Glucose-Raising Genetic Variants in MADD and ADCY5 Impair Conversion of Proinsulin to Insulin

The genetics of type 2 diabetes: what have we learned from GWAS?

(2010) Liana K. Billings et al.   Annals of the New York Academy of Sciences

MTNR1B rs10830963 is associated with fasting plasma glucose, HbA1Cand impaired beta-cell function in Chinese Hans from Shanghai

(2010) Chen Liu et al.   BMC Medical Genetics

Glycemia Determines the Effect of Type 2 Diabetes Risk Genes on Insulin Secretion

(2010) M. Heni et al.   DIABETES

Detailed Physiologic Characterization Reveals Diverse Mechanisms for Novel Genetic Loci Regulating Glucose and Insulin Metabolism in Humans

(2010) E. Ingelsson et al.   DIABETES

Type 2 diabetes risk alleles near ADCY5, CDKAL1 and HHEX-IDE are associated with reduced birthweight

(2010) E. A. Andersson et al.   DIABETOLOGIA

A structural overview of the PDI family of proteins

(2010) Guennadi Kozlov et al.   FEBS Journal

Biophysical alteration of the secretory track in β-cells due to molecular overcrowding: the relevance for diabetes

(2010) Constantin Ionescu-Tirgoviste et al.   Integrative Biology

The Impact of Genetic Variation in theG6PC2Gene on Insulin Secretion Depends on Glycemia

(2010) Martin Heni et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Genetic variation within the NR1H2 gene encoding liver X receptor β associates with insulin secretion in subjects at increased risk for type 2 diabetes

(2010) Caroline Ketterer et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

(2010) Josée Dupuis et al.   NATURE GENETICS

Genomics, Type 2 Diabetes, and Obesity

(2010) Mark I. McCarthy   NEW ENGLAND JOURNAL OF MEDICINE

Evaluation of Fasting State-/Oral Glucose Tolerance Test-Derived Measures of Insulin Release for the Detection of Genetically Impaired β-Cell Function

(2010) Silke A. Herzberg-Schäfer et al.   PLoS One

Association of 18 Confirmed Susceptibility Loci for Type 2 Diabetes With Indices of Insulin Release, Proinsulin Conversion, and Insulin Sensitivity in 5,327 Nondiabetic Finnish Men

(2009) A. Stancakova et al.   DIABETES

Pathomechanisms of Type 2 Diabetes Genes

(2009) Harald Staiger et al.   ENDOCRINE REVIEWS

Finding the missing heritability of complex diseases

(2009) Teri A. Manolio et al.   NATURE

The Unfolded Protein Response: A Pathway That Links Insulin Demand with β-Cell Failure and Diabetes

(2008) Donalyn Scheuner et al.   ENDOCRINE REVIEWS