Therapeutic Effects of Novel Sphingosine-1-Phosphate Receptor Agonist W-061 in Murine DSS Colitis

The prediction of human response to ONO-4641, a sphingosine 1-phosphate receptor modulator, from preclinical data based on pharmacokinetic-pharmacodynamic modeling

(2010) Tomoya Ohno et al.   BIOPHARMACEUTICS & DRUG DISPOSITION

A Placebo-Controlled Trial of Oral Fingolimod in Relapsing Multiple Sclerosis

(2010) Ludwig Kappos et al.   NEW ENGLAND JOURNAL OF MEDICINE

Infliximab, Azathioprine, or Combination Therapy for Crohn's Disease

(2010) Jean Frédéric Colombel et al.   NEW ENGLAND JOURNAL OF MEDICINE

A protective function for interleukin 17A in T cell–mediated intestinal inflammation

(2009) William O'Connor Jr et al.   NATURE IMMUNOLOGY

IL-17 as a future therapeutic target for rheumatoid arthritis

(2009) Wim B. van den Berg et al.   Nature Reviews Rheumatology

Involvement of IL-17A in the pathogenesis of DSS-induced colitis in mice

(2008) Reiko Ito et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Regulatory T Cells and Immune Tolerance

(2008) Shimon Sakaguchi et al.   CELL

RORγ-Expressing Th17 Cells Induce Murine Chronic Intestinal Inflammation via Redundant Effects of IL-17A and IL-17F

(2008) Moritz Leppkes et al.   GASTROENTEROLOGY

Th17 Cell Differentiation: The Long and Winding Road

(2008) Mandy J. McGeachy et al.   IMMUNITY

Th17 cells in human disease

(2008) Laura A. Tesmer et al.   IMMUNOLOGICAL REVIEWS

Distinct Cytokine Patterns Identified from Multiplex Profiles of Murine DSS and TNBS-Induced Colitis

(2008) Philip Alex et al.   INFLAMMATORY BOWEL DISEASES

ATP drives lamina propria TH17 cell differentiation

(2008) Koji Atarashi et al.   NATURE