Article
Oncology
Dong-Dong You, Xiao-Li Zhou, Qiao-Qi Wang, Ji-Long Liu
Summary: Although most cells are mononuclear, the nucleus can exist in the form of binucleate or even multinucleate. The male accessory gland of Drosophila is binucleate and CTP synthase (CTPS) forms filamentous cytoophidia in these cells. A point mutation that destroys the formation of cytoophidia changes the nucleation mode of the main cells in Drosophila, indicating a functional link between cytoophidia formation and the maintenance of binucleation.
EXPERIMENTAL CELL RESEARCH
(2023)
Article
Entomology
Dong Wei, Yu-Wei Liu, Su-Yun Zhang, Hui-Qian Xu, Guy Smagghe, Jin-Jun Wang
Summary: The study identified a takeout gene, named Bdtakeout2, highly expressed in the male accessory glands of Bactrocera dorsalis, playing a critical role in male mating behavior and fertility. Treatment with exogenous hormones and photoperiod exposure influenced the expression of Bdtakeout2, affecting male mating success and female fertility.
ENTOMOLOGIA GENERALIS
(2021)
Article
Biology
Jaya Kumari, Pradip Sinha
Summary: Conservation of genetic toolkits in disparate phyla may reveal commonalities in the design of organs, as shown in the development of Drosophila male accessory gland (MAG) which shares similarities with mammalian prostate development, including recruitment of similar genetic pathways like FGFR and expression of posterior Hox genes.
Article
Anatomy & Morphology
Pollyana B. Pimentel, Cornelio S. Santigo, Juliana F. Ferraz, Eliana Morielle-Versute, Sebastiao R. Taboga, Carolina C. Souza, Mateus R. Beguelini
Summary: This study aims to characterize the male reproductive accessory glands (RAGs) of Pteronotus gymnonotus (Mormoopidae: Chiroptera). The results demonstrate that the RAGs of P. gymnonotus are composed of a prostatic complex, urethral glands, bulbourethral glands, and ampullary glands. It is proposed that the RAGs of P. gymnonotus possibly evolved from a common ancestor shared with the families Phyllostomidae and Nocti-lionidae, with the development of an exclusive feature - ampullary glands.
Article
Cell Biology
Maria Molano-Fernandez, Ian D. Hickson, Hector Herranz
Summary: The regulation of the cell division cycle is important for maintaining stable genome and tissue homeostasis. Dysregulation can lead to genomic instability and tissue abnormalities, as shown by upregulation of Cyclin E in the accessory gland of Drosophila melanogaster. Upregulation of Cyclin E causes endoreplication, DNA damage, and mitochondrial defects, resulting in tissue dysplasia.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY
(2023)
Article
Biochemistry & Molecular Biology
Jie Cheng, Peng Zhao, Lin Zhu, Fang Zhu, Zhiqiang Tian, Zhongjian Shen, Xiaoming Liu, Xiaoxia Liu
Summary: In this study, the neuropeptide Corazonin (Crz) and its receptor were characterized in Grapholita molesta, and their role in regulating copulation duration and fertility in males was investigated. Knockdown of Crz or its receptor led to prolonged copulation duration and decreased fertility in males without affecting sperm production. The knockdown also resulted in significantly diminished levels of accessory gland proteins and downregulation of genes involved in serine-type endopeptidase activity in the accessory gland. Furthermore, disruption of sperm activation in the spermatophore of females mated with knockdown males was observed. These findings provide new insights into the functions of Crz signaling in Lepidopteran insects.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2022)
Article
Entomology
Li-Juan Wu, Fan Li, Yue Song, Zhan-Feng Zhang, Yong-Liang Fan, Tong-Xian Liu
Summary: The study identified and analyzed male accessory gland proteins (ACPs) in the diamondback moth, Plutella xylostella. A comparison with ACPs in other insect species revealed some new ACPs. This research provides valuable information for understanding the reproductive physiology of P. xylostella.
