Predicting P-Glycoprotein-Mediated Drug Transport Based On Support Vector Machine and Three-Dimensional Crystal Structure of P-glycoprotein

Homology modeling and binding site assessment of the human P-glycoprotein

(2011) Ákos Tarcsay et al.   Future Medicinal Chemistry

Exhaustive Sampling of Docking Poses Reveals Binding Hypotheses for Propafenone Type Inhibitors of P-Glycoprotein

(2011) Freya Klepsch et al.   PLoS Computational Biology

A tutorial on support vector machine-based methods for classification problems in chemometrics

(2010) Jan Luts et al.   ANALYTICA CHIMICA ACTA

Human P-glycoprotein is active when the two halves are clamped together in the closed conformation

(2010) Tip W. Loo et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Membrane transporters in drug development

(2010)   NATURE REVIEWS DRUG DISCOVERY

Prediction of cytochrome P450 isoform responsible for metabolizing a drug molecule

(2010) Nitish K Mishra et al.   BMC Pharmacology & Toxicology

Identification of Residues in the Drug Translocation Pathway of the Human Multidrug Resistance P-glycoprotein by Arginine Mutagenesis

(2009) Tip W. Loo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structure of P-Glycoprotein Reveals a Molecular Basis for Poly-Specific Drug Binding

(2009) S. G. Aller et al.   SCIENCE

Application of the PM6 semi-empirical method to modeling proteins enhances docking accuracy of AutoDock

(2009) Zsolt Bikadi et al.   Journal of Cheminformatics