Article
Agriculture, Dairy & Animal Science
T. Imbabi, A. Hassan, O. Ahmed-Farid, O. El-Garhy, I Sabeq, M. Moustafa, A. Mohammadein, N. Hassan, A. Osman, M. Sitohy
Summary: The study found that supplementing lower doses of dietary BHA can promote growth and meat quality in rabbits by maintaining redox balance. The range of 50-100 mg/kg may be considered a safe and effective feed additive as well as an attenuator of oxidative stress.
Review
Cell Biology
Qian Li, Nengxian Shi, Chen Cai, Mingming Zhang, Jing He, Ying Tan, Weijun Fu
Summary: Pyroptosis is a gene-regulated cell death process dependent on Caspase, which leads to the production of proinflammatory mediators. Mitochondria also play a crucial role in cell death, with mitochondrial outer membrane permeabilization being a key mechanism. Investigating the roles of mitochondria in pyroptosis can provide new strategies for regulating cell death with potential clinical benefits.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY
(2021)
Article
Biotechnology & Applied Microbiology
Juliang He, Jian Guan, Shian Liao, Zhenjie Wu, Bin Liu, Hao Mo, Zhenchao Yuan
Summary: The study revealed that CCDC144NL-AS1 plays an oncogenic role in osteosarcoma by binding with miR-490-3p and increasing HMGA2 expression. Suppression of CCDC144NL-AS1 expression can inhibit proliferation, migration, and invasion of osteosarcoma cells, while promoting apoptosis.
ONCOTARGETS AND THERAPY
(2021)
Article
Urology & Nephrology
Usman J. Wudil, Muktar H. Aliyu, Heather L. Prigmore, Donna J. Ingles, Aima A. Ahonkhai, Baba M. Musa, Hamza Muhammad, Mahmoud U. Sani, Aisha M. Nalado, Aliyu Abdu, Kabiru Abdussalam, Bryan E. Shepherd, Faisal S. Dankishiya, Anna M. Burgner, T. Alp Ikizler, Christina M. Wyatt, Jeffrey B. Kopp, Paul L. Kimmel, Cheryl A. Winkler, C. William Wester
Summary: The study found that among HIV-positive Nigerian adults, the prevalence of APOL1 high-risk genotype was 6.2%, with significant differences among ethnic groups. The APOL1 high-risk genotype was strongly associated with albuminuria and estimated glomerular filtration rate.
KIDNEY INTERNATIONAL
(2021)
Article
Cell Biology
Lauren G. Chukrallah, Aditi Badrinath, Gabrielle G. Vittor, Elizabeth M. Snyder
Summary: This study identifies ADAD2 as a late meiotic male germ cell-specific RNA-binding protein that plays a crucial role in maintaining the XY-body formation and post-meiotic germ cell differentiation. Loss of ADAD2 leads to defective translation of Mdc1, resulting in the failure of maintaining the XY-body and ultimately causing abnormal heterochromatin and cell death in post-meiotic germ cells.
JOURNAL OF CELL SCIENCE
(2022)
Article
Virology
Hui Jiang, Ya-Fang Mei
Summary: SARS-CoV-2 infection inhibits adaptive immunity and the spike protein may affect adaptive immunity by impeding DNA damage repair through inhibiting key DNA repair proteins' recruitment. The spike protein was found to localize in the nucleus and inhibit DNA damage repair, which may have implications for virus vaccines.
Article
Engineering, Chemical
Ruiliang Cao, Xueqing Yang, Kunmei Su, Zhenhuan Li
Summary: In this study, 2,5-furandicarboxylic acid (FDCA) was used to prepare a furan-based polyamide material, and PA10F membranes with excellent performance were fabricated using non solvent induced phase separation (NIPS) method. The PA10F membrane showed high rejection rates for different molecular sized dyes and excellent anti-fouling performance.
JOURNAL OF MEMBRANE SCIENCE
(2022)
Article
Biochemistry & Molecular Biology
Arpita Ghosh, Satya Prakash Pandey, Asgar Hussain Ansari, Jennifer Seematti Sundar, Praveen Singh, Yasmeen Khan, Mary Krishna Ekka, Debojyoti Chakraborty, Souvik Maiti
Summary: The study identified three conserved and stable rG4 structures in the 3' region of MALAT1 that regulate alternative splicing, and demonstrated the importance of rG4s in the localization of NCL and NPM to nuclear speckles. Disruption of rG4 in MALAT1 resulted in altered pre-mRNA splicing of endogenous genes, similar to NCL knockdown.
