Defective Fluid Secretion from Submucosal Glands of Nasal Turbinates from CFTR-/- and CFTRΔF508/ΔF508 Pigs

The  F508 Mutation Causes CFTR Misprocessing and Cystic Fibrosis-Like Disease in Pigs

(2011) L. S. Ostedgaard et al.   Science Translational Medicine

Pathology of Gastrointestinal Organs in a Porcine Model of Cystic Fibrosis

(2010) David K. Meyerholz et al.   AMERICAN JOURNAL OF PATHOLOGY

Mucus secretion from individual submucosal glands of the ferret trachea

(2010) Hyung-Ju Cho et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Properties of substance P-stimulated mucus secretion from porcine tracheal submucosal glands

(2010) Monal Khansaheb et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Loss of Cystic Fibrosis Transmembrane Conductance Regulator Function Produces Abnormalities in Tracheal Development in Neonatal Pigs and Young Children

(2010) David K. Meyerholz et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Clonal epidemiology of Pseudomonas aeruginosa in cystic fibrosis

(2010) Nina Cramer et al.   INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY

Disease phenotype of a ferret CFTR-knockout model of cystic fibrosis

(2010) Xingshen Sun et al.   JOURNAL OF CLINICAL INVESTIGATION

Hyposecretion of fluid from tracheal submucosal glands of CFTR-deficient pigs

(2010) Nam Soo Joo et al.   JOURNAL OF CLINICAL INVESTIGATION

cAMP-activated Ca2+ signaling is required for CFTR-mediated serous cell fluid secretion in porcine and human airways

(2010) Robert J. Lee et al.   JOURNAL OF CLINICAL INVESTIGATION

Upper and lower airway cultures in children with cystic fibrosis: Do not neglect the upper airways

(2010) Hilde J.C. Bonestroo et al.   Journal of Cystic Fibrosis

Effect of VX-770 in Persons with Cystic Fibrosis and the G551D-CFTRMutation

(2010) Frank J. Accurso et al.   NEW ENGLAND JOURNAL OF MEDICINE

Cystic Fibrosis Pigs Develop Lung Disease and Exhibit Defective Bacterial Eradication at Birth

(2010) D. A. Stoltz et al.   Science Translational Medicine

Substance P stimulates human airway submucosal gland secretion mainly via a CFTR-dependent process

(2009) Jae Young Choi et al.   JOURNAL OF CLINICAL INVESTIGATION

First colonisation with P. aeruginosa – only detected in the upper airways – eradicated with sinonasal inhalation of Tobramycin

(2009) J.G. Mainz et al.   Journal of Cystic Fibrosis

Management of chronic rhinosinusitis in CF

(2009) Jochen G. Mainz et al.   Journal of Cystic Fibrosis

Upper airway {middle dot} 2: Bronchiectasis, cystic fibrosis and sinusitis

(2009) M R Loebinger et al.   THORAX

Concordant genotype of upper and lower airways P aeruginosa and S aureus isolates in cystic fibrosis

(2009) J G Mainz et al.   THORAX

The porcine lung as a potential model for cystic fibrosis

(2008) Christopher S. Rogers et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Sinus surgery in Cystic Fibrosis patients: Comparison of sinus and lower airway cultures

(2008) Brianne Barnett Roby et al.   INTERNATIONAL JOURNAL OF PEDIATRIC OTORHINOLARYNGOLOGY

Production of CFTR-null and CFTR-ΔF508 heterozygous pigs by adeno-associated virus–mediated gene targeting and somatic cell nuclear transfer

(2008) Christopher S. Rogers et al.   JOURNAL OF CLINICAL INVESTIGATION

Disruption of the CFTR Gene Produces a Model of Cystic Fibrosis in Newborn Pigs

(2008) C. S. Rogers et al.   SCIENCE

Distribution and numbers of mucous glands in the horse trachea

(2007) J. H. WIDDICOMBE et al.   EQUINE VETERINARY JOURNAL