Article
Psychology, Clinical
Melissa Freizinger, Grace B. Jhe, Emily Pluhar, Lisa Mancini
Summary: Eating disorders are serious psychiatric illnesses with high mortality rates. Family-based treatment is recommended as the first-line approach for adolescents with restrictive eating disorders due to its effectiveness and cost efficiency. This treatment method has been successfully adapted for use in various levels of care.
PSYCHOLOGY RESEARCH AND BEHAVIOR MANAGEMENT
(2021)
Article
Nutrition & Dietetics
Norbert Quadflieg, Silke Naab, Sandra Schlegl, Tabea Bauman, Ulrich Voderholzer
Summary: CBT-E involving carers is an effective intervention for adolescents with anorexia nervosa. The treatment results in significant improvements in body weight indices, drive for thinness, and other subscores of the Eating Disorder Inventory. There is also significant improvement in general psychopathology.
Article
Psychology, Developmental
Nathalie Godart, Geraldine Dorard, Jeanne Duclos, Florence Curt, Irene Kaganski, Lisa Minier, Maurice Corcos, Bruno Falissard, Ivan Eisler, Philippe Jeammet, Sylvie Berthoz
Summary: This study compared the long-term effects of standard treatment with the addition of systemic family therapy for adolescents with anorexia nervosa. The results showed that adding systemic family therapy to multidimensional outpatient treatment led to better outcomes in terms of global outcome categories, body mass index, resumption of menses, and mental state score at 54 months follow-up.
JOURNAL OF CHILD PSYCHOLOGY AND PSYCHIATRY
(2022)
Article
Gastroenterology & Hepatology
Farnaz Fouladi, Emily C. Bulik-Sullivan, Elaine M. Glenny, Laura M. Thornton, Kylie K. Reed, Stephanie Thomas, Susan Kleiman, Ashlie Watters, Judy Oakes, Eun-Young Huh, Quyen Tang, Jintong Liu, Zorka Djukic, Lauren Harper, Yesel Trillo-Ordonez, Shan Sun, Ivory Blakely, Philip S. Mehler, Anthony A. Fodor, Lisa M. Tarantino, Cynthia M. Bulik, Ian M. Carroll
Summary: This study investigates the composition of gut microbiota in patients with anorexia nervosa (AN) and its influence on the host. The researchers collected fecal samples from AN patients before and after treatment at two different eating disorder units. The results show that the gut microbiota of AN patients remained distinct from non-eating disorder controls even after treatment. The study highlights the important role of gut microbiota in AN patients and its impact on recovery.
Article
Medicine, General & Internal
Dunja Mairhofer, Michael Zeiler, Julia Philipp, Stefanie Truttmann, Tanja Wittek, Katrin Skala, Michaela Mitterer, Gabriele Schoefbeck, Clarissa Laczkovics, Julia Schwarzenberg, Gudrun Wagner, Andreas Karwautz
Summary: This study evaluated the short-term outcome of a multimodal inpatient treatment concept for adolescents with anorexia nervosa, finding significant improvements in body mass index during the hospital stay. However, differences were observed among remission groups in terms of severity, age, and medication use.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Psychology, Developmental
Adrian Meule, David R. Kolar, Silke Naab, Ulrich Voderholzer
Summary: Current treatment guidelines recommend that inpatients with eating disorders, especially adolescents with anorexia nervosa, should receive treatment at facilities close to their home. However, the impact of distance from home on the treatment outcome of adolescents with anorexia nervosa has not been investigated. This study analyzed data from 142 female adolescent inpatients with anorexia nervosa and found that distance to home did not affect treatment outcomes.
EUROPEAN CHILD & ADOLESCENT PSYCHIATRY
(2022)
Article
Nutrition & Dietetics
Stephanie Proulx-Cabana, Marie-Elaine Metras, Danielle Taddeo, Olivier Jamoulle, Jean-Yves Frappier, Chantal Stheneur
Summary: This study aims to develop an admission protocol for severely malnourished adolescents with Anorexia Nervosa (AN) based on a comprehensive narrative review of current evidence. The protocol includes selective blood tests during the first three days of nutritional rehabilitation, higher initial caloric intake, continuous nasogastric tube feeding for patients with a BMI < 12 kg/m2, monitoring of hypoglycemia for 72 hours, continuous cardiac monitoring for bradycardia <30 BPM, and systematic phosphate supplementation.
