Hepatitis C Virus Proteins Activate NRF2/ARE Pathway by Distinct ROS-Dependent and Independent Mechanisms in HUH7 Cells

Hepatitis C Virus Impairs the Induction of Cytoprotective Nrf2 Target Genes by Delocalization of Small Maf Proteins

(2011) Monica Carvajal-Yepes et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Prevalence and Challenges of Liver Diseases in Patients With Chronic Hepatitis C Virus Infection

(2010) Ira M. Jacobson et al.   Clinical Gastroenterology and Hepatology

Hepatocyte NAD(P)H oxidases as an endogenous source of reactive oxygen species during hepatitis C virus infection

(2010) Nabora Soledad Reyes de Mochel et al.   HEPATOLOGY

Gene Expression Profiling Indicates the Roles of Host Oxidative Stress, Apoptosis, Lipid Metabolism, and Intracellular Transport Genes in the Replication of Hepatitis C Virus

(2010) S. Blackham et al.   JOURNAL OF VIROLOGY

Temporal Proteome and Lipidome Profiles Reveal Hepatitis C Virus-Associated Reprogramming of Hepatocellular Metabolism and Bioenergetics

(2010) Deborah L. Diamond et al.   PLoS Pathogens

Mechanisms and Implications of Reactive Oxygen Species Generation During the Unfolded Protein Response: Roles of Endoplasmic Reticulum Oxidoreductases, Mitochondrial Electron Transport, and NADPH Oxidase

(2009) Célio X.C. Santos et al.   ANTIOXIDANTS & REDOX SIGNALING

Nrf2:INrf2 (Keap1) signaling in oxidative stress

(2009) James W. Kaspar et al.   FREE RADICAL BIOLOGY AND MEDICINE

Antioxidant-induced modification of INrf2 cysteine 151 and PKC-δ-mediated phosphorylation of Nrf2 serine 40 are both required for stabilization and nuclear translocation of Nrf2 and increased drug resistance

(2009) Suryakant K. Niture et al.   JOURNAL OF CELL SCIENCE

Activation of transcription factor Nrf2 by hepatitis C virus induces the cell-survival pathway

(2009) D. Burdette et al.   JOURNAL OF GENERAL VIROLOGY

Hepatitis C virus NS5A and core proteins induce oxidative stress-mediated calcium signalling alterations in hepatocytes

(2009) Natalia Dionisio et al.   JOURNAL OF HEPATOLOGY

Hepatitis C Virus (HCV) Proteins Induce NADPH Oxidase 4 Expression in a Transforming Growth Factor  -Dependent Manner: a New Contributor to HCV-Induced Oxidative Stress

(2009) H. E. Boudreau et al.   JOURNAL OF VIROLOGY

Hepatitis C Virus Infection: Molecular Pathways to Steatosis, Insulin Resistance and Oxidative Stress

(2009) Sophie Clément et al.   Viruses-Basel

Phosphorylation of Nrf2 in the transcription activation domain by casein kinase 2 (CK2) is critical for the nuclear translocation and transcription activation function of Nrf2 in IMR-32 neuroblastoma cells

(2008) Patrick L. Apopa et al.   JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY

Hepatitis C Virus–Induced Reactive Oxygen Species Raise Hepatic Iron Level in Mice by Reducing Hepcidin Transcription

(2007) Sohji Nishina et al.   GASTROENTEROLOGY

Evidence of oxidative stress as a cofactor in the development of insulin resistance in patients with chronic hepatitis C

(2007) Hironori Mitsuyoshi et al.   HEPATOLOGY RESEARCH

Interplay between oxidative stress and hepatic steatosis in the progression of chronic hepatitis C

(2007) Matteo Vidali et al.   JOURNAL OF HEPATOLOGY