NUCLEIC ACIDS RESEARCH
(2022)
Article
Multidisciplinary Sciences
Yinzhao Wang, Gunter Wegener, Tom A. Williams, Ruize Xie, Jialin Hou, Fengping Wang, Xiang Xiao
Summary: Methanogens are believed to have originated in the late Hadean or early Archean eons, and have evolved various metabolic pathways that play a crucial role in climate stability. Horizontal gene transfer likely led to the spread of alkane metabolism genes among different archaeal clades.
Article
Chemistry, Inorganic & Nuclear
Chih-Shan Tan, Michael H. Huang
Summary: DFT calculations on different planes of Cu2O crystals reveal varying electronic band structures, surface distortions, and valence band bending, explaining the facet-dependent electrical properties. PDOS diagrams show variations in frontier orbital electron energy distribution among different plane layers.
INORGANIC CHEMISTRY FRONTIERS
(2021)
Article
Environmental Sciences
Miklas Scholz
Summary: This study aims to address urgent water and food security challenges through the development of sustainable management solutions. They found that climate has different impacts on different types of wetlands and developed crop yield prediction models using remote sensing technology. Current serious game applications need improvement. Overall, the project improves water and food security by adapting agriculture to climate change, recycling nutrients, and providing educational tools to farmers.
Article
Oncology
Jiayi Li, Shuxia Fan, Shuang Liu, Guang Yang, Qingsong Jin, Zhen Xiao
Summary: NOP14-AS1 is upregulated in TSCC tissues and cell lines, with high expression linked to shorter overall survival. Depletion of NOP14-AS1 promotes apoptosis and inhibits proliferation, migration, and invasion in TSCC cells. Mechanistically, NOP14-AS1 functions as a competing endogenous RNA by targeting the miR-665/HMGB3 axis.
CANCER MANAGEMENT AND RESEARCH
(2021)
Article
Medicine, General & Internal
Chaolin Huang, Lixue Huang, Yeming Wang, Xia Li, Lili Ren, Xiaoying Gu, Liang Kang, Li Guo, Min Liu, Xing Zhou, Jianfeng Luo, Zhenghui Huang, Shengjin Tu, Yue Zhao, Li Chen, Decui Xu, Yanping Li, Caihong Li, Lu Peng, Yong Li, Wuxiang Xie, Dan Cui, Lianhan Shang, Guohui Fan, Jiuyang Xu, Geng Wang, Ying Wang, Jingchuan Zhong, Chen Wang, Jianwei Wang, Dingyu Zhang, Bin Cao
Summary: This study aimed to investigate the long-term health consequences of discharged COVID-19 patients and associated risk factors, particularly disease severity. Patients with more severe illness during hospitalization showed more severe impaired pulmonary diffusion capacities and abnormal chest imaging manifestations, highlighting the need for targeted interventions for long-term recovery.
Article
Multidisciplinary Sciences
Rahmad Syah, Marischa Elveny, Mahyuddin K. M. Nasution, Vadim V. Ponkratov, Mariya Yurievna Kuznetsova, Andrey Leonidovich Poltarykhin, Meisam Babanezhad
Summary: This paper focuses on the application of artificial intelligence in the numerical modeling of nanofluid flows, optimizing the drawbacks of computational fluid dynamics using machine learning techniques. The PSOFIS method is used to predict velocity profiles under specific boundary conditions, showcasing improved performance in CFD data prediction compared to traditional calculations.
SCIENTIFIC REPORTS
(2021)
Article
Immunology
Harald Walach, Rainer J. Klement, Wouter Aukema
Summary: Vaccination may lead to death, with a much higher number of vaccinations needed to prevent death compared with preventing COVID-19 cases. The rate of adverse reactions is relatively high. The current vaccination policy is facing challenges and controversies.