Article
Psychology, Clinical
Adrian Meule, Dominic Schrambke, Artur Furst Loredo, Sandra Schlegl, Silke Naab, Ulrich Voderholzer
Summary: Inpatient treatment is highly effective in increasing body weight and decreasing symptoms for adolescents with AN. Treatment effects remain stable or even improve within the first year after discharge, but certain subgroups of patients require special attention to prevent relapse.
EUROPEAN EATING DISORDERS REVIEW
(2021)
Article
Psychiatry
Ulf Wallin, Riitta Holmer
Summary: Long-term follow-up showed that adolescents treated in Family Treatment Apartment (FTA) had lower readmission rates and lower general psychiatric pathology scores, but higher quality of life scores compared to those treated in regular psychiatric inpatient care.
FRONTIERS IN PSYCHIATRY
(2021)
Article
Psychiatry
Valeria Zanna, Giulia Cinelli, Michela Criscuolo, Annamaria Caramadre, Maria Chiara Castiglioni, Ilenia Chianello, Maria Rosaria Marchili, Chiara Casamento Tumeo, Stefano Guolo, Alberto Eugenio Tozzi, Stefano Vicari
Summary: This pilot study compared the impact of high-level care treatment (HLCT) and inpatient treatment (IP) on adolescents with AN, showing that patients in the HLCT group had fewer in-hospital treatment days, higher weight gain, and significant improvement in outcomes at discharge compared to the inpatient group.
FRONTIERS IN PSYCHIATRY
(2021)
Article
Psychology, Clinical
Emily Coopey, George Johnson
Summary: Background research shows that family therapy and multi-family therapy are effective treatments for adolescents with anorexia nervosa. However, little is known about the experiences of young people receiving these treatments in an inpatient setting. This study interviewed five young people receiving treatment on the AN pathway in an inpatient unit, and identified four superordinate themes: 'Process of Understanding', 'Reviving Connection', 'Emerging from the Eating Disorder', and 'Development of I'. The results highlight the importance of both the individual and the role of others in the treatment process, and can inform future service developments.
JOURNAL OF EATING DISORDERS
(2022)
Article
Psychiatry
Liron Litmanovich-Cohen, Amit Yaroslavsky, Liron Roni Halevy-Yosef, Tal Shilton, Adi Enoch-Levy, Daniel Stein
Summary: A study of 61 hospitalized ED patients indicates that participating in a post-hospitalization daycare program may improve the 1-year follow-up outcomes for patients, with more achievers of remission. However, patients who do not complete daycare treatment can also maintain a normal BMI one year later. There were no significant differences between the two groups in terms of social functioning, depression, anxiety, and other aspects.
FRONTIERS IN PSYCHIATRY
(2021)
Article
Health Care Sciences & Services
Magnus Sjogren, Rene Klinkby Stoving
Summary: This study observed 49 patients with anorexia nervosa during a 8-week inpatient treatment, using self-rating measures to assess depressiveness and eating disorder psychopathology. The study found that inpatient treatment was associated with a reduction in depressiveness, which correlated with an improvement in eating disorder pathology but not with weight gain.
JOURNAL OF PERSONALIZED MEDICINE
(2022)
Article
Psychology, Multidisciplinary
Jacopo Pruccoli, Giulia Joy Leone, Cristina Di Sarno, Luigi Vetri, Giuseppe Quatrosi, Michele Roccella, Antonia Parmeggiani
Summary: Two adolescents with anorexia nervosa were treated with Clotiapine, showing varying responses - one experiencing mild adverse reaction and the other showing symptom improvement after 9 months of treatment.
BEHAVIORAL SCIENCES
(2021)
Article
Health Care Sciences & Services
Magnus Sjogren, Ismail Kizilkaya, Rene Klinkby Stoving
Summary: Inpatient weight restoration treatment is associated with a decrease in post-meal anxiety in patients with Anorexia Nervosa, demonstrating an early and clinically significant effect in those who stay in treatment. The study also found that baseline medication or scores of Major Depression Inventory did not affect the results, indicating that BMI increase and reduction in anxiety levels were independent of these factors.