Article
Multidisciplinary Sciences
Clement Immarigeon, Yohan Frei, Sofie Y. N. Delbare, Dragan Gligorov, Pedro Machado Almeida, Jasmine Grey, Lea Fabbro, Emi Nagoshi, Jean-Christophe Billeter, Mariana F. Wolfner, Francois Karch, Robert K. Maeda
Summary: Many transcripts previously considered noncoding RNAs are now found to produce peptides with important biological functions, such as the micropeptide encoded by male-specific abdominal RNA. This micropeptide is expressed exclusively in the secondary cells of the male accessory gland of Drosophila, and its loss of function results in defects in sperm competition, highlighting the importance of small peptides in biological processes.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2021)
Article
Entomology
Xiang-Yang Lyu, Xue-Li Wang, Dan-Qian Geng, Hong Jiang, Zhen Zou
Summary: Hormones are found to be involved in the molecular mechanism linking hormones, energy metabolism, and reproduction in male mosquitoes. The receptor of juvenile hormone, Methoprene-tolerant (Met), plays a crucial role in the reproductive development of male mosquitoes. Met influences the fecundity of male mosquitoes by directly upregulating the expression of the gene encoding accessory gland protein, l-asparaginase (ASNase), and by regulating lipid metabolism and the development of the male accessory gland.
Article
Biochemistry & Molecular Biology
Tongtong Chen, Qiqi Jiao, Chenglong Ye, Jiangen Wu, Yuanyuan Zheng, Chuanxin Sun, Peiying Hao, Xiaoping Yu
Summary: This study reveals the expression and function of cuticle protein 21-like (Cpr21L) in the brown planthopper (BPH). The RNA interference of Cpr21L significantly affects BPH nymph survival and male fertility.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Genetics & Heredity
Julie M. Cridland, Alex C. Majane, Li Zhao, David J. Begun
Summary: Research on de novo gene discovery in Drosophila has revealed significant differences in gene abundance and expression between different tissues, particularly in the testis and accessory gland. While other properties such as transcript length and chromosomal distribution are more similar, regulatory mechanisms may vary and interact with selection to produce differences in de novo genes expressed in male reproductive tissues.
Article
Developmental Biology
Sophia A. Praggastis, Hyuck-Jin Nam, Geanette Lam, Myron B. Child, Dean M. Castillo, Carl S. Thummel
Summary: The Drosophila HR39 nuclear receptor is essential for the proper expression of genes encoding male accessory gland proteins, resulting in infertility in HR39 mutant males. This demonstrates the crucial role of HR39 in regulating gene expression and male fertility within the accessory glands. These findings provide insights into mammalian orthologs SF-1 and LRH-1 nuclear receptors, which are also involved in glandular secretions and reproduction.
DEVELOPMENTAL BIOLOGY
(2021)
Review
Andrology
Sandro La Vignera, Andrea Crafa, Rosita A. Condorelli, Federica Barbagallo, Laura M. Mongioi, Rossella Cannarella, Michele Compagnone, Antonio Aversa, Aldo E. Calogero
Summary: Male accessory gland infection/inflammation (MAGI) is a major cause of male infertility, and the importance of ultrasound evaluation in confirming the diagnosis is highly debated. Ultrasound criteria help localize and assess the extent of the inflammatory process, with varying consequences on seminological and symptomatic aspects.
Article
Anatomy & Morphology
Pollyana B. Pimentel, Juliana Filgueira Ferraz, Cornelio Souza Santigo, Emilia Miguel Soares, Eliana Morielle-Versute, Sebastiao R. Taboga, Carolina C. Souza, Mateus R. Beguelini
Summary: Despite being highly diverse and widely distributed, the reproductive accessory glands (RAGs) of bats have received limited attention in research. This study aimed to analyze and compare the composition, anatomy, and histology of male RAGs in three cosmopolitan bat families (Vespertilionidae, Molossidae, and Emballonuridae). The results revealed that the RAGs of these bat species consist of an intra-abdominal prostatic complex, urethral glands, and inguinal bulbourethral glands, but lack ampullary glands or seminal vesicles. The prostatic complex varies in the number of regions and lobed structure among the species.
