期刊
PLOS ONE
卷 6, 期 9, 页码 -出版社
PUBLIC LIBRARY SCIENCE
DOI: 10.1371/journal.pone.0024941
关键词
-
资金
- National Institutes of Health (NIH) [P41RR14075, K25MH072941, K01AT003459, 1RO1-NS045130-01, T32GM007484]
- National Science Foundation (NSF) [0316933]
- Osher Institute
- Athinoula A. Martinos Center for Biomedical Imaging
- McGovern Institute for Brain Research
- Division Of Integrative Organismal Systems
- Direct For Biological Sciences [0316933] Funding Source: National Science Foundation
Background: Behavioral paradigms applied during human recordings in electro- and magneto-encephalography (EEG and MEG) typically require 1-2 hours of data collection. Over this time scale, the natural fluctuations in brain state or rapid learning effects could impact measured signals, but are seldom analyzed. Methods and Findings: We investigated within-session dynamics of neocortical alpha (7-14 Hz) rhythms and their allocation with cued-attention using MEG recorded from primary somatosensory neocortex (SI) in humans. We found that there were significant and systematic changes across a single similar to 1 hour recording session in several dimensions, including increased alpha power, increased differentiation in attention-induced alpha allocation, increased distinction in immediate time-locked post-cue evoked responses in SI to different visual cues, and enhanced power in the immediate cue-locked alpha band frequency response. Further, comparison of two commonly used baseline methods showed that conclusions on the evolution of alpha dynamics across a session were dependent on the normalization method used. Conclusions: These findings are important not only as they relate to studies of oscillations in SI, they also provide a robust example of the type of dynamic changes in brain measures within a single session that are overlooked in most human brain imaging/recording studies.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据