JOURNAL OF PERSONALIZED MEDICINE
(2021)
Article
Psychiatry
Julian Baudinet, Catherine Stewart, Eleanor Bennett, Anna Konstantellou, Rhian Parham, Keren Smith, Katrina Hunt, Ivan Eisler, Mima Simic
Summary: This study found that adolescents in this case series reported high rates of depression, self-harm, and eating disorders. After receiving RO-A treatment, they showed significant improvements in cognitive flexibility, risk aversion, reward processing, and suppression of emotional expression.
Article
Multidisciplinary Sciences
Yolaine Rabat, Igor Sibon, Sylvie Berthoz
Summary: The study found a significant proportion of stroke patients with problematic substance use, including cannabis users. The prevalence of PSD is high, especially for severe depression. The results suggest that baseline tobacco dependence severity may increase the risk of PSD.
SCIENTIFIC REPORTS
(2021)
Review
Psychology, Clinical
Julian Baudinet, Mima Simic, Ivan Eisler
Summary: Formulation, or case conceptualisation, is the collaborative sense-making process that clinicians are constantly engaging in, but may not always prioritize in clinical practice. This process is essential for understanding a patient's specific difficulties, establishing treatment goals, and effectively reviewing treatment progress.
JOURNAL OF EATING DISORDERS
(2021)
Article
Psychology, Developmental
Nathalie Godart, Geraldine Dorard, Jeanne Duclos, Florence Curt, Irene Kaganski, Lisa Minier, Maurice Corcos, Bruno Falissard, Ivan Eisler, Philippe Jeammet, Sylvie Berthoz
Summary: This study compared the long-term effects of standard treatment with the addition of systemic family therapy for adolescents with anorexia nervosa. The results showed that adding systemic family therapy to multidimensional outpatient treatment led to better outcomes in terms of global outcome categories, body mass index, resumption of menses, and mental state score at 54 months follow-up.
JOURNAL OF CHILD PSYCHOLOGY AND PSYCHIATRY
(2022)
Article
Biology
Yolaine Rabat, Sandra Chanraud, Majd Abdallah, Igor Sibon, Sylvie Berthoz
Summary: This review examines the use of Magnetic Resonance Imaging (MRI) to predict smoking cessation outcomes and identifies the insula as a key factor in addiction. Despite the inability to conduct a meta-analysis, this research has the potential to pave the way for personalized prevention therapy for high-risk smokers.
Article
Psychology, Clinical
Mima Simic, Catherine S. Stewart, Anna Konstantellou, John Hodsoll, Ivan Eisler, Julian Baudinet
Summary: This study evaluates the outcomes of a specialist child and adolescent eating disorder service in the UK in a real-world setting. The study finds that the treatment outcomes in this service compare well to those reported in research trials, and that early weight gain is associated with improved outcomes.
JOURNAL OF EATING DISORDERS
(2022)
Article
Psychology, Clinical
Catherine S. Stewart, Julian Baudinet, Alfonce Munuve, Antonia Bell, Anna Konstantellou, Ivan Eisler, Mima Simic
Summary: The study found that young people treated in specialist eating disorder services generally do well at long-term follow-up, especially regarding eating disorders, but less favorably regarding other mental health difficulties. Few reported a diagnosable eating disorder, and the majority performed similarly to their peers in educational and vocational achievements.
JOURNAL OF EATING DISORDERS
(2022)
Article
Psychology, Clinical
Sylvie Berthoz, Anne-Solene Maria, Damien Ringuenet, Lena Bourdier, Isabelle Nicolas, Corinne Blanchet, Christine Foulon, Guillaume Lavoisy, Nathalie Godart, Caroline Barry
Summary: This study aimed to compare the levels of cognitive flexibility and attention to detail between adolescents and adults diagnosed with anorexia nervosa. The results showed no significant differences in neuropsychological test scores between the two groups, even after adjusting for confounding factors. Additionally, cognitive flexibility and attention to detail were not associated with eating disorder symptomatology, depression, anxiety, or obsessive-compulsive symptomatology.
