Article
Anatomy & Morphology
Alana C. Sharp, Hugo Dutel, Peter J. Watson, Flora Groning, Nick Crumpton, Michael J. Fagan, Susan E. Evans
Summary: Cranial sutures are fibrocellular joints between skull bones that are gradually replaced with bone, facilitating growth and cranial shape change. Our study used computational biomechanical methods to simulate biting in a rat skull and found that the presence of cranial sutures did not significantly alter overall strain gradients across the cranium, but did affect local variations in strain magnitudes and patterns near the sutures. This suggests that the importance of sutures differs in different regions and should be considered in models requiring accurate local strain magnitudes and patterns.
JOURNAL OF MORPHOLOGY
(2023)
Article
Robotics
Emanuele Vignali, Emanuele Gasparotti, Katia Capellini, Benigno Marco Fanni, Luigi Landini, Vincenzo Positano, Simona Celi
Summary: Cardiovascular diseases are the leading cause of death in western countries, and robotic surgery is increasingly important in the field. A deeper understanding of blood vessel material properties is necessary for the advancement of soft robotics applications. Testing different models and implementing weighting procedures have significant impacts on model performance.
INTERNATIONAL JOURNAL OF ROBOTICS RESEARCH
(2021)
Article
Engineering, Biomedical
Anne-Cecile Lesage, Alexis Simmons, Anando Sen, Simran Singh, Melissa Chen, Guillaume Cazoulat, Jeffrey S. Weinberg, Kristy K. Brock
Summary: This study evaluated the accuracy and efficiency of various FEM models in predicting inward brain-shift during neurosurgery. Including non-rigid modeling of the meninges was found to be statistically significant for patients with low-grade gliomas.
PHYSICS IN MEDICINE AND BIOLOGY
(2021)
Review
Cell Biology
Heather E. White, Anjali Goswami, Abigail S. Tucker
Summary: Phenotypic variation in mammals is influenced by their ecological diversification, with the skull playing a crucial role in supporting species survival. Sutures between cranial bones are important in growth and brain development, shaping overall skull morphology and function. The developmental mechanisms of sutures have a significant impact on cranial diversity and evolutionary patterns.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY
(2021)
Article
Engineering, Biomedical
Songbai Ji, Mazdak Ghajari, Haojie Mao, Reuben H. Kraft, Marzieh Hajiaghamemar, Matthew B. Panzer, Remy Willinger, Michael D. Gilchrist, Svein Kleiven, Joel D. Stitzel
Summary: Head acceleration measurement sensors are widely used in contact sports to monitor head kinematic exposure. The use of validated brain models and physics-based computational simulations help translate head impact kinematics into brain mechanical responses and study injury mechanisms. This study reviews legacy and contemporary brain biomechanical models, discusses their development and validation, and recommends their use in conjunction with kinematic sensor data for understanding mTBI and subconcussions.
ANNALS OF BIOMEDICAL ENGINEERING
(2022)
Article
Engineering, Biomedical
Pieter Ansoms, Mojtaba Barzegari, Jos Vander Sloten, Liesbet Geris
Summary: This study presents an in silico strategy for designing and studying biodegradable metal implants for fracture fixation. By combining three separate models, patient-specific biodegradable fixation implants can be designed to deliver the desired mechanical behavior in coordination with bone regeneration.
JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS
(2023)
Article
Biotechnology & Applied Microbiology
Jinfang Wu, Wenxuan Fang, Huiwen Xu, Xiaode Liu, Dongliang Zhao, Qiguo Rong
Summary: The study revealed that with increased myopia reduction, corneal curvature, and thickness, the stress response of the central and peripheral cornea significantly changed during orthokeratology. The factors influencing corneal response ranked in order of myopia reduction, corneal curvature, and corneal thickness.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2021)
Review
Multidisciplinary Sciences
Jordi Marce-Nogue
Summary: Finite element analysis (FEA) has become a well-established technique in the fields of palaeontology, anthropology, and evolutionary biology. However, there is a lack of application of nonlinear materials and dynamic structural problems in these fields. This review aims to highlight the usefulness of nonlinearities and showcase the potential applications and research topics in FEA models for researchers in functional morphology and biomechanics.
