and adjunctive aripiprazole for patients with comorbid pain and depression. The results showed significant improvements in pain severity and interference for patients receiving escitalopram, regardless of treatment response. However, patients receiving aripiprazole after week 8 did not experience further improvement in pain symptoms. Further research is needed to identify interventions that can effectively treat both pain and depression symptoms.
PSYCHIATRY RESEARCH
(2022)
Article
Dermatology
Keiko Yamada, Yasuko Mori, Renzhe Cui, Yasuhiko Kubota, Hideo Asada, Yoshinobu Okuno, Koichi Yamanishi, Hiroyasu Iso
Summary: The study aimed to identify determinants of the clinical course of herpes zoster and immunological responses, focusing on pain trajectories. A pain survey was provided to 375 patients diagnosed with herpes zoster, and their responses were analyzed. The authors identified two pain trajectories associated with postherpetic neuralgia, one with severe acute pain and the other without severe acute pain. The use of nonsteroidal anti-inflammatory drugs was uniquely associated with postherpetic neuralgia accompanied by severe acute pain.
JOURNAL OF DERMATOLOGY
(2023)
Article
Rehabilitation
Angela Vratsistas-Curto, Catherine Sherrington, Annie McCluskey
Summary: The study found that stroke survivors completed a low amount of arm practice during inpatient rehabilitation, with daily practice sessions not meeting clinical guidelines. Factors predicting practice dose included age and cognitive impairment.
DISABILITY AND REHABILITATION
(2021)
Article
Clinical Neurology
Katie A. Butera, Steven Z. George, Trevor A. Lentz
Article
Emergency Medicine
Joshua Ring, Sarah Peskoe, Congwen Zhao, Benjamin W. Friedman, Steven Z. George, Stephanie A. Eucker
ACADEMIC EMERGENCY MEDICINE
(2020)
Article
Orthopedics
Jason M. Beneciuk, Steven Z. George
Summary: This study aimed to determine if an empirically derived subgrouping approach based on physical impairment measures improves information provided by the STarT Back Tool (SBT) for low back pain (LBP) patients receiving physical therapy. Two physical impairment-based subgroups were identified, with a weak, positive relationship observed between baseline SBT risk and impairment subgroups. The physical impairment subgroups were found to improve the prediction of 4-week LBP disability outcomes, but not pain intensity scores.
Article
Anesthesiology
Steven Z. George, Cynthia J. Coffman, Kelli D. Allen, Trevor A. Lentz, Ashley Choate, Adam P. Goode, Corey B. Simon, Janet M. Grubber, Heather King, Chad E. Cook, Francis J. Keefe, Lindsay A. Ballengee, Jennifer Naylor, Joseph Leo Brothers, Catherine Stanwyck, Aviel Alkon, Susan N. Hastings
Article
Anesthesiology
Steven Z. George, Anna Giczewska, Brooke Alhanti, Adam D. Lutz, Ellen Shanley, Charles A. Thigpen, Nrupen A. Bhavsar
Summary: This study aimed to characterize patterns of recurrent physical therapy seeking for musculoskeletal pain conditions and develop a preliminary prediction model to identify those at increased risk of recurrent care seeking. Predictors of increased risk included receiving workers' compensation and Medicare insurance, having comorbid arthritis, being postoperative, age range of 44-64 years, and reporting night sweats or night pain. Predictors of decreased risk included lumbar pain, chronic injury, neck pain, pregnancy, age range of 25-44 years, and smoking.
Article
Clinical Neurology
Steven Z. George, Michael P. Bolognesi, Nrupen A. Bhavsar, Colin T. Penrose, Maggie E. Horn
Summary: This study found that high impact and bothersome chronic pain are common after joint arthroplasty. Non-white race and knee arthroplasty were associated with both chronic pain outcomes.
Article
Orthopedics
Jay M. Levin, Rafeal Baker, Daniel E. Goltz, John Wickman, Trevor A. Lentz, Chad Cook, Steven Z. George, Christopher S. Klifto, Oke A. Anakwenze
Summary: This study investigated the prevalence of different subtypes of psychological distress among shoulder pain patients, evaluated the associations between psychological distress and shoulder pain, disability, and function, and found that operative patients had a higher risk of psychological distress.