Review
Medicine, General & Internal
Ourania Romanidou, Martina Imbimbo, Giannis Mountzios, Aidalena Abidin, Floriana Morgillo, Raffaele Califano
BRITISH MEDICAL BULLETIN
(2016)
Article
Oncology
Cesare Gridelli, Antonio Rossi, Fortunato Ciardiello, Filippo De Marinis, Lucio Crino, Alessandro Morabito, Floriana Morgillo, Agnese Montanino, Gennaro Daniele, Maria Carmela Piccirillo, Nicola Normanno, Ciro Gallo, Francesco Perrone
CLINICAL LUNG CANCER
(2016)
Article
Pharmacology & Pharmacy
V. Gambardella, V. Sforza, T. Troiani, G. Martini, S. Napolitano, C. Cardone, M. L. Ferrara, A. Nappi, A. Manzo, A. Capasso, F. Morgillo, S. Rosello, A. Cervantes, F. Ciardiello, E. Martinelli
DRUGS OF THE FUTURE
(2016)
Article
Oncology
Morena Fasano, Alessio Fabozzi, Guido Giordano, Filippo Venturini, Gaetano Aurilio, Flavia Cantile, Teresa Fabozzi, Vincenzo Ricci, Giuseppe Santabarbara, Floriana Morgillo, Fortunato Ciardiello, Ferdinando De Vita
Article
Chemistry, Medicinal
Floriana Morgillo, Giorgio Amendola, Carminia Maria Della Corte, Chiara Giacomelli, Lorenzo Botta, Salvatore Di Maro, Anna Messere, Vincenza Ciaramella, Sabrina Taliani, Luciana Marinelli, Maria Letizia Trincavelli, Claudia Martini, Ettore Novellino, Fortunato Ciardiello, Sandro Cosconati
JOURNAL OF MEDICINAL CHEMISTRY
(2017)
Review
Gastroenterology & Hepatology
Giulia Martini, Teresa Troiani, Claudia Cardone, Pietropaolo Vitiello, Vincenzo Sforza, Davide Ciardiello, Stefania Napolitano, Carminia Maria Della Corte, Floriana Morgillo, Antonio Raucci, Antonio Cuomo, Francesco Selvaggi, Fortunato Ciardiello, Erika Martinelli
WORLD JOURNAL OF GASTROENTEROLOGY
(2017)
Review
Gastroenterology & Hepatology
Carminia Maria Della Corte, Giuseppe Viscardi, Federica Papaccio, Giovanna Esposito, Giulia Martini, Davide Ciardiello, Erika Martinelli, Fortunato Ciardiello, Floriana Morgillo
WORLD JOURNAL OF GASTROENTEROLOGY
(2017)
Article
Oncology
Carminia Maria Della Corte, Umberto Malapelle, Elena Vigliar, Francesco Pepe, Giancarlo Troncone, Vincenza Ciaramella, Teresa Troiani, Erika Martinelli, Valentina Belli, Fortunato Ciardiello, Floriana Morgillo
Article
Oncology
Stefania Napolitano, Giulia Martini, Erika Martinelli, Carminia Maria Della Corte, Floriana Morgillo, Valentina Belli, Claudia Cardone, Nunzia Matrone, Fortunato Ciardiello, Teresa Troiani
Article
Oncology
Floriana Morgillo, Carminia Maria Della Corte, Anna Diana, Concetta di Mauro, Vincenza Ciaramella, Giusi Barra, Valentina Belli, Elisena Franzese, Roberto Bianco, Evaristo Maiello, Ferdinando De Vita, Fortunato Ciardiello, Michele Orditura
Review
Biochemistry & Molecular Biology
Carminia Maria Della Corte, Giuseppe Viscardi, Raimondo Di Liello, Morena Fasano, Erika Martinelli, Teresa Troiani, Fortunato Ciardiello, Floriana Morgillo
Article
Multidisciplinary Sciences
Brigida D'Abrosca, Vincenza Ciaramella, Vittoria Graziani, Federica Papaccio, Carminia Maria Della Corte, Nicoletta Potenza, Antonio Fiorentino, Fortunato Ciardiello, Floriana Morgillo
SCIENTIFIC REPORTS
(2019)
Article
Cell Biology
A. Ronchi, I. Cozzolino, M. Montella, G. Vicidomini, F. Morgillo, C. M. Della Corte, R. Franco, M. Accardo
Review
Oncology
Erika Martinelli, Floriana Morgillo, Teresa Troiani, Fortunato Ciardiello
CANCER TREATMENT REVIEWS
(2017)
Article
Oncology
Carminia Maria Della Corte, Vincenza Ciaramella, Concetta Di Mauro, Maria Domenica Castellone, Federica Papaccio, Morena Fasano, Ferdinando Carlo Sasso, Erika Martinelli, Teresa Troiani, Ferdinando De Vita, Michele Orditura, Roberto Bianco, Fortunato Ciardiello, Floriana Morgillo