Article
Computer Science, Interdisciplinary Applications
Farah Alkhatib, Adam Wittek, Benjamin F. Zwick, George C. Bourantas, Karol Miller
Summary: Aortic wall stress is an important factor in assessing the risk of abdominal aortic aneurysm (AAA) rupture. Finite element analysis is commonly used for its computation, but the impact of finite element formulation, element quality, and mesh construction methods on the accuracy and efficiency of the computation has been largely overlooked. This study compares the results of aortic wall stress calculation for ten AAA patients using tetrahedral and hexahedral meshes under varying finite element formulations, shape functions, spatial integration schemes, and number of elements across the wall thickness.
COMPUTER METHODS IN BIOMECHANICS AND BIOMEDICAL ENGINEERING
(2023)
Article
Engineering, Biomedical
Zhang Zhiguo, Tao Ruizhi, Zhou Fan, Sun Wenchao, Wei Maoning
Summary: Obstructive sleep apnea syndrome (OSAS) is caused by upper airway obstruction during sleep and can lead to death. The mandibular advancement device (MAD) is commonly used to treat mild to moderate OSAS due to its compliance, portability, and low cost. However, long-term use of MAD may cause adverse effects such as occlusal changes and periodontitis. This study used computer numerical simulations and a nonhomogeneous alveolar bone model to analyze the biomechanical mechanisms underlying these side effects and provided insights for oral health protection in MAD treatment.
JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS
(2023)
Article
Biotechnology & Applied Microbiology
Xiaoli Zhu, Kangli Sun, Xin Xia, Yu Chen, Anqiang Sun, Xingming Chen
Summary: This study tested the mechanical properties of clavicular periosteum and constructed a 3D trachea geometry based on preoperative CT scanning images. The biomechanical loads on the repaired trachea may cause collapse or stenosis due to the softer and different mechanical properties of the periosteum. Numerical simulations provide references for biomechanical evaluation of trachea reconstruction surgery and may expand surgical indications.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2023)
Article
Computer Science, Interdisciplinary Applications
DaiZhu Yuan, ZhanYu Wu, Long Yang, Qiang Zou, DaWei Hua, ZiHao Zou, Chuan Ye
Summary: This study investigated the effects of different core decompression drilling locations and diameters on mechanical stability using finite element analysis. It was found that femoral stiffness decreased with increasing drilling diameters, while maximum equivalent stress increased. A safe drilling parameter range suitable for most patients was proposed.
COMPUTER METHODS AND PROGRAMS IN BIOMEDICINE
(2022)
Article
Engineering, Multidisciplinary
Melissa M. Gibbons, Diana A. Chen
Summary: This study investigates the effects of increasing archway segmentation on the mechanical response of the overall structure and explores the impact of displacement on the stiffness and toughness. The research provides insights for the development of bio-inspired impact-resistant helmets.
Article
Endocrinology & Metabolism
Sei Yano, Yusuke Matsuura, Shigeo Hagiwara, Junichi Nakamura, Yuya Kawarai, Takane Suzuki, Keijiro Kanno, Jumpei Shoda, Yousuke Tsurumi, Seiji Ohtori
Summary: This study used cadaveric mechanical testing and finite element analysis to investigate the relationship between fall direction and proximal femur fracture type. The results showed that trochanteric fractures were more likely to occur following a posterolateral fall than a lateral fall.
Article
Chemistry, Multidisciplinary
Norihiro Nishida, Muzammil Mumtaz, Sudharshan Tripathi, Amey Kelkar, Takashi Sakai, Vijay K. Goel
Summary: Cervical laminoplasty may cause ligament damage during surgery, leading to increased biomechanical stresses in the cervical spine, especially during flexion motion.