JOURNAL OF SHOULDER AND ELBOW SURGERY
(2022)
Article
Anesthesiology
Jason M. Beneciuk, Steven Z. George, Charity G. Patterson, Clair N. Smith, Gerard P. Brennan, Stephen T. Wegener, Eric J. Roseen, Robert B. Saper, Anthony Delitto
Summary: Treatment effect modifiers were identified for disability in patients with acute low back pain, including smoking and pain medication usage. Smokers showed a significant effect of psychologically informed physical therapy (PIPT) compared to usual care, while nonsmokers did not. Participants prescribed >= 3 pain medications also showed a significant effect of PIPT compared to usual care. These findings can inform the design of future clinical trials investigating the effectiveness of tailored PIPT applications.
Article
Anesthesiology
Steven Z. George, Mark D. Bishop, Samuel S. Wu, Roland Staud, Paul A. Borsa, Margaret R. Wallace, Warren. H. Greenfield, Yunfeng Dai, Roger B. Fillingim
Summary: In this clinical trial, interventions matched to the characteristics of a high-risk subgroup defined by specific COMT genotype and pain catastrophizing were tested for their efficacy in exercise-induced muscle injury and pain. The results indicate that these treatments were not effective for the high-risk subgroup in shoulder pain induced by exercise-induced muscle injury. Hence, this phenotype should only be used for prognostic purposes until further trials are completed in clinical populations.
Article
Anesthesiology
Chad E. Cook, Steven Z. George, Trevor Lentz, Christine Park, Christopher Shaffrey, C. Rory Goodwin, Khoi D. Than, Oren N. Gottfried
Summary: This study explored the prevalence, transition types, and outcomes of high-impact chronic pain (HICP) in lumbar spine surgery recipients. It found that HICP decreased after surgery and that transition to and maintenance of HICP status were predicted by biological, psychological, and social factors.
Article
Orthopedics
Steven Z. George, Dana Rubenstein, Michael P. Bolognesi, Maggie E. Horn
Summary: This study analyzed the accuracy of Patient-Reported Outcome Measurement Information System (PROMIS) in assessing high impact chronic pain (HICP) status following total joint arthroplasty (TJA). The results showed that pain interference and sleep disturbance, two PROMIS measures, can be used to estimate HICP status, thereby improving the assessment of TJA outcomes.
JOURNAL OF ARTHROPLASTY
(2023)
Article
Orthopedics
A. P. Goode, R. J. Cleveland, V. B. Kraus, K. A. Taylor, S. Z. George, T. A. Schwartz, J. Renner, J. L. Huebner, J. M. Jordan, Y. M. Golightly
Summary: This study investigates the association between baseline biomarkers and longitudinal changes in disc space narrowing, vertebral osteophytes, and low back pain. The findings suggest that markers of inflammation and perceived pressure pain sensitivity are associated with the longitudinal worsening of low back pain.
OSTEOARTHRITIS AND CARTILAGE
(2023)
Editorial Material
Anesthesiology
Steven Z. George
Article
Orthopedics
Fernando Augusto Goncalves Tavares, Joao Vitor Alves Rossister, Gabriela Caroline Leandro Lima, Leticia Gomes de Oliveira, Witor Souza Cavalcante, Mariana Arias Avila, Steven Zachary George, Thais Cristina Chaves
Summary: Combining pain neuroscience education (PNE) with spinal manipulative therapy (SMT) may result in longer-lasting effects in patients with chronic low back pain (CLBP), possibly mediated by pain self-efficacy. However, in the short term, PNE does not provide any additional effects on pain intensity and disability.
BRAZILIAN JOURNAL OF PHYSICAL THERAPY
(2023)
Article
Orthopedics
S. Z. George, X. Yan, S. Luo, S. A. Olson, E. K. Reinke, M. P. Bolognesi, M. E. Horn
Summary: This study aimed to determine if PROMIS measures can be used to create patient subgroups for individuals seeking orthopaedic care. The results suggest that orthopaedic patient subgroups differing in physical function, pain, and psychosocial distress can be created from as few as four different PROMIS measures. Longitudinal research is necessary to determine whether these subgroups have prognostic validity.