ANATOMICAL RECORD-ADVANCES IN INTEGRATIVE ANATOMY AND EVOLUTIONARY BIOLOGY
(2023)
Article
Nutrition & Dietetics
Rosita A. Condorelli, Antonio Aversa, Livia Basile, Rossella Cannarella, Laura M. Mongioi, Laura Cimino, Sarah Perelli, Massimiliano Caprio, Sebastiano Cimino, Aldo E. Calogero, Sandro La Vignera
Summary: This study aimed to evaluate the effects of body weight loss on urogenital symptoms in overweight/obese male accessory gland inflammation (MAGI) patients. The results showed that both Mediterranean diet (MedDiet) and very-low-calorie ketogenic diet (VLCKD) improved the symptoms, with VLCKD showing additional improvement in ejaculatory pain/discomfort and sexual dysfunction, as well as greater weight loss.
Article
Genetics & Heredity
Takashi Okumura, Takeshi Sasamura, Momoko Inatomi, Shunya Hozumi, Mitsutoshi Nakamura, Ryo Hatori, Kiichiro Taniguchi, Naotaka Nakazawa, Emiko Suzuki, Reo Maeda, Tomoko Yamakawa, Kenji Matsuno
Article
Genetics & Heredity
Takashi Okumura, Takeshi Sasamura, Momoko Inatomi, Shunya Hozumi, Mitsutoshi Nakamura, Ryo Hatori, Kiichiro Taniguchi, Naotaka Nakazawa, Emiko Suzuki, Reo Maeda, Tomoko Yamakawa, Kenji Matsuno
Article
Developmental Biology
Takashi Okumura, Koji Takeda, Megumi Kuchiki, Marie Akaishi, Kiichiro Taniguchi, Takashi Adachi-Yamada
DEVELOPMENTAL BIOLOGY
(2016)
Article
Developmental Biology
Seiko Sugimori, Aya Hasegawa, Hideki Nakagoshi
MECHANISMS OF DEVELOPMENT
(2016)
Article
Cell Biology
Ayuko Kubo, Mirai Matsuka, Ryunosuke Minami, Fumika Kimura, Rumi Sakata-Niitsu, Akihiko Kokuryo, Kiichiro Taniguchi, Takashi Adachi-Yamada, Hideki Nakagoshi
Article
Zoology
Koji Takeda, Takashi Okumura, Mayu Terahata, Mio Yamaguchi, Kiichiro Taniguchi, Takashi Adachi-Yamada
ZOOLOGICAL SCIENCE
(2018)
Article
Developmental Biology
Kiichiro Taniguchi, Akihiko Kokuryo, Takao Imano, Ryunosuke Minami, Hideki Nakagoshi, Takashi Adachi-Yamada
BMC DEVELOPMENTAL BIOLOGY
(2014)
Article
Developmental Biology
Ryo Hatori, Tadashi Ando, Takeshi Sasamura, Naotaka Nakazawa, Mitsutoshi Nakamura, Kiichiro Taniguchi, Shunya Hozumi, Junichi Kikuta, Masaru Ishii, Kenji Matsuno
MECHANISMS OF DEVELOPMENT
(2014)
Article
Developmental Biology
Naruto Kiritooshi, Takeshi Yorimitsu, Tetsuya Shirai, Oorvashi Roy Puli, Amit Singh, Hideki Nakagoshi
MECHANISMS OF DEVELOPMENT
(2014)
Article
Multidisciplinary Sciences
Takashi Okumura, Koji Takeda, Kiichiro Taniguchi, Takashi Adachi-Yamada
Article
Zoology
Kiichiro Taniguchi, Akihiko Kokuryo, Takao Imano, Hideki Nakagoshi, Takashi Adachi-Yamada
ZOOLOGICAL SCIENCE
(2018)
Article
Multidisciplinary Sciences
Chiaki Iida, Shizue Ohsawa, Kiichiro Taniguchi, Masatoshi Yamamoto, Gines Morata, Tatsushi Igaki
SCIENTIFIC REPORTS
(2019)
Article
Multidisciplinary Sciences
Koji Takeda, Tomoki Furuta, Masaki Hamada, Yo Sato, Kiichiro Taniguchi, Akihiro Tanizawa, Tomomasa Yagi, Takashi Adachi-Yamada
SCIENTIFIC REPORTS
(2020)