EUROPEAN EATING DISORDERS REVIEW
(2022)
Article
Psychology, Clinical
Lisa Minier, Benjamin Carrot, Solange Cook-Darzens, Sophie Criquillion-Doublet, France Boyer, Vesper Barton-Clegg, Mima Simic, Stamatoula Voulgari, Nathalie Godart, Jeanne Duclos
Summary: The written transmission of therapists' expertise in manuals is an important issue that has received little attention in terms of conceptualization, design, and drafting of therapy manuals. This paper presents a methodology used to design a multi-family therapy program and draft a manual, as well as how consensus was reached regarding the role of food-related symptoms in the program. These efforts resulted in fruitful discussions and the development of a shared theory of treatment.
JOURNAL OF FAMILY THERAPY
(2023)
Article
Biology
Valentine Chirokoff, Georges Di Scala, Joel Swendsen, Bixente Dilharreguy, Sylvie Berthoz, Sandra Chanraud
Summary: This study aimed to investigate the relationship between the reconfiguration of brain connections, learning abilities, confidence in learning, and psychological temperament. The findings suggest that the reconfiguration of resting-state networks is influenced by factors such as learning confidence and anxiety sensitivity.
Article
Biochemistry & Molecular Biology
Louise Jakubiec, Valentine Chirokoff, Majd Abdallah, Ernesto Sanz-Arigita, Maud Dupuy, Joel Swendsen, Sylvie Berthoz, Fabien Gierski, Sarah Guionnet, David Misdrahi, Fuschia Serre, Marc Auriacombe, Melina Fatseas
Summary: This study aimed to investigate the role of deficits in neurocognitive functioning in the craving-use association and relapse vulnerability among individuals with substance use disorders (SUD). The results showed that better executive capacities were associated with a greater propensity to use substances when experiencing craving. The functional connectivity of cerebral networks also interacted with executive performance capacities to influence the magnitude of the craving-use association. Individuals with better executive functioning may be more prone to relapse after craving episodes.
Article
Nutrition & Dietetics
Romain de Rivaz, Joel Swendsen, Sylvie Berthoz, Mathilde Husky, Kathleen Merikangas, Pedro Marques-Vidal
Summary: This study found that there is a bidirectional association between hunger and psychological states, indicating that hunger influences positive psychological states such as feeling active and lively, while positive psychological states can also affect the intensity of hunger. However, no association was found between hunger and negative psychological states such as sadness, anxiety, and anger.
Review
Psychology, Clinical
Tom Jewell, Eleni Apostolidou, Kevser Sadikovic, Kirsty Tahta-Wraith, Sarah Liston, Mima Simic, Ivan Eisler, Peter Fonagy, Isabel Yorke
Summary: Individuals with eating disorders have higher rates of insecure attachment compared to community controls. This systematic review and meta-analysis examined the attachment in eating disorder samples compared to community controls and found that eating disorder samples showed higher rates of insecure attachment across different attachment dimensions. This highlights the importance of considering attachment in understanding and treating eating disorders.
INTERNATIONAL JOURNAL OF EATING DISORDERS
(2023)
Article
Pediatrics
Chantal T. Delaquis, Nathalie Godart, Melina Fatseas, Sylvie Berthoz
Summary: This study investigated the impact of cognitive and interpersonal factors on the development and maintenance of anorexia nervosa in adolescents using network analysis. The findings support the cognitive-interpersonal model and certain premises of the transdiagnostic cognitive-behavioral model.
Article
Psychiatry
Y. Rabat, S. Berthoz, I. Sibon
Summary: This case study highlights the risk of stroke associated with food addiction, suggesting the need to consider addictive-like eating behaviors and related mental disorders in stroke prevention. It emphasizes the importance of addressing dietary habits and psychological well-being in stroke prevention efforts, especially in women who may be more prone to using food as a coping mechanism.
EATING AND WEIGHT DISORDERS-STUDIES ON ANOREXIA BULIMIA AND OBESITY
(2021)