APPLIED SCIENCES-BASEL
(2021)
Article
Biology
Thomas G. Davies, Imran A. Rahman, Stephan Lautenschlager, John A. Cunningham, Robert J. Asher, Paul M. Barrett, Karl T. Bates, Stefan Bengtson, Roger B. J. Benson, Doug M. Boyer, Jose Braga, Jen A. Bright, Leon P. A. M. Claessens, Philip G. Cox, Xi-Ping Dong, Alistair R. Evans, Peter L. Falkingham, Matt Friedman, Russell J. Garwood, Anjali Goswami, John R. Hutchinson, Nathan S. Jeffery, Zerina Johanson, Renaud Lebrun, Carlos Martinez-Perez, Jesus Marugan-Lobon, Paul M. O'Higgins, Brian Metscher, Maeva Orliac, Timothy B. Rowe, Martin Rucklin, Marcelo R. Sanchez-Villagra, Neil H. Shubin, Selena Y. Smith, J. Matthias Starck, Chris Stringer, Adam P. Summers, Mark D. Sutton, Stig A. Walsh, Vera Weisbecker, Lawrence M. Witmer, Stephen Wroe, Zongjun Yin, Emily J. Rayfield, Philip C. J. Donoghue
PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES
(2017)
Article
Ecology
A. M. Chira, C. R. Cooney, J. A. Bright, E. J. R. Capp, E. C. Hughes, C. J. A. Moody, L. O. Nouri, Z. K. Varley, G. H. Thomas
Article
Multidisciplinary Sciences
Meena A. Madan, Emily J. Rayfield, Jen A. Bright
SCIENTIFIC REPORTS
(2017)
Article
Ecology
Guillermo Navalon, Jen A. Bright, Jesus Marugan-Lobon, Emily J. Rayfield
Article
Evolutionary Biology
Jen A. Bright, Jesus Marugan-Lobon, Emily J. Rayfield, Samuel N. Cobb
BMC EVOLUTIONARY BIOLOGY
(2019)
Article
Ecology
Guillermo Navalon, Jesus Marugan-Lobon, Jen A. Bright, Christopher R. Cooney, Emily J. Rayfield
NATURE ECOLOGY & EVOLUTION
(2020)
Article
Biology
Case Vincent Miller, Michael Pittman, Thomas G. Kaye, Xiaoli Wang, Jen A. Bright, Xiaoting Zheng
COMMUNICATIONS BIOLOGY
(2020)
Article
Biology
Guillermo Navalon, Sergio M. Nebreda, Jen A. Bright, Matteo Fabbri, Roger B. J. Benson, Bhart-Anjan Bhullar, Jesus Marugan-Lobon, Emily J. Rayfield
Summary: The evolutionary role of ontogeny in the avian skull origin is important, but its influence in subsequent bird evolution remains largely unexplored. Nightbirds exhibit a wide range of craniofacial morphologies that undergo significant ontogenetic shape changes, diverging from common avian patterns. The cranial morphology of many adult nightbirds appears juvenile-like due to convergent evolution, while hummingbirds show a unique evolution of cranial shape originating from a reversal to a typical avian ontogenetic trajectory.
PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES
(2021)
Article
Biology
Case Vincent Miller, Michael Pittman, Xiaoli Wang, Xiaoting Zheng, Jen A. Bright
Summary: This study investigates the diet of extinct birds by using four different proxies to determine their feeding habits. By studying the characteristics of extant birds and applying them to the longipterygid birds, the researchers were able to reveal the diet types and behaviors of these extinct birds.
Article
Ecology
Emma C. Hughes, David P. Edwards, Jen A. Bright, Elliot J. R. Capp, Christopher R. Cooney, Zoe K. Varley, Gavin H. Thomas
Summary: Understanding the origins and conservation of morphological diversity is crucial for determining biogeographical patterns, evolutionary processes, and environmental factors. A study on bird species found that avian morphological diversity is unevenly distributed globally, with dense species packing in tropical hotspots. These regions also exhibit high phenotypic diversity. Evolutionary history plays a key role in shaping these patterns, with old species contributing to niche expansion and young species contributing to niche packing.
Article
Anatomy & Morphology
Gregory S. Herbert, Stephen A. Hill, Maria Jose Pio, Ryan Carney, Amber Carlson, Elis Newham, Jen A. Bright
Summary: Several families of neogastropod mollusks have evolved the ability to drill through prey skeletons using their own feeding teeth. Researchers have discovered new articulating surfaces in the teeth of neogastropod mollusks, including saddle joints and tongue-and-groove joints, which optimize contact surface area and disperse impact forces during drilling. This finding provides new insight into the functional interactions between teeth and improves our understanding of predatory feeding in neogastropods.
JOURNAL OF MORPHOLOGY
(2023)
Meeting Abstract
Anatomy & Morphology
G. Navalon, S. M. Nebreda, J. A. Bright, J. Marugan-Lobon, M. Fabbri, B. A. Bhullar, E. J. Rayfield
JOURNAL OF MORPHOLOGY
(2019)
Meeting Abstract
Anatomy & Morphology
M. Hanson, J. A. Bright, R. M. Carney, R. N. Felice, A. Goswami, D. A. Burnham, B-A S. Bhullar
JOURNAL OF MORPHOLOGY
(2019)
Meeting Abstract
Anatomy & Morphology
J. A. Bright, D. C. Simkins
JOURNAL OF MORPHOLOGY
(2019)
Meeting Abstract
Zoology
J. A. Bright
INTEGRATIVE AND COMPARATIVE BIOLOGY
(2019)